Emerging biomarkers and targeted therapies in acute myeloid leukemia. combining omics data with machine learning. (nuevos biomarcadores y terapias dirigidas en la leucemia mieloide aguda. combinación de datos ómicos con machine learning).

Datos básicos

Protocolo:
PI19/00730
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2020
Año de finalización:
2023
PI BIOMÉDICA NACIONAL Finan. Competitiva Pública 148.104,00 €

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

INSTITUTO DE SALUD CARLOS III

Resultados del Ensayo Clínico


A Cutting-Edge Bioinformatics Tool for Neoantigen Identification in Unpaired RNA-Seq Samples of AML

Perez Miguez, Carlos; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2024-201407. 2024


A High Percentage of DNAM-1+and Low Percentage of Tactile plus NK Cells at Diagnosis Correlate with Complete Response and Survival in AML: A Sub-Analysis of the Ven-a-Qui Pethema Trial

Bergua Burgues, Juan Miguel; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-189676. 2023

  • Open Access.

A phase 2, multicenter, clinical trial of CPX-351 in older patients with secondary or high-risk acute myeloid leukemia: PETHEMA-LAMVYX.

Rodríguez-Arbolí E; (...); Montesinos P

Article. 10.1002/cncr.35618. 2024

  • Open Access.

A phase 3 trial of azacitidine versus a semi-intensive fludarabine and cytarabine schedule in older patients with untreated acute myeloid leukemia.

Vives S; (...); PETHEMA Group

Article. 10.1002/cncr.33403. 2021


A phase I trial of selinexor plus FLAG-Ida for the treatment of refractory/relapsed adult acute myeloid leukemia patients

Sanchez, MPM; (...); Montesinos, P

Article. 10.1007/s00277-021-04542-8. 2021


A predictive model for prostate cancer incorporating PSA molecular forms and age.

Oto J; (...); Navarro S

Article. 10.1038/s41598-020-58836-4. 2020

  • Open Access.

Acute leukemia arising from myeloproliferative or myelodysplastic/myeloproliferative neoplasms: A series of 372 patients from the PETHEMA AML registry.

Hernandez-Boluda, Juan-Carlos; (...); PETHEMA group

Article. 10.1016/j.leukres.2022.106821. 2022


Acute myeloid leukemia with inv(3)(q21.3q26.2)/t(3;3)(q21.3;q26.2): Study of 61 patients treated with intensive protocols

Sitges, M; (...); Vives, S

Article. 10.1111/ejh.13417. 2020


Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene

Liquori A; (...); Cervera J

Review. 10.3390/cancers12030624. 2020

  • Open Access.

Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene (vol 12, 624, 2020)

Liquori A; (...); Cervera J

Article. 10.3390/cancers13143440. 2021

  • Open Access.

AN INCREASE OF FREE FATTY ACIDS ON PATIENTS STARTING PERITONEAL DIALYSIS SUGGESTS AN INCREASED CARDIOVASCULAR RISK BEYOND CLASSICAL DYSLIPIDEMIA BIOMARKERS

Lopez Romero, Luis Carlos; (...); Julia Hernández Lluesa

Meeting Abstract. 2022


Analysis of SNP Array Abnormalities in Patients with DE NOVO Acute Myeloid Leukemia with Normal Karyotype

Ibanez, M; (...); Cervera, J

Article. 10.1038/s41598-020-61589-9. 2020

  • Open Access.

Atypical B-Cell Acute Lymphoblastic Leukemia with iAMP21 in the Context of Constitutional Ring Chromosome 21: A Case Report and Review of the Genetic Insights.

Gil, Jose Vicente; (...); Llop, Marta

Article. 10.3390/ijms26010357. 2025

  • Open Access.

Author Correction: Brain areas lipidomics in female transgenic mouse model of Alzheimer's disease.

Ferré-González L; (...); Cháfer-Pericás C

Correction. 10.1038/s41598-024-52528-z. 2024

  • Open Access.

Author Correction: Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA.

