HIGHCAT-Identification of patients at HIGH risk of developing urological cancer and Cancer-Associated Thrombosis based on innovative clinical markers and liquid biopsy.

Dades bàsiques

Protocol:
PI20/00075
EURDRACT:
NCT:
Centre:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Any inici:
2021
Any de finalització:
2024
PI BIOMÉDICA NACIONAL Finan. Competitiva Pública 165.770,00 €

Documents

  • No hi ha documents

Participants

Grups d'Investigació

Finançadors - Promotors

INSTITUTO DE SALUD CARLOS III
PILAR MEDINA BADENES

Resultats de l'Assaig Clínic


"In Vitro" Evaluation of Energy-Based Sealing of Graft Side Branches in Bypass Surgery.

Miralles, Manuel; (...); Clara, Albert

Article. 10.1007/s00268-023-07107-0. 2023


A post hoc comparative real-world analysis of HEAD-US score for joint health assessment of patients with severe haemophilia A and B in Spain

Alvarez-Roman, Maria Teresa; (...); Kim, Hae Kyung

Article. 10.1111/hae.14924. 2024


A Series of 14 Polish Patients with Thrombotic Events and PC Deficiency-Novel c.401-1G>A PROC Gene Splice Site Mutation in a Patient with Aneurysms.

Weronska A; (...); Wypasek E

Article. 10.3390/genes13050733. 2022

  • Open Access.

Acute scrotum in children: Management and costs at the emergency room

Gomez, AB; (...); Durba, AS

Meeting Abstract. 2021


An efficiency decision-tree for treating urolithiasis up to 3 cm based on a cost-effective analysis

Gomez, AB; (...); Alba, AB

Meeting Abstract. 2021


Applicability of the Thrombin Generation Test to Evaluate the Hemostatic Status of Hemophilia A Patients in Daily Clinical Practice

Bernardo, Angel; (...); Medina, Pilar

Article. 10.3390/jcm11123345. 2022

  • Open Access.

Association of Vitamin K and Non-Vitamin K Oral Anticoagulant Use and Cancer Incidence in Atrial Fibrillation Patients

Iftimi AA; (...); Sanfélix-Gimeno G

Article. 10.1002/cpt.2362. 2021

  • Open Access.

Benefits of physical activity self-monitoring in patients with haemophilia: a prospective study with one-year follow-up.

Pérez-Alenda S; (...); Núñez-Cortés R

Article. 10.1111/hae.14988. 2024

  • Open Access.

Biomarkers of venous thromboembolism recurrence after discontinuation of anticoagulation for cancer-associated thrombosis (HISPALIS study)

Candelera, RO; (...); Badenes, PM

Meeting Abstract. 2021


Biomarkers of Venous Thromboembolism Recurrence after Discontinuation of Low Molecular Weight Heparin Treatment for Cancer-Associated Thrombosis (HISPALIS-Study).

Otero, Remedios; (...); Medina, Pilar

Article. 10.3390/cancers14112771. 2022

  • Open Access.

Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro.

Herranz R; (...); Medina P

Article. 10.3389/fimmu.2023.1171065. 2023

  • Open Access.

Calprotectin as a new inflammatory marker of abdominal aortic aneurysm: A pilot study.

Plana E; (...); Miralles M

Article. 10.1177/1358863X241231494. 2024


Cerebral calcium embolism.

Asensi Canto, Pedro; (...); Bonanad Boix, Santiago

Article. 10.1002/ccr3.4962. 2022

  • Open Access.

Circulating Cell-Free DNA in Liquid Biopsies as Potential Biomarker for Bladder Cancer: A Systematic Review

Herranz, R; (...); Medina, P

Review. 10.3390/cancers13061448. 2021

  • Open Access.

