Portal de recerca
ESTUDIO DE FASE 3, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, PARA EVALUAR TADALAFILO EN LA DISTROFIA MUSCULAR DE DUCHENNE.
Dades bàsiques
- Protocol:
- H6D-MC-LVJJ
- EURDRACT:
- 2013-001194-25
- NCT:
- Centre:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Any inici:
- 2013
- Any de finalització:
- 2016
Objectius del projecte
Observaciones: Estado Comité: FINALIZADO
Documents
- No hi ha documents
Participants
Grups d'Investigació
Finançadors - Promotors
Resultats de l'Assaig Clínic
[Farewell open letter to SEFH members].
Editorial Material. 10.7399/fh.2015.39.6.10128. 2015
A mutation in TNPO3 causes LGMD1F and characteristic nuclear pathology
Kubota, A.; (...); Hirano, M.
Article. 10.1016/j.nmd.2013.06.464. 2013
A systematic review and meta-analysis of the impact of WT1 polymorphism rs16754 in the effectiveness of standard chemotherapy in patients with acute myeloid leukemia
Megías-Vericat JE; (...); Aliño SF
Article. 10.1038/tpj.2015.80. 2016
Aflibercept in exudative age related macular degeneration refractory to ranibizumab.
Ruiz Ramos J; (...); Gallego-Pinazo R
Article. 10.1016/j.oftal.2015.07.018. 2015
Analisis de las causas de suspension de tratamiento con triple terapia antiviral en pacientes con hepatitis C.
Ruiz Ramos J; (...); Poveda Andrés JL
Abstract of Published Item. 10.7399/fh.2014.38.3.1171. 2014
Anidulafungin-Induced Alopecia
Ruiz-Ramos J; (...); Poveda-Andrés JL
Article. 10.1177/1060028014524534. 2014
Assessment of Targeted Next-Generation Sequencing as a Tool for the Diagnosis of Charcot-Marie-Tooth Disease and Hereditary Motor Neuropathy
Article. 10.1016/j.jmoldx.2015.10.005. 2016
Assessment of the quality of sample labelling for clinical research.
Pérez-Huertas P; (...); Poveda-Andrés JL
Article. 10.7399/fh.2016.40.2.9753. 2016
Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation
Sánchez-Lázaro I; (...); Aliño SF
Article. 10.2217/pgs.15.39. 2015
Biosimilares: viejas polemicas con nuevos argumentos.
Poveda-Andrés JL, Bosó-Ribelles V
Editorial Material. 10.7399/fh.2015.39.3.8978. 2015
Calidad y Legibilidad de la Hoja de Informacion al Paciente en Estudios con Analisis Farmacogenetico.
Ruiz Ramos J; (...); Poveda Andrés JL
Article. 2015
Clinical and neuroimaging characterization of two C9orf72-positive siblings with amyotrophic lateral sclerosis and schizophrenia
Vázquez-Costa JF; (...); Sevilla T
Article. 10.3109/21678421.2015.1112407. 2016
Clinical evaluation of rituximab treatment for neuromyelitis optica
Fernández-Megía MJ; (...); Poveda-Andrés JL
Article. 10.1016/j.nrl.2014.09.001. 2015
Clinical experiences with cannabinoids in spasticity management in multiple sclerosis
Lorente Fernández L; (...); Casanova-Estruch B
Article. 10.1016/j.nrl.2013.06.014. 2014
Clinical phenotype, muscle MRI and muscle pathology of LGMD1F.
Peterle E; (...); Angelini C
Article. 10.1007/s00415-013-6931-1. 2013
CMT genetic distribution in Spanish TREAT-CMT consortium
Sivera, R.; (...); Sevilla, T.
Meeting Abstract. 2015
Cost-effectiveness of methoxy polyethylene glycolepoetin beta versus conventional epoetin in the treatment of anaemia secondary to chronic kidney disease in clinical practice
Lorente-Fernandez, L; (...); Poveda-Andres, JL
Article. 10.1136/ejhpharm-2013-000426. 2015
Charcot-Marie-Tooth disease Genetic and clinical spectrum in a Spanish clinical series
Sivera, Rafael; (...); Espinos, Carmen
Article. 10.1212/WNL.0b013e3182a9f56a. 2013
Charcot-Marie-Tooth disease: genetic and clinical spectrum in a Spanish clinical series.
Sivera R; (...); Espinós C
Article. 10.1212/WNL.0b013e3182a9f56a. 2013
Dose banding aplicado a la elaboracion de antineoplasicos: una revision narrativa de la literatura.
Pérez Huertas P; (...); Poveda Andrés JL
Article. 10.7399/fh.2015.39.4.8839. 2015
Dried Blood Spot for Screening for Late-Onset Pompe Disease: A Spanish Cohort.
