CARACTERIZACIÓN GENÉTICA DE LAS DEFICIENCIAS FAMILIARES DE PROTEÍNA C. BASES MOLECULARES Y RELACIÓN FENOTIPO-GENOTIPO.

Dades bàsiques

Protocol:
2019-192-1_CRC_MEDINA-NAVARRO
EURDRACT:
NCT:
Centre:
Any inici:
2019
Any de finalització:
2023
PI BIOMÉDICA NACIONAL Finan. Competitiva Privada 10.000,00 €

Documents

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Participants

Grups d'Investigació

Finançadors - Promotors

FUNDACION ESPAÑOLA DE TROMBOSIS Y HEMOSTASIA

Resultats de l'Assaig Clínic


"In Vitro" Evaluation of Energy-Based Sealing of Graft Side Branches in Bypass Surgery.

Miralles, Manuel; (...); Clara, Albert

Article. 10.1007/s00268-023-07107-0. 2023


A predictive model for prostate cancer incorporating PSA molecular forms and age.

Oto J; (...); Navarro S

Article. 10.1038/s41598-020-58836-4. 2020

  • Open Access.

A Series of 14 Polish Patients with Thrombotic Events and PC Deficiency-Novel c.401-1G>A PROC Gene Splice Site Mutation in a Patient with Aneurysms.

Weronska A; (...); Wypasek E

Article. 10.3390/genes13050733. 2022

  • Open Access.

Activated protein C assays: a review.

Oto J; (...); Medina P

Review. 10.1016/j.cca.2019.11.005. 2020


Applicability of the Thrombin Generation Test to Evaluate the Hemostatic Status of Hemophilia A Patients in Daily Clinical Practice

Bernardo, Angel; (...); Medina, Pilar

Article. 10.3390/jcm11123345. 2022

  • Open Access.

Biomarkers of venous thromboembolism recurrence after discontinuation of anticoagulation for cancer-associated thrombosis (HISPALIS study)

Candelera, RO; (...); Badenes, PM

Meeting Abstract. 2021


Biomarkers of Venous Thromboembolism Recurrence after Discontinuation of Low Molecular Weight Heparin Treatment for Cancer-Associated Thrombosis (HISPALIS-Study).

Otero, Remedios; (...); Medina, Pilar

Article. 10.3390/cancers14112771. 2022

  • Open Access.

Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro.

Herranz R; (...); Medina P

Article. 10.3389/fimmu.2023.1171065. 2023

  • Open Access.

Calprotectin as a new inflammatory marker of abdominal aortic aneurysm: A pilot study.

Plana E; (...); Miralles M

Article. 10.1177/1358863X241231494. 2024


Circulating Cell-Free DNA in Liquid Biopsies as Potential Biomarker for Bladder Cancer: A Systematic Review

Herranz, R; (...); Medina, P

Review. 10.3390/cancers13061448. 2021

  • Open Access.

Comparison of Three Workstations For Abdominal Aortic Aneurysm Sizing: Impact in Decision Making and Graft Selection

Ribe, Lucas; (...); Miralles, Manuel

Article. 10.1177/15266028221120767. 2024


CONTRIBUTION OF NETOSIS IN ADVANCED STAGES OF HIGH-GRADE SEROUS OVARIAN CANCER: DIAGNOSTIC IMPLICATIONS

Alexandre, J. Mari; (...); Gilabert-Estelles, J.

Meeting Abstract. 10.1136/ijgc-2021-ESGO.604. 2021

  • Open Access.

Delving into the clinical impact of NETs in pediatric cancer.

Benavent N; (...); Medina P

Article. 10.1038/s41390-024-03437-4. 2024


Differences in the expression of microRNAs 16-5p and 451a after acute exercise in patients with thrombosis versus healthy subjects

Lopez, Veronica Sanchez; (...); Candelera, Remedios Otero

Meeting Abstract. 10.1183/13993003.congress-2024.PA535. 2024

  • Open Access.