Clinical benefits of a Bayesian model for plasma-derived factor VIII/VWF after one year of pharmacokinetic-guided prophylaxis in severe/moderate hemophilia A patients

Megias-Vericat, JE; (...); Poveda, JL

Article. 10.1016/j.thromres.2021.07.009. 2021


Comparative analysis of Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) scores in persons with nonsevere hemophilia A and B reveals a high degree of joint damage in both disease types

Jimenez-Yuste, Victor; (...); Kim, Hae Kyung

Letter. 10.1016/j.rpth.2023.102207. 2023

  • Open Access.

Comparison of Three Workstations For Abdominal Aortic Aneurysm Sizing: Impact in Decision Making and Graft Selection

Ribe, Lucas; (...); Miralles, Manuel

Article. 10.1177/15266028221120767. 2024


Comprehensive Screening of Genetic Variants in the Coding Region of F8 in Severe Hemophilia A Reveals a Relationship with Disease Severity in a Colombian Cohort.

Sarmiento Doncel, Samuel; (...); Lopez Guerrero, Jose A

Article. 10.3390/life14081041. 2024

  • Open Access.

Consensus Statement on Hemostatic Management, Anticoagulation, and Antiplatelet Therapy in Liver Transplantation.

Montalvá E; (...); Colmenero J

Article. 10.1097/TP.0000000000004014. 2022

  • Open Access.

CONTRIBUTION OF NETOSIS IN ADVANCED STAGES OF HIGH-GRADE SEROUS OVARIAN CANCER: DIAGNOSTIC IMPLICATIONS

Alexandre, J. Mari; (...); Gilabert-Estelles, J.

Meeting Abstract. 10.1136/ijgc-2021-ESGO.604. 2021

  • Open Access.

Costs of the management of hemophilia A with inhibitors in Spain

Bonanad, S; (...); Gonzalez-Dominguez, A

Article. 10.33393/grhta.2021.2234. 2021

  • Open Access.

Delving into the clinical impact of NETs in pediatric cancer.

Benavent N; (...); Medina P

Article. 10.1038/s41390-024-03437-4. 2024


Development and testing of a mobile app for systematic collection of patient-reported outcomes (PROs) in patients with hemophilia.

Megias-Vericat, J E; (...); Poveda Andres, J L

Letter. 10.1016/j.thromres.2024.109122. 2024


DIAGNOSIS AND MANAGEMENT OF HEMARTHROSIS AND HAEMOPHILIC ARTHROPATHY USING UNIFIED CLINICAL AND ULTRASOUND CRITERIA: PRELIMINARY RESULTS

Chimeno-Hernandez, A; (...); Querol, F

Meeting Abstract. 2021


DIAGNOSIS OF JOINT BLEEDS: PREDICTIVE MODELING BASED ON PATIENT-REPORTED SYMPTOMS

Goldmann, G.; (...); Tiede, A.

Meeting Abstract. 2023


Differences in the expression of microRNAs 16-5p and 451a after acute exercise in patients with thrombosis versus healthy subjects

Lopez, Veronica Sanchez; (...); Candelera, Remedios Otero

Meeting Abstract. 10.1183/13993003.congress-2024.PA535. 2024

  • Open Access.

Differential expression of plasma microRNAs in chronic thromboembolic pulmonary hypertension and pulmonary embolism related to occult cancer

Oto, Julia; (...); Otero, Remedios

Meeting Abstract. 10.1183/13993003.congress-2021.PA593. 2021


Dysregulated neutrophil extracellular traps and haemostatic biomarkers as diagnostic tools and therapeutic targets in periprosthetic joint infection.

Oto, Julia; (...); Medina, Pilar

Article. 10.1302/0301-620X.106B9.BJJ-2024-0187.R1. 2024


Effect of different schemes of androgen deprivation therapy on bone mass density in prostate cancer patients.

Arevalo Ruales, Karla; (...); Roman Ivorra, Jose Andres

Article. 10.1016/j.medcli.2022.03.026. 2023


Effectiveness of progressive moderate-vigorous intensity elastic resistance training on quality of life and perceived functional abilities in people with haemophilia: secondary analysis of a randomized controlled trial.