Sánchez R; (...); Martínez-López J

Correction. 10.1038/s41598-024-57570-5. 2024

  • Open Access.

Autologous or allogeneic hematopoietic stem cell transplantation as front-line treatment for adult secondary acute myeloid leukemia patients: the PETHEMA registry experience.

Serrano, Josefina; (...); Montesinos, Pau

Article. 10.1016/j.jtct.2025.02.011. 2025


Azacitidine or Decitabine Monotherapy for the Treatment of AML: A Comparative Systematic Review and Meta-Analysis

Saiz-Rodriguez, M; (...); Montesinos, P

Meeting Abstract. 2021


Brain areas lipidomics in female transgenic mouse model of Alzheimer's disease

Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo

Article. 10.1038/s41598-024-51463-3. 2024

  • Open Access.

Cis-Acting Splicing-Associated Variants Can Redefine the Molecular Signature of Genes Commonly Mutated in Acute Myeloid Leukemia

Morote-Faubel, Mireya; (...); Cervera, Jose

Meeting Abstract. 10.1182/blood-2023-177571. 2023

  • Open Access.

Clonal Evolution Analysis Using Next Generation Sequencing (NGS) Panel in a Cohort of 3,025 Patients With Acute Myeloid Leukemia (AML)

Colmenares, Rafael; (...); Montesinos, Pau

Meeting Abstract. 2023


Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group

Sargas, Claudia; (...); Montesinos, Pau

Article. 10.1038/s41408-023-00835-5. 2023

  • Open Access.

Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach.

Gil, Jose Vicente; (...); Barragan, Eva

Article. 10.3389/fmolb.2024.1362081. 2024

  • Open Access.

Comprehensive Metabolomic Profiling in Adults with X-Linked Hypophosphatemia: A Case-Control Study

Lopez-Romero, Luis Carlos; (...); Hernandez-Jaras, Julio

Article. 10.3390/biomedicines13010022. 2025


Conventional PCR Versus Next Generation Sequencing for Diagnosis of FLT3, IDH and NPM1 Mutations in Acute Myeloid Leukemia: Interim Analysis of the PCR-LMA Protocol of the Pethema Group

Boluda, Blanca; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-160136. 2022

  • Open Access.

Corrigendum to "Performance of prognostic scoring systems in elderly patients with acute myeloid leukaemia on intensive chemotherapy: A PETHEMA registry study" [Leuk. Res. 92 (March) (2020) 106352].

Rodríguez-Medina C; (...); Montesinos P

Correction. 10.1016/j.leukres.2020.106388. 2020


Cytogenetic Assessment and Risk Stratification in Myelofibrosis with Optical Genome Mapping.

Diaz-Gonzalez, Alvaro; (...); Such, Esperanza

Article. 10.3390/cancers15113039. 2023

  • Open Access.

Changes in lipid metabolism driven by steroid signalling modulate proteostasis in C. elegans.

Gomez-Escribano, Ana P.; (...); Vazquez-Manrique, Rafael P.

Article. 10.15252/embr.202255556. 2023

  • Open Access.

Changes in sleep-disordered breathing from the acute to the stable phase of pulmonary embolism and impact of right ventricular dysfunction: preliminary findings of ESAET study

Ortega, AG; (...); Martinez-Garcia, MA

Meeting Abstract. 10.1183/13993003.congress-2020.4974. 2020


Characteristics and Outcomes of Adult Patients in the PETHEMA Registry with Relapsed or Refractory FLT3-ITD Mutation-Positive Acute Myeloid Leukemia.

Martinez-Cuadron, David; (...); On Behalf Of The Pethema Group

Article. 10.3390/cancers14112817. 2022

  • Open Access.

Characteristics, clinical outcomes, and risk factors of SARS-COV-2 infection in adult acute myeloid leukemia patients: experience of the PETHEMA group

Palanques-Pastor, Tomas; (...); Montesinos, Pau

Article. 10.1080/10428194.2021.1948031. 2021


Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers

Perales-Chorda C; (...); de Rojas, DHF

Article. 10.1111/cea.13991. 2021

  • Open Access.