Gutiérrez-Rivas E; (...); Lukacs Z
Article. 2015
Drug Interaction Between Oral Cyclosporine Modified and Iron
Domingo-Chiva, E; (...); Poveda-Andres, JL
Article. 10.1177/1060028013514734. 2014
ECONOMIC IMPACT LINKED TO THE REDUCTION OF EXACERBATIONS WHEN A TREATMENT REGIME WITH INHALED ANTIBIOTICS IS SWITCHED TO AZTREONAM LYSINE IN PATIENTS WITH CYSTIC FIBROSIS AND CHRONIC PULMONARY INFECTION CAUSED BY PSEUDOMONAS AERUGINOSA
Sole A; (...); Casado MA
Meeting Abstract. 10.1016/j.jval.2014.08.1659. 2014
EFFECT OF CYP3A5 GENOTYPE ON TACROLIMUS DOSE REQUIREMENT, NEPHROTOXICITY AND ACUTE REJECTION IN KIDNEY TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES
Rojas, L.; (...); Alino, S. F.
Article. 2013
Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies
Rojas L; (...); Aliño SF
Article. 10.1038/tpj.2014.38. 2015
EFFECTS OF POLYMORPHIMS OF CYP3A5 AND ABCB1 GENES ON CHRONIC NEPHROPATHY: COHORT STUDY
Rojas, L.; (...); Alino, S. F.
Article. 2013
Estudio de utilizacion de boceprevir y telaprevir para el tratamiento de la hepatitis C cronica.
Marrero-Álvarez P; (...); Poveda-Andrés JL
Abstract of Published Item. 10.7399/FH.2014.38.1.1128. 2014
Experience in the management of immunosuppressant treatment with hepatitis C virus protease inhibitors
Ruiz Ramos J; (...); Poveda Andrés JL
Article. 10.1016/j.gastrohep.2014.05.004. 2014
EXPERTS CONSENSUS ON THE FUTURE OF RARE DISEASES CARE AND ORPHAN DRUGS ACCESS IN SPAIN: A DELPHI STUDY
Paz S; (...); Urcelay J
Meeting Abstract. 10.1016/j.jval.2015.09.2016. 2015
Genotype and Allele Frequencies of Drug-Metabolizing Enzymes and Drug Transporter Genes Affecting Immunosuppressants in the Spanish White Population
Bosó V; (...); Aliño SF
Article. 10.1097/FTD.0b013e3182a94e65. 2014
Guidelines for monitoring late-onset Pompe disease
Gutieerrez-Rivas, E; (...); de Munain, AL
Article. 10.33588/rn.6007.2015029. 2015
Hazardous drugs: new challenges, new opportunities.
Valero García S; (...); Poveda Andrés JL
Article. 10.7399/fh.2016.40.2.10462. 2016
Identification of a novel gene involved in Charcot-Marie-Tooth disease
Sivera, R.; (...); Espinos, C.
Meeting Abstract. 2015
Impact of Single Nucleotide Polymorphisms (SNPs) on Immunosuppressive Therapy in Lung Transplantation
Ruiz J; (...); Aliño SF
Article. 10.3390/ijms160920168. 2015
Impact of Transporter Genes Polymorphisms in Standard Induction of Acute Myeloid Leukemia
Eduardo Megias, Juan; (...); Angel Sanz, Miguel
Meeting Abstract. 2015
Incompatibility of undiluted busulfan injection with a needle-free valve
Cueto-Sola, M; (...); Poveda-Andres, JL
Letter. 10.2146/ajhp140111. 2014
Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model
Bargiela A; (...); Artero R
Article. 10.1242/dmm.018127. 2015
Inflammatory amyloid angiopathy
Vazquez-Costa, JF; (...); Vilchez-Padilla, JJ
Letter. 10.1016/j.nrl.2012.06.004. 2014
Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: A systematic review and meta-analysis of observational studies
Megías-Vericat JE; (...); Aliño SF
Review. 10.1038/tpj.2014.80. 2015
Influence of Single Nucleotide Polymorphisms in Anthracycline Metabolism Pathway in Standard Induction of Acute Myeloid Leukemia
Eduardo Megias, Juan; (...); Angel Sanz, Miguel
Meeting Abstract. 2015
Junctophilin-1 is a modifier gene of GDAP1-related Charcot-Marie-Tooth disease
Pla-Martín D; (...); Espinós C
Article. 10.1093/hmg/ddu440. 2015
Long-term follow up of patients with dystrophin deficiency and isolated hyperCKemia
Marti, P; (...); Vilchez, J.
Article. 2015
Long-term follow-up in patients with congenital myasthenic syndrome due to RAPSN mutations
Natera-de Benito D; (...); Nascimento A
Article. 10.1016/j.nmd.2015.10.013. 2016
Long-term follow-up of patients with dystrophin deficiency and isolated hyperCKemia
Marti, P.; (...); Vilchez, J. J.
Meeting Abstract. 2015
Long-term outcome in chronic inflammatory demyelinating polyneuropathy patients treated with intravenous immunoglobulin: a retrospective study.
Querol L; (...); Illa I
Article. 10.1002/mus.23843. 2013
Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.