Cruz-Montecinos C; (...); Calatayud J

Article. 10.1111/ejh.13900. 2022

  • Open Access.

Effects of a non-pharmacological approach for chronic pain management in patients with haemophilia: efficacy of cognitive-behavioural therapy associated with physiotherapy.

García-Dasí M; (...); Bonanad S

Article. 10.1111/hae.14284. 2021


EFFECTS OF MULTIMODAL EXERCISES PROGRAM ON BALANCE, FUNCTIONALITY, RISK OF FALLS AND STRENGTH IN PEOPLE WITH HAEMOPHILIA

Chimeno-Hernandez, A.; (...); Querol, F.

Article. 2022


Efficacy and Hemodynamic Impact of Net-Type Embolic Protection Devices for Endovascular Interventions: Evaluation in an In Vitro Model

Sanchez-Nevarez, Manuel Ignacio; (...); Miralles, Manuel

Meeting Abstract. 2023


EFFICACY AND SAFETY OF EPTACOG BETA (RECOMBINANT HUMAN FVIIA) ACCORDING TO AGE IN PERSONS WITH HAEMOPHILIA A/B WITH INHIBITORS UNDERGOING SURGICAL PROCEDURES

Miesbach, W.; (...); Mahlangu, J.

Meeting Abstract. 2023


Emicizumab-induced photosensitivity.

Asensi Canto, Pedro; (...); Haya Guaita, Saturnino

Article. 10.1055/s-0042-1749092. 2022


EPTACOG BETA EFFICACY AT 24 HOURS POSTINFUSION FOR MILD OR MODERATE BLEEDS IN INDIVIDUALS WITH HEMOPHILIA A OR B AND INHIBITORS

Boggio, Lisa; (...); Escobar, Miguel

Meeting Abstract. 2023


Extrathoracic Aneurysms in Marfan Syndrome: A Systematic Review of the Literature.

Requejo-Garcia, Lucia; (...); Miralles-Hernandez, Manuel

Article. 10.1016/j.avsg.2022.08.005. 2022


Geriatric assessment in hematology scale predicts treatment tolerability in older patients diagnosed with hematological malignancies: The RETROGAH study.

de la Rubia J; (...); Bonanad, Santiago

Article. 10.1016/j.jgo.2022.10.016. 2022

  • Open Access.

Haemophilic arthropathy: basic protocols for clinical examination and imaging.

Querol, F.; (...); Perez-Alenda, S.

Article. 10.1097/MBC.0000000000001215. 2023


Haemotrack: Musculoskeletal management in haemophilia with physiotherapist-driven digital solutions

Perez-Alenda, Sofia; (...); Aguilar-Rodriguez, Marta

Meeting Abstract. 2024


Identification of miR-20a-5p as Robust Normalizer for Urine microRNA Studies in Renal Cell Carcinoma and a Profile of Dysregulated microRNAs

Oto J; (...); Medina P

Article. 10.3390/ijms22157913. 2021

  • Open Access.

IMPACT OF INITIATION OF PROPHYLAXIS, SYNOVITIS AND FUNCTIONALITY ON JOINT HEALTH IN PATIENTS WITH HEMOPHILIA

Chimeno, A.; (...); Bonanad Boix, S.

Meeting Abstract. 2023


Increased levels of NETosis biomarkers in high-grade serous ovarian cancer patients' biofluids: Potential role in disease diagnosis and management.

Tomás-Pérez S; (...); Gilabert-Estellés J

Article. 10.3389/fimmu.2023.1111344. 2023

  • Open Access.

Intra-plaque calcium and its relation with the progression of carotid atheromatous disease.

Miralles, Manuel; (...); Plana, Emma

Article. 10.23736/S0392-9590.22.04872-6. 2022


LC-MS metabolomics of urine reveals distinct profiles for non-muscle-invasive and muscle-invasive bladder cancer

Oto, Julia; (...); Medina, Pilar

Article. 10.1007/s00345-022-04136-7. 2022


Management of flexible cavovarus foot in patients with Charcot-Marie-Tooth disease: midterm results.