CHARACTERIZATION OF THE GENOMIC AND TRANSCRIPTOMIC PROFILE OF THE ACUTE MYELOID LEUKEMIA (AML) SUBGROUP "CHROMATIN-SPLICEOSOME"

Alessandro, Liquori; (...); Zamora Jose, Cervera

Meeting Abstract. 2020

  • Open Access.

Characterization ofFLT3-ITD(mut)acute myeloid leukemia: molecular profiling of leukemic precursor cells

Travaglini, S; (...); Ottone, T

Article. 10.1038/s41408-020-00352-9. 2020

  • Open Access.

Design and Validation of a Custom Next-Generation Sequencing Panel in Pediatric Acute Lymphoblastic Leukemia.

Gil, Jose Vicente; (...); Barragan, Eva

Article. 10.3390/ijms24054440. 2023

  • Open Access.

DESIGN AND VALIDATION OF AN ACUTE LYMPHOBLASTIC LEUKEMIA-TARGETED NEXT-GENERATION SEQUENCING PANEL

Gil, JV.; (...); Llop, M.

Meeting Abstract. 2023


Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA.

Sanchez, Ricardo; (...); Martinez-Lopez, Joaquin

Article. 10.1038/s41598-022-17271-3. 2022

  • Open Access.

Do NPM1 and FLT3-ITD mutations modify prognosis in patients treated with non-intensive regimens?

Suárez EU; (...); Montesinos P

Article. 10.1007/s00277-024-05840-7. 2024


Early Metabolomic Profiling as a Predictor of Renal Function Six Months After Kidney Transplantation

Viejo-Boyano, Iris; (...); Hernandez-Jaras, Julio

Article. 10.3390/biomedicines12112424. 2024

  • Open Access.

Effect of providing citrus pulp-integrated diet on fecal microbiota and serum and fecal metabolome shifts in crossbred pigs.

Belloumi, Dhekra; (...); Cerisuelo, Alba

Article. 10.1038/s41598-023-44741-z. 2023

  • Open Access.

Enhancing Cytogenetic Diagnostics: Incorporating Optical Genome Mapping in the Laboratory Routine

Diaz-Gonzalez, Alvaro; (...); Such, Esperanza

Meeting Abstract. 10.1182/blood-2023-180691. 2023

  • Open Access.

Evolution of the Genetic and Biological Studies Performed at Diagnosis in Patients with Acute Myeloid Leukemia Included in the Pethema Epidemiological Registry (REALMOL Study)

Labrador, Jorge; (...); Manuel Alonso-Dominguez, Juan

Meeting Abstract. 10.1182/blood-2022-163016. 2022

  • Open Access.

Evolving patterns and clinical outcome of genetic studies performed at diagnosis in acute myeloid leukemia patients: Real life data from the PETHEMA Registry.

Labrador, Jorge; (...); Montesinos, Pau

Article. 10.1002/cncr.35431. 2024

  • Open Access.

Evolving patterns of care and outcomes in relapsed/refractory FLT3 mutated acute myeloid leukemia adult patients.

Boluda B; (...); Montesinos P

Article. 10.1080/10428194.2021.1938031. 2021


Evolving treatment patterns and outcomes in older patients (=60 years) with AML: changing everything to change nothing?

Martínez-Cuadrón D; (...); Montesinos P

Article. 10.1038/s41375-020-01058-4. 2020


Exploring Potential Molecular Mechanisms of Drug Response in FLT3-ITD Negative AML Patients Treated with Quizartinib Vs Placebo Plus Standard Chemotherapy in the Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180710. 2023


Extracorporeal photopheresis vs standard therapies for steroid-refractory chronic graft-vs-host disease: Pharmacoeconomic assessment of hospital resource use in Spain.

Boluda, Blanca; (...); Montesinos, Pau

Article. 10.1002/jca.21901. 2021

  • Open Access.

FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients-efficacy and microbiologic safety

Moreno, Ainhoa Fernandez; (...); Bernal, Teresa

Article. 10.1186/s13063-023-07702-5. 2023

  • Open Access.

FUNCTIONAL RECLASSIFICATION THROUGH MINIGENE TESTS OF MISSENSE VARIANTS WITH EFFECT ON SPLICING IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

Morote-Faubel, Mireya; (...); Cervera, Jose

Meeting Abstract. 2020

  • Open Access.

Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants.

Mannan A; (...); Aljurf M

Article. 10.1016/j.hemonc.2020.05.007. 2020

  • Open Access.

GERMLINE PREDISPOSITION TO MYELOID MALIGNANCIES IN A CONSECUTIVE COHORT OF 183 PATIENTS

Santiago, M.; (...); Cervera-Zamora, J.

Meeting Abstract. 10.1016/j.leukres.2023.107247. 2023


Glucose 6 phosphate dehydrogenase overexpression rescues the loss of cognition in the double transgenic APP/PS1 mouse model of Alzheimer's disease

Correas, Angela G.; (...); Vina, Jose

Article. 10.1016/j.redox.2024.103242. 2024

  • Open Access.

Healthcare Resource Utilization among Patients between 60-75 Years with Secondary Acute Myeloid Leukemia Receiving Intensive Chemotherapy Induction: A Spanish Retrospective Observational Study

Solana-Altabella, Antonio; (...); Martinez-Cuadron, David

Article. 10.3390/cancers14081921. 2022

  • Open Access.

Healthcare resource utilization in adult patients with relapsed/refractory FLT3 mutated acute myeloid leukemia: A retrospective chart review from Spain.

Solana-Altabella A; (...); Montesinos P

Article. 10.1111/ejh.13604. 2021


Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia.

Vega-Garcia N; (...); Camós M

Article. 10.3390/jpm10040244. 2020

  • Open Access.

History of Acute Promyelocytic Leukemia.

Sanz MA, Barragán E

Article. 10.2991/chi.k.210703.001. 2021

  • Open Access.

Iadademstat in Combination with Azacitidine Generates Robust and Long Lasting Responses in AML Patients (ALICE Trial)

Salamero, Olga; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2021-152183. 2021

  • Open Access.

Iadademstat in combination with azacitidine in patients with newly diagnosed acute myeloid leukaemia (ALICE): an open-label, phase 2a dose-finding study.

Salamero, Olga; (...); Montesinos, Pau

Article. 10.1016/S2352-3026(24)00132-7. 2024


Identification of Leukemia-Associated Immunophenotypes by Databaseguided Flow Cytometry Provides a Highly Sensitive and Reproducible Strategy for the Study of Measurable Residual Disease in Acute Myeloblastic Leukemia

Pinero, Paula; (...); Tarin, Fabian

Article. 10.3390/cancers14164010. 2022

  • Open Access.

Identification of Novel microRNA Profiles Dysregulated in Plasma and Tissue of Abdominal Aortic Aneurysm Patients

Plana E; (...); Miralles M

Article. 10.3390/ijms21134600. 2020

  • Open Access.

Identifying prognostic gene panels in acute myeloid leukemia.

Sanchez-Garcia, Joaquin; (...); Montesinos, Pau

Article. 10.1080/17474086.2023.2193322. 2023


IMPACT OF ALLELIC STATUS OF TP53 MUTATIONS IN ACUTE MYELOID LEUKEMIA (AML)

Ibanez, Mariam; (...); Sanz, Guillermo

Meeting Abstract. 2020

  • Open Access.

Impact of combinations of single-nucleotide polymorphisms of anthracycline transporter genes upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia.

Megías-Vericat JE; (...); Montesinos P

Article. 10.1080/10428194.2020.1839650. 2020


Impact of FLT3-ITD Mutation Status and Its Ratio in a Cohort of 2901 Patients Undergoing Upfront Intensive Chemotherapy: A PETHEMA Registry Study.

