ESTUDIO MULTICENTRICO, ALEATORIZADO Y FASE II PARA VALORAR LA SEGURIDAD Y POSIBILIDAD DE RESECCION EN PACIENTES CON METASTASIS, HEPATICAS INICIALMENTE NO RESECABLES SECUNDARIAS A CANCER COLORRECTAL CON TRATAMIENTO DE PRIMERA LINEA CON MFOLFOX-6 MAS BEVACI ZUMAB O FOLFOXIRI MAS BEVACIZUMAB

Datos básicos

Protocolo:
MO18725
EUDRACT:
2007-007863-26
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2009
Año de finalización:
2014
ENSAYO CLÍNICO INTERNACIONAL

Objetivos del proyecto

Observaciones: Estado Comité: FINALIZADO

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

F. HOFFMANN-LA ROCHE LTD

Resultados del Ensayo Clínico


A Phase I, Dose-Finding Study of Sorafenib in Combination with Gemcitabine and Radiation Therapy in Patients with Unresectable Pancreatic Adenocarcinoma: A Grupo Espanol Multidisciplinario en Cancer Digestivo (GEMCAD) Study

Aparicio, J; (...); Maurel, J

Article. 10.1371/journal.pone.0082209. 2014

  • Open Access.

A surgical model for isolating the pig liver in vivo for gene therapy.

Carreño O; (...); Lopez-Andujar R

Article. 10.1159/000351339. 2013


Análisis de minimización de costes de darbepoetina alfa frente a epoetina alfa en pacientes con insuficiencia renal crónica sometidos a hemodiálisis.

Cuesta Grueso C; (...); Romá Sánchez E

Abstract of Published Item. 10.1016/j.farma.2009.12.001. 2010

  • Open Access.

Anaphylaxis Due to Pentoxifylline

Carballada F; (...); Boquete M

Editorial Material. 2014


Anemia is Not Predictive of Sustained Virological Response in Liver Transplant Recipients with Hepatitis C Virus Who are Treated with Pegylated Interferon and Ribavirin

Giusto, Michela; (...); Berenguer, Marina

Article. 10.1002/lt.22387. 2011


Aplicación de la farmacoeconomía en la gestión clínica.

Amat Díaz M, Poveda Andrés JL, Carrera-Hueso FJ

Article. 10.1016/S1130-6343(11)70018-6. 2011

  • Open Access.

Assessment of the effectiveness and safety of natalizumab for treating relapsing-remitting multiple sclerosis.

Fernández-Megía MJ; (...); Poveda-Andrés JL

Article. 10.1016/j.farma.2010.02.003. 2011

  • Open Access.

Baseline Pegylated Interferon (PIFN) and Calcineurin Inhibitor (CNI): No Impact on Sustained Viral Response (SVR) Post-Liver Transplantation

Aguilera, Victoria; (...); Berenguer, Marina

Article. 2011


Effect of Calcineurin Inhibitors in the Outcome of Liver Transplantation in Hepatitis C Virus-Positive Recipients

Berenguer, Marina; (...); Prieto, Martin

Article. 10.1097/TP.0b013e3181fa93fa. 2010


EFFECT OF CYP3A5 GENOTYPE ON TACROLIMUS DOSE REQUIREMENT, NEPHROTOXICITY AND ACUTE REJECTION IN KIDNEY TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES

Rojas, L.; (...); Alino, S. F.

Article. 2013


EFFECTS OF POLYMORPHIMS OF CYP3A5 AND ABCB1 GENES ON CHRONIC NEPHROPATHY: COHORT STUDY

Rojas, L.; (...); Alino, S. F.

Article. 2013


Efficacy of gene transfer to "in vivo'' whole isolated pig liver

Sendra, L.; (...); Alino, S. F.

Article. 2012


Estimation of the elastic parameters of human liver biomechanical models by means of medical images and evolutionary computation.

Martínez-Martínez F; (...); López-Andújar R

Article. 10.1016/j.cmpb.2013.05.005. 2013


Estudio de utilizacion de boceprevir y telaprevir para el tratamiento de la hepatitis C cronica.

Marrero-Álvarez P; (...); Poveda-Andrés JL

Abstract of Published Item. 10.7399/FH.2014.38.1.1128. 2014

  • Open Access.

Evaluación de un programa de conciliación e información al paciente trasplantado cardíaco.

Hernández Martín J; (...); Poveda Andrés JL

Abstract of Published Item. 10.1016/j.farma.2009.09.002. 2010

  • Open Access.

Has Laparoscopic Kasai Portoenterostomy Got Any Advantage in Pediatric Liver Transplant Patients?

Vila Carbo, Juan Jose; (...); Dejuan, Manolo

Article. 2011


Hepatolitiasis simulando un colangiocarcinoma hiliar.

Vergara Suárez F; (...); Pérez Rojas J

Letter. 10.1016/j.ciresp.2013.03.003. 2013


Importance of Technical Aspects in the Beginnings of a Pancreas Transplantation Program

Moya Herraiz, A.; (...); Mir Pallardo, J.

Article. 10.1016/j.transproceed.2009.12.001. 2010


Incidence of hand-foot syndrome with capecitabine in combination with chemotherapy as first-line treatment in patients with advanced and/or metastatic gastric cancer suitable for treatment with a fluoropyrimidine-based regimen.