Rojas LE; (...); Aliño SF
Article. 10.1097/FPC.0b013e3283642fb3. 2013
Muscle imaging in muscle dystrophies produced by mutations in the EMD and LMNA genes
Díaz-Manera J; (...); Illa I
Article. 10.1016/j.nmd.2015.10.001. 2016
Muscle MRI and CT help to differentiate between mutations in emerin and lamin A/C gene in patients with Emery Dreifuss clinical phenotypes
Diaz-Manera, J.; (...); Illa, I.
Meeting Abstract. 10.1016/j.nmd.2014.06.173. 2014
Mutations in the MORC2 gene cause axonal Charcot-Marie-Tooth disease
Article. 10.1093/brain/awv311. 2016
Myocarditis and acute coronary syndrome in childhood
Andres, AS; (...); Moreno, JIC
Letter. 10.1016/j.anpedi.2013.11.027. 2014
N. VICTOR JIMENEZ TORRES (1942-2015) IN MEMORIAM
Climente Martí M, Poveda Andrés JL, Culebras J
Biographical-Item. 10.3305/nh.2015.32.4.9704. 2015
NOVEL MUTATIONS IN THE GAMMA CARBOXYLASE GENE CAUSING VKCFD1
Angeles Dasi, M.; (...); Corral, J.
Meeting Abstract. 2014
Novel Mutations Widen the Phenotypic Spectrum of Slow Skeletal/-Cardiac Myosin (MYH7) Distal Myopathy
Lamont PJ; (...); Laing NG
Article. 10.1002/humu.22553. 2014
Positive impact of ABCB1 polymorphisms in overall survival and complete remission in acute myeloid leukemia: a systematic review and meta-analysis
Megías-Vericat JE; (...); Aliño SF
Letter. 10.1038/tpj.2015.79. 2016
Prognostic features of LGMD presenting as symptomatic or paucisymptomatic hyperCKemia
Marti, P; (...); Vilchez, J.
Article. 2015
Prognostic Impact of Anthracycline Metabolism Gene Polymorphisms in Newly Diagnosed Acute Myeloid Leukemia Adults
Eduardo Megias, Juan; (...); Angel Sanz, Miguel
Article. 2014
Prognostic Impact of Cytarabine Pathway Gene Polymorphisms in Acute Myeloid Leukemia Adults Undergoing Induction Chemotherapy
Eduardo Megias, Juan; (...); Angel Sanz, Miguel
Article. 2014
PROGNOSTIC IMPACT OF TRANSPORTER GENE POLYMORPHISMS IN NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA ADULTS
Megias Vericat, J. E.; (...); Sanz, M. A.
Article. 2015
Pseudoaneurisma ventricular izquierdo durante valvuloplastia aortica neonatal.
Sanchez Andres A, Insa Albert B, Carrasco Moreno JI
Article. 10.1016/j.anpedi.2014.09.010. 2015
Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3
Kornak U; (...); Kurth I
Article. 10.1093/brain/awt357. 2014
Single Nucleotide Polymorphisms, SNPs, Associated With the Efficacy and Security of Immunosuppressive Treatment in Heart Transplantation
Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.
Article. 10.1016/j.healun.2014.01.392. 2014
Small fiber neuropathy associated with copper deficiency
Ibanez, M. J.; (...); Vilchez, J. J.
Meeting Abstract. 2015
SNPs and taxane toxicity in breast cancer patients
Bosó V; (...); Aliño SF
Article. 10.2217/PGS.14.127. 2014
Spanish Consensus on the Prevention and Treatment of Pseudomonas aeruginosa Bronchial Infections in Cystic Fibrosis Patients
Cantón R; (...); Solé A
Article. 10.1016/j.arbres.2014.09.021. 2015
Study on the Linezolid Prescription According to the Approval of Indication in a University Hospital
Pérez-Cebrián M; (...); Llopis-González A
Article. 2015
Targeted screening for the detection of Pompe disease in patients with unclassified limb-girdle muscular dystrophy or asymptomatic hyperCKemia using dried blood: A Spanish cohort
Gutiérrez-Rivas E; (...); Lukacs Z
Article. 10.1016/j.nmd.2015.04.008. 2015
The EGR2 gene is involved in axonal Charcot-Marie-Tooth disease
Article. 10.1111/ene.12782. 2015
The natural history of HSJ1-related hereditary neuropathies: a case series of 9 patients with long-term follow-up
Frasquet Carrera, M.; (...); Sevilla, T.
Meeting Abstract. 2015
Trans-arterial chemoembolization with doxorubicin-eluting particles versus conventional trans-arterial chemoembolization in unresectable hepatocellular carcinoma: A study of effectiveness, safety and costs.
Megías Vericat JE; (...); Poveda Andrés JL
Article. 10.1016/j.rx.2015.01.008. 2015
Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature
Lizan, L; (...); Polanco, C
Review. 10.2147/PPA.S67253. 2014
Vestibular impairment in Charcot-Marie-Tooth disease type 4C
Pérez-Garrigues H; (...); Sevilla T
Letter. 10.1136/jnnp-2013-307421. 2014