Differential expression of plasma microRNAs in chronic thromboembolic pulmonary hypertension and pulmonary embolism related to occult cancer

Oto, Julia; (...); Otero, Remedios

Meeting Abstract. 10.1183/13993003.congress-2021.PA593. 2021


Dysregulated neutrophil extracellular traps and haemostatic biomarkers as diagnostic tools and therapeutic targets in periprosthetic joint infection.

Oto, Julia; (...); Medina, Pilar

Article. 10.1302/0301-620X.106B9.BJJ-2024-0187.R1. 2024


Efficacy and Hemodynamic Impact of Net-Type Embolic Protection Devices for Endovascular Interventions: Evaluation in an In Vitro Model

Sanchez-Nevarez, Manuel Ignacio; (...); Miralles, Manuel

Meeting Abstract. 2023


Extrathoracic Aneurysms in Marfan Syndrome: A Systematic Review of the Literature.

Requejo-Garcia, Lucia; (...); Miralles-Hernandez, Manuel

Article. 10.1016/j.avsg.2022.08.005. 2022


Hemodynamic impact analysis of mesh-type embolic protection devices in an in vitro model

Nevarez, MIS, Andani, EP, Hernandez, MM

Article. 10.20960/angiologia.00101. 2020

  • Open Access.

IDENTIFICATION OF 58 MUTATIONS (26 NEW) IN 94 OF 109 BEING TESTED WITH PROTEIN DEFICIENCY C. SETH WORKING GROUP

Fernandez-Pardo, A.; (...); Navarro, S.

Meeting Abstract. 2019

  • Open Access.

IDENTIFICATION OF A PROFILE OF CLASSES OF CIRCULATING LIPIDS ASSOCIATED WITH THE VENOUS THROMBOEMBOLISM

Fernandez-Pardo, A.; (...); Navarro, S.

Meeting Abstract. 2019

  • Open Access.

Identification of miR-20a-5p as Robust Normalizer for Urine microRNA Studies in Renal Cell Carcinoma and a Profile of Dysregulated microRNAs

Oto J; (...); Medina P

Article. 10.3390/ijms22157913. 2021

  • Open Access.

Identification of miR-29c-3p as a Robust Normalizer for Urine microRNA Studies in Bladder Cancer.

Oto J; (...); Medina P

Article. 10.3390/biomedicines8110447. 2020

  • Open Access.

Identification of Novel microRNA Profiles Dysregulated in Plasma and Tissue of Abdominal Aortic Aneurysm Patients

Plana E; (...); Miralles M

Article. 10.3390/ijms21134600. 2020

  • Open Access.

Increase of Neutrophil Activation Markers in Venous Thrombosis-Contribution of Circulating Activated Protein C

Martos L; (...); Medina P

Article. 10.3390/ijms21165651. 2020

  • Open Access.

INCREASED LEVELS OF FREE CIRCULATING DNA AND DNASE 1 ACTIVITY IN PLASMA IS ASSOCIATED WITH AN INCREASED RISK OF VENOUS THROMBOEMBOLISM

Oto, J.; (...); Medina, P.

Meeting Abstract. 2019

  • Open Access.

Increased levels of NETosis biomarkers in high-grade serous ovarian cancer patients' biofluids: Potential role in disease diagnosis and management.

Tomás-Pérez S; (...); Gilabert-Estellés J

Article. 10.3389/fimmu.2023.1111344. 2023

  • Open Access.

Intra-plaque calcium and its relation with the progression of carotid atheromatous disease.

Miralles, Manuel; (...); Plana, Emma

Article. 10.23736/S0392-9590.22.04872-6. 2022


LC-MS metabolomics of urine reveals distinct profiles for non-muscle-invasive and muscle-invasive bladder cancer

Oto, Julia; (...); Medina, Pilar

Article. 10.1007/s00345-022-04136-7. 2022


Metabolomic study for the identification of symptomatic carotid plaque biomarkers

Botello-Marabotto, Marina; (...); Miralles, Manuel

Article. 10.1016/j.talanta.2024.127211. 2025

  • Open Access.

microRNAs and Markers of Neutrophil Activation as Predictors of Early Incidental Post-Surgical Pulmonary Embolism in Patients with Intracranial Tumors

Oto, J; (...); Medina, P

Article. 10.3390/cancers12061536. 2020

  • Open Access.

