Desarrollo de nanoterapias anti-inflamatorias en retinosis pigmentaria.

Datos básicos

Código:
PI18/00252
Protocolo:
PI18/00252
EUDRACT:
NCT:
Centro:
Dotación:
212.053,00 €
Año de incio:
2019
Año de finalización:
2020
PI BIOMÉDICA NACIONAL Finan. Competitiva Pública

Objetivos del proyecto

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Documentos

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Participantes

Grupos

Financiadores - Promotores

INSTITUTO DE SALUD CARLOS III

Resultados del Ensayo Clínico


Colorectal cancer: pharmacogenetics support for the correct drug prescription

Olivera, G; (...); Alino, SF

Review. 10.2217/pgs-2019-0041. 2019


Concomitant mutations in inherited retinal dystrophies: why the reproductive and therapeutic counselling should be addressed cautiously.

Rodriguez-Munoz, Ana; (...); Millan, Jose

Article. 10.1097/IAE.0000000000003103. 2021

  • Open Access.

Decreased DNA hydroxymethylation and increased DNA demethylation are associated with high antioxidant response in systemic lupus erythematosus patients.

Fragío Gil JJ; (...); Román Ivorra JA

Case Reports. 10.1016/j.medcli.2020.10.023. 2021


Do Intestinal Unicellular Parasites Have a Role in the Inflammatory and Redox Status among the Severely Obese?

Caudet, Jana; (...); Merino-Torres, Juan F

Article. 10.3390/antiox11112090. 2022

  • Open Access.

Efficacy of interleukin 10 gene hydrofection in pig liver vascular isolated 'in vivo' by surgical procedure with interest in liver transplantation.

Sendra L; (...); Aliño SF

Article. 10.1371/journal.pone.0224568. 2019

  • Open Access.

Expanding the clinical and molecular heterogeneity of nonsyndromic inherited retinal dystrophies.

Rodríguez-Muñoz A; (...); Millán JM

Article. 10.1016/j.jmoldx.2020.01.003. 2020

  • Open Access.

Foxp3 Silencing with Antisense Oligonucleotide Improves Immunogenicity of an Adjuvanted Recombinant Vaccine against Sporothrix schenckii

Batista-Duharte, A; (...); Alino, SF

Article. 10.3390/ijms22073470. 2021

  • Open Access.

Gold Nanoparticle-Assisted Virus Formation by Means of the Delivery of an Oncolytic Adenovirus Genome

Sendra, L; (...); Alino, SF

Article. 10.3390/nano10061183. 2020

  • Open Access.

Heterozygous pathogenic variants in GLI1 are a common finding in isolated postaxial polydactyly A/B.

Palencia-Campos A; (...); Ruiz-Pérez VL

Article. 10.1002/humu.23921. 2020


In vitro assessment of the photo(geno)toxicity associated with Lapatinib, a Tyrosine Kinase inhibitor.

Garcia-Lainez, Guillermo; (...); Andreu, Inmaculada

Article. 10.1007/s00204-020-02880-6. 2021


Intravitreal administration of adalimumab delays retinal degeneration in rd10 mice.

Olivares-González L; (...); Rodrigo R

Article. 10.1096/fj.202000044RR. 2020

  • Open Access.

Macular retinal vessel density assessment of the superficial, deep plexus and choriocapillaris in patients with retinitis pigmentosa and in healthy individuals using SS-OCT Angiography

Valencia-Perez, C; (...); Millan, JM

Meeting Abstract. 2019

  • Open Access.

Mitochondrial DNA Replacement Techniques to Prevent Human Mitochondrial Diseases.

Sendra L; (...); Aliño SF

Review. 10.3390/ijms22020551. 2021

  • Open Access.

MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients

Olivera, GG; (...); Herrero, MJ

Article. 10.3390/ijms21082714. 2020

  • Open Access.

Multicompartmental Lipopolyplex as Vehicle for Antigens and Genes Delivery in Vaccine Formulations.

Sanmartín I; (...); Aliño SF

Article. 10.3390/pharmaceutics13020281. 2021

  • Open Access.

Nutraceutical Supplementation Ameliorates Visual Function, Retinal Degeneration, and Redox Status in rd10 Mice

Olivares-Gonzalez, Lorena; (...); Rodrigo, Regina

Article. 10.3390/antiox10071033. 2021

  • Open Access.

NUTRARET: Effect of 2-Year Nutraceutical Supplementation on Redox Status and Visual Function of Patients With Retinitis Pigmentosa: A Randomized, Double-Blind, Placebo-Controlled Trial

Olivares-Gonzalez, Lorena; (...); Rodrigo, Regina

Article. 10.3389/fnut.2022.847910. 2022

  • Open Access.

Oxidative Stress, a Crossroad between Rare Diseases and Neurodegeneration

Espinos, C; (...); Pallardo, FV

Review. 10.3390/antiox9040313. 2020

  • Open Access.

Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.

Urtasun, Andrea; (...); Herrero, Maria Jose

Article. 10.3390/cancers15051424. 2023

  • Open Access.

Pharmacogene Variants Associated with Liver Transplant in a Twelve-Year Clinical Follow-Up.

Sendra L; (...); Aliño SF

Article. 10.3390/pharmaceutics14020354. 2022

  • Open Access.

Pharmacogenetics implementation in the clinics: information and guidelines for germline variants

Olivera, Gladys; (...); Alino, Salvador F.

Review. 10.20517/cdr.2018.25. 2019

  • Open Access.

Pharmacogenetics in Neuroblastoma: What Can Already Be Clinically Implemented and What Is Coming Next?

Olivera, GG; (...); Herrero, MJ

Review. 10.3390/ijms22189815. 2021

  • Open Access.

Pharmacogenetics of colorectal cancer in a third-level hospital in Valencia.

Comes-Raga A; (...); Herrero Cervera MJ

Article. 10.1515/almed-2024-0146. 2024

  • Open Access.

Redox Status in Retinitis Pigmentosa.

Olivares-González L; (...); Rodrigo R

Article. 10.1007/978-3-031-27681-1_65. 2023


Redox Status, Dose and Antioxidant Intake in Healthcare Workers Occupationally Exposed to Ionizing Radiation

Sebastia, N; (...); Rodrigo, R

Article. 10.3390/antiox9090778. 2020

  • Open Access.

Retinal Inflammation, Cell Death and Inherited Retinal Dystrophies.

Olivares-Gonzalez, Lorena; (...); Rodrigo, Regina

Review. 10.3390/ijms22042096. 2021

  • Open Access.

Starkeya nomas sp. nov., a prosthecate and budding bacterium isolated from an immunocompromized patient.

Sahuquillo-Arce JM; (...); López-Hontangas JL

Article. 10.1099/ijsem.0.005805. 2023


The Golgi complex of dopaminergic enteric neurons is fragmented in a hemiparkinsonian rat model

Cara-Esteban, Mireia; (...); Tomas, Monica

Article. 10.1002/jemt.24442. 2024

  • Open Access.

The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery

Esteban-Medina, Marina; (...); Pena-Chilet, Maria

Article. 10.1186/s12967-024-04911-7. 2024

  • Open Access.

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