Ayala, Rosa; (...); Montesinos, Pau

Article. 10.3390/cancers14235799. 2022

  • Open Access.

Improving the prediction of acute myeloid leukaemia outcomes by complementing mutational profiling with ex vivo chemosensitivity.

Onecha E; (...); Ayala R

Article. 10.1111/bjh.16432. 2020


IN VIVO MODELS TO STUDY THE COOPERATION BETWEEN SPLICING AND DNA METHYLATION IN MYELODYSPLASTIC SYNDROMES

Martinez-Valiente, Cristina; (...); Sanjuan-Pla, Alejandra

Meeting Abstract. 2020

  • Open Access.

Incidence and Risk Factors for Development of Cardiac Toxicity in Adult Patients with Newly Diagnosed Acute Myeloid Leukemia

Boluda, Blanca; (...); Montesinos, Pau

Article. 10.3390/cancers15082267. 2023

  • Open Access.

Increase of Neutrophil Activation Markers in Venous Thrombosis-Contribution of Circulating Activated Protein C

Martos L; (...); Medina P

Article. 10.3390/ijms21165651. 2020

  • Open Access.

Influence of polymorphisms in anthracyclines metabolism genes in the standard induction chemotherapy of acute myeloid leukemia.

Megías-Vericat JE; (...); Montesinos P

Article. 10.1097/FPC.0000000000000431. 2021


Interim Results from Clevo: A Non-Interventional Cohort Study Investigating the Clonal Evolution of FMS-like Tyrosine Kinase 3 (FLT3) Mutations during Disease Progression in Patients with Acute Myeloid Leukemia

Papayannidis, Cristina; (...); Vyas, Paresh

Meeting Abstract. 10.1182/blood-2022-156296. 2022


ladademstat Combination with Azacitidine Is a Safe and Effective Treatment in First Line Acute Myeloid Leukemia. Final Results of the Alice Trial

Salamero, Olga; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-168945. 2022

  • Open Access.

LipidMS 3.0: an R-package and a web-based tool for LC-MS/MS data processing and lipid annotation.

Alcoriza-Balaguer MI; (...); Lahoz, Agustin

Article. 10.1093/bioinformatics/btac581. 2022

  • Open Access.

Management of hyperleukocytosis and impact of leukapheresis among patients with acute myeloid leukemia (AML) on short- and long-term clinical outcomes: a large, retrospective, multicenter, international study.

Stahl M; (...); Zeidan AM

Article. 10.1038/s41375-020-0783-3. 2020

  • Open Access.

Metabolic changes in a food allergy anaphylaxis model allow predicting IgE or non-IgE-mediated drug anaphylaxis patients

Perales Chorda, C.; (...); Villasenor, A.

Meeting Abstract. 2020


Metabolic Pathways Affected in Patients Undergoing Hemodialysis and Their Relationship with Inflammation.

Peris-Fernández M; (...); Hernández-Jaras J

Article. 10.3390/ijms25179364. 2024

  • Open Access.

Metabolomics of Plasma in XLH Patients with Arterial Hypertension: New Insights into the Underlying Mechanisms

Lopez-Romero, Luis Carlos; (...); Hernandez-Jaras, Julio

Article. 10.3390/ijms25063545. 2024

  • Open Access.

microRNAs and Markers of Neutrophil Activation as Predictors of Early Incidental Post-Surgical Pulmonary Embolism in Patients with Intracranial Tumors

Oto, J; (...); Medina, P

Article. 10.3390/cancers12061536. 2020

  • Open Access.

MicroRNAs and Neutrophil Activation Markers Predict Venous Thrombosis in Pancreatic Ductal Adenocarcinoma and Distal Extrahepatic Cholangiocarcinoma.

Oto J; (...); Medina P

Article. 10.3390/ijms21030840. 2020

  • Open Access.

Mild Muscle Mitochondrial Fusion Distress Extends Drosophila Lifespan through an Early and Systemic Metabolome Reorganization.

