Portal de investigación
ESTUDIO DE INDUCCION DE INMUNOTOLERANCIA EN PACIENTES CON HEMOFILIA A GRAVE CON INHIBIDOR TRAS FRACASO PREVIO EN INDUCCION DE INMUNOTOLERANCIA UTILIZANDO CONCENTRADOS DE FVIII SIN FACTOR VON WILLEBRAND.
Datos básicos
- Código:
- RESIST-EXPERIENCED
- Protocolo:
- RESIST-EXPERIENCED
- EUDRACT:
- 2008-007019-33
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- Año de incio:
- 2010
- Año de finalización:
- 2013
Objetivos del proyecto
Observaciones: Estado Comité: FINALIZADO
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A simplified assay for quantification of circulating activated protein C levels
Medina, P.; (...); Espana, F.
Article. 2013
Assessment of the thrombin generation assay in haemophilia: comparative study between fresh and frozen platelet-rich plasma.
Vila V; (...); España F
Article. 10.1111/hae.12044. 2013
Association of haplotypes (H) 1 and 3 of the endothelial protein c receptor gene (PROCR) with venous thromboembolism
Bonet, Elena; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.027. 2012
Association of haplotypes (H) 1 and 3 of the endothelial protein C receptor gene (PROCR) with venous thromboembolism
Navarro, S.; (...); Medina, P.
Article. 2013
Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method
Cabrera, N.; (...); Aznar, J. A.
Article. 2013
Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method.
Cabrera N; (...); Aznar JA
Article. 10.1111/hae.12203. 2013
Deletion of F8 gene involving the segmental repeat int22h and one of the two extragenic copies in a carrier woman
Casana, P.; (...); Aznar, J. A.
Article. 2011
Efficacy of factor IX Grifols(®) in surgery: experience of an international multicentre retrospective study.
Pérez-Garrido R; (...); Rescia V
Letter. 10.1111/j.1365-2516.2012.02919.x. 2012
Emerging viral infections--a potential threat for blood supply in the 21st century.
de Mendoza C; (...); Soriano V
Article. 2012
Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A.
Eckhardt CL; (...); Fijnvandraat K
Article. 10.1182/blood-2013-02-483263. 2013
Factor VIII products and inhibitor development in severe hemophilia A.
Gouw SC; (...); van den Berg HM
Article. 10.1056/NEJMoa1208024. 2013
First application of MLPA method in severe von Willebrand disease. Confirmation of a new large VWF gene deletion and identification of heterozygous carriers.
Cabrera N; (...); Aznar JA
Letter. 10.1111/j.1365-2141.2010.08400.x. 2011
Haplotypes of the endothelial protein C receptor gene and circulating protein C levels
Martos, L.; (...); Medina, P.
Article. 2013
Haplotypes of the endothelial protein C receptor gene and circulating protein C levels
Martos, Laura; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.026. 2012
Head-to-head comparison of the pharmacokinetic profiles of a high-purity factor IX concentrate (AlphaNine®) and a recombinant factor IX (BeneFIX®) in patients with severe haemophilia B.
Lissitchkov T; (...); Páez A
Article. 10.1111/hae.12148. 2013
Identification of mutations in the protein C gene in a panel of 65 Spanish families with protein C deficiency
Martos, Laura; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.029. 2012
Is on-demand treatment effective in patients with severe haemophilia?
Aznar JA; (...); Moret A
Article. 10.1111/j.1365-2516.2012.02806.x. 2012
Kinetics of the interaction between anti-FVIII antibodies and FVIII from therapeutic concentrates, with and without von Willebrand factor, assessed by surface plasmon resonance.
Grancha S; (...); Aznar JA
Article. 10.1111/j.1365-2516.2012.02858.x. 2012
Large deletion in the Factor VIII gene (F8) involving segmental duplications in int22h shows no haematological phenotype in female carriers, but may be embryonic lethal in males.
Casaña P; (...); MARTINEZ, F.
Letter. 10.1111/j.1365-2141.2012.09092.x. 2012
Liver transplantation in Spanish haemophiliacs.
Aznar JA; (...); Soto I
Letter. 10.1111/j.1365-2516.2011.02658.x. 2012
The Spanish Immune Tolerance Induction Registry: 2009 update
Haya, S.; (...); Aznar, J. A.
Article. 2010