MicroRNAs and Neutrophil Activation Markers Predict Venous Thrombosis in Pancreatic Ductal Adenocarcinoma and Distal Extrahepatic Cholangiocarcinoma.

Oto J; (...); Medina P

Article. 10.3390/ijms21030840. 2020

  • Open Access.

MicroRNAs as predictors of chronic thromboembolic pulmonary hypertension

Otero Candelera, Remedios; (...); Sanchez Lopez, Veronica

Meeting Abstract. 10.1183/13993003.congress-2023.OA4831. 2023


Near-Infrared Autofluorescence in Atherosclerosis Associates with Ceroid and Is Generated by Oxidized Lipid-Induced Oxidative Stress

Plana Andani, Emma

Article. 10.20960/angiologia.00437. 2022

  • Open Access.

Neutrophil Extracellular Traps and Cancer: Trapping Our Attention with Their Involvement in Ovarian Cancer.

Castano, Maria; (...); Gilabert-Estelles, Juan

Article. 10.3390/ijms24065995. 2023

  • Open Access.

New Roles for Old Friends: Involvement of the Innate Immune System in Tumor Progression.

Castano, Maria; (...); Gilabert-Estelles, Juan

Editorial Material. 10.3390/ijms24087604. 2023

  • Open Access.

Novel contributions of neutrophils in the pathogenesis of abdominal aortic aneurysm, the role of neutrophil extracellular traps: A systematic review

Plana, E; (...); Miralles, M

Review. 10.1016/j.thromres.2020.07.039. 2020


PLASMATIC DNA STIMULATES THE GENERATION OF IN VITRO THROMBIN EVEN IN THE ABSENCE OF EXTRINSIC TISSUE FACTOR AND CAN BE REVERSED WITH DNA'S

Fernandez-Pardo, A.; (...); Medina, P.

Meeting Abstract. 2019

  • Open Access.

Role of Syndecans in Ovarian Cancer: New Diagnostic and Prognostic Biomarkers and Potential Therapeutic Targets.

Oto, Julia; (...); Gotte, Martin

Article. 10.3390/cancers15123125. 2023

  • Open Access.

The Potential of Extracellular Microvesicle-microRNAs in Precapillary Pulmonary Hypertension.

Tura-Ceide, Olga; (...); Barbera, Joan Albert

Article. 10.1165/rcmb.2024-0282LE. 2025


Thrombospondins in human aortic aneurysms.

Plana, Emma; (...); Miralles, Manuel

Article. 10.1002/iub.2610. 2022


Urinary microRNAs: Looking for a New Tool in Diagnosis, Prognosis, and Monitoring of Renal Cancer

Oto, J; (...); Medina, P

Article. 10.1007/s11934-020-0962-9. 2020


Urine metabolomic analysis in clear cell and papillary renal cell carcinoma: A pilot study

Oto J; (...); Medina P

Article. 10.1016/j.jprot.2020.103723. 2020


VALIDATION OF A MODEL WITH COAGULATION-RELATED MARKERS FOR THE DIAGNOSIS OF PROSTHETIC JOINT INFECTION

Oto, J.; (...); Medina, P.

Meeting Abstract. 2019

  • Open Access.

Validation of urine p-cresol glucuronide as renal cell carcinoma non-invasive biomarker

Oto, Julia; (...); Medina, Pilar

Article. 10.1016/j.jprot.2024.105357. 2025


Identificación De Nuevas Moléculas Con Actividad Anticoagulante Y/O Citoprotectora En La Vía De La Proteína C: Explorando Su Utilidad Clínica.

Autor/es: Álvaro Fernández Pardo

Tesis Doctoral

Director/s: PILAR MEDINA BADENES; Silvia Navarro Rosales; Luís Andrés Ramón Núñez


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