Megías-Vericat JE; (...); Poveda-Andrés JL

Article. 2021

  • Open Access.

Management of Urgent Bleeding in Patients with Hemophilia A: Focus on the Use of Emicizumab.

Jiménez-Yuste V; (...); Rodríguez-López M

Article. 10.1055/s-0044-1785525. 2024

  • Open Access.

Matching-Adjusted Indirect Comparison of Efficacy and Consumption of rVIII-SingleChain Versus Two Recombinant FVIII Products Used for Prophylactic Treatment of Adults/Adolescents with Severe Haemophilia A

Bonanad, S; (...); Santos, S

Article. 10.1007/s12325-021-01853-0. 2021

  • Open Access.

Mental, emotional and social dimensions of quality of life and their relationship with physical and functional status in adults with haemophilia.

Rodríguez MA; (...); Chimeno-Hernández A

Article. 10.1016/j.thromres.2024.109181. 2024

  • Open Access.

Metabolomic study for the identification of symptomatic carotid plaque biomarkers

Botello-Marabotto, Marina; (...); Miralles, Manuel

Article. 10.1016/j.talanta.2024.127211. 2025

  • Open Access.

MicroRNAs as predictors of chronic thromboembolic pulmonary hypertension

Otero Candelera, Remedios; (...); Sanchez Lopez, Veronica

Meeting Abstract. 10.1183/13993003.congress-2023.OA4831. 2023


Moderate haemophilia A: Recommendations from a Spanish panel of experts.

Álvarez Román MT; (...); López-Jaime FJ

Article. 10.1111/hae.15110. 2024

  • Open Access.

Monitoring coagulation factors during surgery. A systematic review

Eduardo Megias-Vericat, Juan; (...); Luis Poveda-Andres, Jose

Review. 10.7399/fh.11766. 2021


MONITORING OF THE JOINT HEALTH OF PATIENTS WITH HEMOPHILIA IN SPAIN. INITIAL ANALYSIS OF THE JOINT US PROJECT

Alvarez-Roman, MT; (...); Querol, F

Meeting Abstract. 2021


Multimodal exercises program to improve balance in patients with haemophilia: preliminary results

Chimeno-Hernandez, A; (...); Quero, F

Meeting Abstract. 2021


National Survey on the Use of Mobile Applications in Patients with Hemophilia and Other Coagulopathies

Eduardo Megias, Juan; (...); Poveda Andres, Jose Luis

Meeting Abstract. 10.1182/blood-2022-169938. 2022

  • Open Access.

Near-Infrared Autofluorescence in Atherosclerosis Associates with Ceroid and Is Generated by Oxidized Lipid-Induced Oxidative Stress

Plana Andani, Emma

Article. 10.20960/angiologia.00437. 2022

  • Open Access.

Neutrophil extracellular traps (NETs) in patients with STEMI. Association with percutaneous coronary intervention and antithrombotic treatments.

Ferre-Vallverdu, Mari; (...); Moscardo, Antonio

Article. 10.1016/j.thromres.2022.03.002. 2022


Neutrophil Extracellular Traps and Cancer: Trapping Our Attention with Their Involvement in Ovarian Cancer.

Castano, Maria; (...); Gilabert-Estelles, Juan

Article. 10.3390/ijms24065995. 2023

  • Open Access.

New Roles for Old Friends: Involvement of the Innate Immune System in Tumor Progression.

Castano, Maria; (...); Gilabert-Estelles, Juan

Editorial Material. 10.3390/ijms24087604. 2023

  • Open Access.

Nuclear-medicine probes: Where we are and where we are going

Gonzalez-Montoro A; (...); Javier Gonzalez, Antonio

Article. 10.1002/mp.15690. 2022

  • Open Access.

Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Pegcetacoplan: Real Life Experience

Vallejo, Carlos; (...); Vara, Miriam

Meeting Abstract. 10.1182/blood-2023-185570. 2023


Prostate cancer chemotherapy by intratumoral administration of Docetaxel-Mesoporous silica nanomedicines.