Tapia A; (...); Galindo MI

Article. 10.3390/ijms222212133. 2021

  • Open Access.

MODELING OF IDH2 GENE MUTATIONS IN THE CAENORHABDITIS ELEGANS ORGANISM. DEVELOPMENT OF A NEW STUDY MODEL

Gonzalez-Romero, E.; (...); Cervera-Zamora, J.

Meeting Abstract. 2021

  • Open Access.

Molecular Landscape and Validation of New Genomic Classification in 2668 Adult AML Patients: Real Life Data from the PETHEMA Registry.

Sargas, Claudia; (...); On Behalf Of Pethema Group

Article. 10.3390/cancers15020438. 2023

  • Open Access.

Networking for advanced molecular diagnosis in acute myeloid leukemia patients is possible: the PETHEMA NGS-AML project.

Sargas C; (...); Montesinos P

Article. 10.3324/haematol.2020.263806. 2021

  • Open Access.

No Evidence that CD33 rs12459419 Polymorphism Predicts Gemtuzumab Ozogamicin Response in Consolidation Treatment of Acute Myeloid Leukemia Patients: Experience of the PETHEMA Group.

Castano-Bonilla, Tamara; (...); Montesinos, Pau

Article. 10.1155/2022/3132941. 2022

  • Open Access.

Non-Invasive Infections Diagnosis in Lung Transplant Recipients in Exhaled Breath Condensate

Ibanez-Martinez, E.; (...); Sole-Jover, A.

Meeting Abstract. 2021


Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Article. 10.3324/haematol.2022.282506. 2024

  • Open Access.

Performance of prognostic scoring systems in elderly patients with acute myeloid leukaemia on intensive chemotherapy: A PETHEMA registry study

Rodriguez-Medina, C; (...); Fernandez, PM

Article. 10.1016/j.leukres.2020.106352. 2020


Pethema NGS-AML Project. Final Analysis and Clinical Validation of New Genomic Classifications

Sargas, Claudia; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-166639. 2022

  • Open Access.

Plasma lipidomics in early APP/PS1 female mouse model and its relationship with brain: Is it affected by the estrous cycle?

Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo

Article. 10.1186/s13195-024-01549-x. 2024

  • Open Access.

PLZF-RAR(alpha), NPM1-RAR(alpha), and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review

Sobas, M; (...); Montesinos, P

Review. 10.3390/cancers12051313. 2020

  • Open Access.

Practical Considerations for Treatment of Relapsed/Refractory FLT3-ITD Acute Myeloid Leukaemia with Quizartinib: Illustrative Case Reports.

Martínez-Cuadrón D; (...); Montesinos P

Article. 10.1007/s40261-019-00881-7. 2020

  • Open Access.

Prognostic Impact of NPM1 and FLT3-ITD Mutations in Patients Treated with Non-Intensive Regimens: A Pethema Registry Study

Uriel Suarez, Edwin; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-167365. 2022

  • Open Access.

Prognostic significance of FLT3-ITD length in AML patients treated with intensive regimens.

Castaño-Bonilla T; (...); Montesinos, P

Article. 10.1038/s41598-021-00050-x. 2021

  • Open Access.

PROPOSED MOLECULAR CLASSIFICATION OF ACUTE MYELOBLASTIC LEUKEMIA (AML) BASED ON SPLICING EVENTS

Liquori, A.; (...); Cervera Zamora, J.

Meeting Abstract. 2021

  • Open Access.

REMOVAL OF GERMINAL LINE MUTATIONS IN PATIENTS WITH MDS AND AML: WHO SHOULD BE PERFORMED?

Santiago, Marta; (...); Cervera, Jose

Meeting Abstract. 2020


Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial

Roca; (...); Lahoz

Review. 2021


Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial.

Roca M; (...); Lahoz A

Article. 10.1016/j.aca.2020.12.025. 2021


SEQUENCING OF THE EXOME IN THE RECALLING OR REFRACTORY AML

Simarro Claudia, Sargas; (...); Eva, Barragan

Meeting Abstract. 2021

  • Open Access.