Gómez-Martin C; (...); López RL

Article. 10.1007/s12094-012-0858-3. 2012


Increased hospital stay and allograft dysfunction in renal transplant recipients with Cyp2c19 AA variant in SNP rs4244285.

Bosó V; (...); Aliño SF

Article. 10.1124/dmd.112.047977. 2013


Indications and results of liver retransplantation: experience with 1181 patients in the hospital universitario La Fe

Torres-Queuedo, Rodrigo; (...); Mir, Jose

Article. 10.1016/j.ciresp.2009.10.012. 2010


Inefficient RNA translation limits the efficacy of hydrodynamic gene transfer to pig liver "in vivo"

Sendra, L.; (...); Alino, S. F.

Article. 2013


Long-term outcome of "long-term liver transplant survivors"

Berenguer, Marina; (...); Prieto, Martin

Article. 2012


LONG-TERM OUTCOME OF LIVER TRANSPLANTATION FOR HEPATITIS B WITH ANTI-HBC POSITIVE GRAFTS

Garcia-Eliz, M.; (...); Prieto, M.

Article. 10.1016/S0168-8278(12)60208-6. 2012


Long-Term Outcome of Liver Transplantation for Hepatitis B with Anti-HBc Positive Grafts.

Garcia-Eliz, Maria; (...); Prieto, Martin

Article. 2012


Long-term outcome of 'long-term liver transplant survivors'.

Rubín A; (...); Berenguer M

Article. 10.1111/tri.12118. 2013


Long-term results with oral fluoropyrimidines and oxaliplatin-based preoperative chemoradiotherapy in patients with resectable rectal cancer. A single-institution experience

Diaz Beveridge, Robert; (...); Ramos, David

Article. 10.1007/s12094-012-0826-y. 2012


Management of advanced pancreatic cancer with gemcitabine plus erlotinib: efficacy and safety results in clinical practice.

Diaz Beveridge R; (...); Montalar J

Article. 10.6092/1590-8577/1570. 2014


Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.

Rojas LE; (...); Aliño SF

Article. 10.1097/FPC.0b013e3283642fb3. 2013


Metastasis of the gallbladder in clear cell renal carcinoma

Bosca Robledo, Andrea; (...); De Juan Burgueno, Manuel

Article. 10.3892/ol.2012.616. 2012


Monitorización de errores de medicación en dispensación individualizada mediante el método del carro centinela.

Pérez-Cebrián M; (...); Poveda-Andrés JL

Abstract of Published Item. 10.1016/j.farma.2010.06.004. 2011

  • Open Access.

Oxaliplatin in combination with infusional 5-fluorouracil as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumors.

Benavides M; (...); Aranda E

Article. 10.1016/j.clcc.2012.01.003. 2012


Paclitaxel and carboplatin treatment for advanced ovarian cancer during pregnancy.

Ruiz Ramos J; (...); Poveda JL

Article. 10.1159/000360691. 2013


Panitumumab and irinotecan every 3 weeks is an active and convenient regimen for second-line treatment of patients with wild-type K-RAS metastatic colorectal cancer.

Carrato A; (...); Aranda E

Article. 10.1007/s12094-012-0993-x. 2013


PATIENTS SURVIVING AT LEAST 10 YEARS POST LIVER TRANSPLANTATION: LONG TERM RESULTS

Berenguer, M.; (...); Prieto, M.

Article. 2011


Pharmacogenetic predictors of severe peripheral neuropathy in colon cancer patients treated with oxaliplatin-based adjuvant chemotherapy: a GEMCAD group study

Custodio, A; (...); Feliu, J

Article. 10.1093/annonc/mdt546. 2014


POST-LIVER TRANSPLANTATION (LT) OUTCOME IN HIV/HCV CO-INFECTED PATIENTS. COMPARISON WITH MONOINFECTED PATIENTS WITH HCV-CIRRHOSIS

Aguilera, V.; (...); Prieto, M.

Article. 10.1016/S0168-8278(11)60519-9. 2011


Renal Transplantation Recipients with AA Genotype in SNP rs4244285 of CYP2C19 Show An Increase in Hospital Stay Duration and Allograft Dysfunction Probably Due to Increased Tacrolimus Levels Caused by Interaction with Omeprazol

Boso, V; (...); Alino, S. F.

Article. 10.1097/00007890-201211271-01757. 2012


Selective ophthalmic intra-arterial melphalan therapy for advanced retinoblastoma: implementation and outcomes of a new chemotherapy protocol.

Valero García S; (...); Poveda Andrés JL

Article. 10.1177/1078155212457964. 2013


SNPs and taxane toxicity in breast cancer patients

Bosó V; (...); Aliño SF

Article. 10.2217/PGS.14.127. 2014


Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature

Lizan, L; (...); Polanco, C

Review. 10.2147/PPA.S67253. 2014

  • Open Access.

T-tube or no T-tube in cadaveric orthotopic liver transplantation: the eternal dilemma: results of a prospective and randomized clinical trial.

López-Andújar R; (...); De Juan Burgueño M

Article. 10.1097/SLA.0b013e318286e0a0. 2013


T-Tube or Not T-Tube in Deceased Donor Liver Transplantation. Preliminary Results of a Prospective Randomized Trial

Lopez-Andujar, Rafael; (...); Mir, Jose

Article. 2011


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