Rivero-Buceta, Eva; (...); Botella, Pablo

Article. 10.1016/j.ijpharm.2024.124623. 2024

  • Open Access.

Real-world analysis of the PK-guided switch from standard half-life factor VIII to efmoroctocog alfa.

Megias-Vericata, J. E.; (...); Poveda Andres, J L

Letter. 10.1016/j.thromres.2023.11.023. 2023


Role of Syndecans in Ovarian Cancer: New Diagnostic and Prognostic Biomarkers and Potential Therapeutic Targets.

Oto, Julia; (...); Gotte, Martin

Article. 10.3390/cancers15123125. 2023

  • Open Access.

Sildenafil Citrate Enhances Renal Organogenesis Following Metanephroi Allotransplantation into Non-Immunosuppressed Hosts.

Garcia-Dominguez, Ximo; (...); Marco-Jimenez, Francisco

Article. 10.3390/jcm11113068. 2022

  • Open Access.

Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients.

Pinana, JL; (...); Bosch F

Article. 10.1080/10428194.2021.1992619. 2021

  • Open Access.

Suitability and readiness assessment of organizational resources for the implementation of gene therapy in hemophilia in Spain and Portugal: A survey-based study.

Villas JMC; (...); Álvarez-Román MT

Letter. 10.1016/j.thromres.2024.109180. 2024


Technological innovations in shock wave lithotripsy

Seoane, L. Mosquera; (...); Fentes, D. A. Perez

Review. 10.1016/j.acuro.2023.09.003. 2024

  • Open Access.

The factor VIII treatment history of non-severe hemophilia A: COMMENT. Joint damage in adult patients with mild or moderate hemophilia A evaluated with the HEAD-US system

Roman, MTA; (...); Mosteirin, NF

Letter. 10.1111/jth.15475. 2021

  • Open Access.

The Limitations and Unmet Needs of the Five Cornerstones to Guarantee Lifelong Optimization of Prophylaxis in Hemophilia Patients.

Nunez, Ramiro; (...); Jimenez-Yuste, Victor

Article. 10.1055/s-0042-1757745. 2022

  • Open Access.

The safety of activated eptacog beta in the management of bleeding episodes and perioperative haemostasis in adult and paediatric haemophilia patients with inhibitors.

Escobar, M; (...); Kessler, C

Article. 10.1111/hae.14419. 2021

  • Open Access.

The sentinel node with technetium-99m for prostate cancer. A safe and, mature new gold standard?

Perez-Ardavin J; (...); Vera-Donoso CD

Article. 10.23736/S1824-4785.22.03416-1. 2022


Thromboembolic hazard in hereditary hemorrhagic telangiectasia.

Asensi Canto, Pedro; (...); Bonanad Boix, Santiago

Article. 10.1002/jha2.471. 2022


Thrombospondins in human aortic aneurysms.

Plana, Emma; (...); Miralles, Manuel

Article. 10.1002/iub.2610. 2022


Thrombotic risk and features of patients with inferior vena cava agenesis: a multicentre, retrospective, observational study.

Bravo-Perez, Carlos; (...); Corral, Javier

Article. 10.1016/S2352-3026(24)00138-8. 2024


Type 2N VWD: Conclusions from the Spanish PCM-EVW-ES project

Perez-Rodriguez, Almudena; (...); Lopez-Fernandez, Maria Fernanda

Article. 10.1111/hae.14405. 2021


Ultrasound evaluation of joint damage and disease activity in adult patients with severe haemophilia A using the HEAD-US system.

Jiménez-Yuste V; (...); Kim HK

Article. 10.1111/hae.14280. 2021


Validation of urine p-cresol glucuronide as renal cell carcinoma non-invasive biomarker

Oto, Julia; (...); Medina, Pilar

Article. 10.1016/j.jprot.2024.105357. 2025


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