Sleep Duration and Cutaneous Melanoma Aggressiveness. A Prospective Observational Study in 443 Patients.

Gómez Olivas JD; (...); Martinez-García MA

Case Reports. 10.1016/j.arbr.2020.10.017. 2021


STUDY OF TRANSCRIPTIONAL DIFFERENCES BETWEEN THE IDH2 R140 AND R172 MUTATIONS BY MEANS OF MODELING IN THE ORGANISM CAENORHABDITIS ELEGANS

Gonzalez, Romero Elisa; (...); Cervera, Jose Vicente

Meeting Abstract. 2020

  • Open Access.

The FLT3-like Gene Expression Signature Predicts Response to Quizartinib in Wild-Type FLT3 Acute Myeloid Leukemia: An Analysis of the Pethema Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180482. 2023

  • Open Access.

The metabolomic differential plasma profile between dialysates. Pursuing to understand the mechanisms of citrate dialysate clinical benefits.

Broseta, Jose Jesus; (...); Hernandez-Jaras, Julio

Article. 10.3389/fphys.2022.1013335. 2022

  • Open Access.

The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Trial

Ayala, R; (...); Montesinos, P

Article. 10.3390/cancers13102458. 2021

  • Open Access.

Treatment Outcomes in Unfit Patients with Newly Acute Myeloid Leukemia According to IDH1 Mutational Status: Real World Evidence from the Pethema Epidemiologic Registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-189800. 2023

  • Open Access.

Treatment patterns and outcomes in secondary acute myeloid leukemia arising after hypomethylating agents: PETHEMA registry study.

Lloret-Madrid, Pilar; (...); Montesinos, Pau

Article. 10.1002/cncr.35696. 2025


Treatment patterns and outcomes of 2310 patients with secondary acute myeloid leukemia: a PETHEMA registry study.

Martínez-Cuadrón D; (...); Montesinos P

Article. 10.1182/bloodadvances.2021005335. 2022

  • Open Access.

TYK2 Variants in B-Acute Lymphoblastic Leukaemia.

Turrubiartes-Martínez E; (...); Fernández-Ruiz E

Article. 10.3390/genes11121434. 2020

  • Open Access.

Tyrosine kinase inhibitors for acute myeloid leukemia: A step toward disease control?

Megías-Vericat JE; (...); Montesinos P

Review. 10.1016/j.blre.2020.100675. 2020


Uremic Toxins and Inflammation: Metabolic Pathways Affected in Non-Dialysis-Dependent Stage 5 Chronic Kidney Disease

Peris-Fernandez, Maria; (...); Hernandez-Jaras, Julio

Article. 10.3390/biomedicines12030607. 2024

  • Open Access.

Urinary microRNAs: Looking for a New Tool in Diagnosis, Prognosis, and Monitoring of Renal Cancer

Oto, J; (...); Medina, P

Article. 10.1007/s11934-020-0962-9. 2020


Urine metabolomic analysis in clear cell and papillary renal cell carcinoma: A pilot study

Oto J; (...); Medina P

Article. 10.1016/j.jprot.2020.103723. 2020


Use of Azacitidine or Decitabine for the Up-Front Setting in Acute Myeloid Leukaemia: A Systematic Review and Meta-Analysis.

Saiz-Rodriguez, M; (...); Montesinos, P

Article. 10.3390/cancers13225677. 2021

  • Open Access.

VALIDATION OF FREQUENT SPLICING EVENTS IN ACUTE MYELOID LEUKEMIA WITH POTENTIAL TO GENERATE NEOANTIGENS

Beatriz, Fernandez-Blanco; (...); Jose Vicente, Cervera Zamora

Meeting Abstract. 2021

  • Open Access.

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Validation of urine p-cresol glucuronide as renal cell carcinoma non-invasive biomarker

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Article. 10.1016/j.jprot.2024.105357. 2025


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