GENÓMICA COMPARADA MICROBIANA

Datos básicos

Código:
2015_0508_CPC_TORMO
Dotación:
Año inicial:
2015
Año final:
2017
PROYECTO

Objetivos del proyecto

DENEGADO

Documentos

  • No hay documentos

Participantes

Grupos

Resultados del Proyecto


A Cutting-Edge Bioinformatics Tool for Neoantigen Identification in Unpaired RNA-Seq Samples of AML

Perez Miguez, Carlos; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2024-201407. 2024


A multihost bacterial pathogen overcomes continuous population bottlenecks to adapt to new host species

Bacigalupe, R; (...); Fitzgerald, JR

Article. 10.1126/sciadv.aax0063. 2019

  • Open Access.

An ex vivo cystic fibrosis model recapitulates key clinical aspects of chronic Staphylococcus aureus infection.

Sweeney E; (...); Harrison F

Article. 10.1099/mic.0.000987. 2021

  • Open Access.

Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of e-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier.

Guzel Kaya G; (...); Martínez-Máñez R

Article. 10.3390/pharmaceutics12111126. 2020

  • Open Access.

Aptamer-Capped nanoporous anodic alumina for Staphylococcus aureus detection

Pla, L; (...); Martinez-Manez, R

Article. 10.1016/j.snb.2020.128281. 2020


Autologous or allogeneic hematopoietic stem cell transplantation as front-line treatment for adult secondary acute myeloid leukemia patients: the PETHEMA registry experience.

Serrano, Josefina; (...); Montesinos, Pau

Article. 10.1016/j.jtct.2025.02.011. 2025


Climate change, animals, and Candida auris: insights into the ecological niche of a new species from a one health approach.

Garcia-Bustos, Victor; (...); Peman, Javier

Article. 10.1016/j.cmi.2023.03.016. 2023

  • Open Access.

Clinical and biological significance of isolated Y chromosome loss in myelodysplastic syndromes and chronic myelomonocytic leukemia. A report from the Spanish MDS Group

Nomdedeu, M; (...); Spanish MDS Group

Article. 10.1016/j.leukres.2017.10.011. 2017


Clonal Evolution Analysis Using Next Generation Sequencing (NGS) Panel in a Cohort of 3,025 Patients With Acute Myeloid Leukemia (AML)

Colmenares, Rafael; (...); Montesinos, Pau

Meeting Abstract. 2023


Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group

Sargas, Claudia; (...); Montesinos, Pau

Article. 10.1038/s41408-023-00835-5. 2023

  • Open Access.

Considering Bone Marrow Blasts From Nonerythroid Cellularity Improves the Prognostic Evaluation of Myelodysplastic Syndromes

Arenillas L; (...); Florensa L

Article. 10.1200/JCO.2016.66.9705. 2016


Conventional PCR Versus Next Generation Sequencing for Diagnosis of FLT3, IDH and NPM1 Mutations in Acute Myeloid Leukemia: Interim Analysis of the PCR-LMA Protocol of the Pethema Group

Boluda, Blanca; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-160136. 2022

  • Open Access.

Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization

Donderis, J; (...); Marina, A

Article. 10.1371/journal.ppat.1006581. 2017

  • Open Access.

Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols.

Sobas M; (...); PETHEMA, HOVON, PALG, GATLA cooperative groups

Article. 10.1111/ejh.13346. 2020

  • Open Access.

Characterization of the Differential Pathogenicity of Candida auris in a Galleria mellonella Infection Model.

Garcia-Bustos V; (...); Pemán J

Article. 10.1128/Spectrum.00013-21. 2021

  • Open Access.

Data-Driven Multiparameter Flow Cytometry (MFC) Classification of Blast Differentiation in Elderly Patients with Acute Myeloid Leukemia (AML)

Gonzalez, Carmen; (...); Paiva, Bruno

Meeting Abstract. 10.1182/blood-2023-180646. 2023

  • Open Access.

Early-Onset Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) without SF3B1 Mutations in Adults: Enrichment with Germline Variants in Genes Responsible for Congenital Sideroblastic Anemias

Jauregui, Sandra Novoa; (...); Jerez, Andres

Meeting Abstract. 10.1182/blood-2023-185836. 2023

  • Open Access.

Enhanced Antibacterial Activity through Silver Nanoparticles Deposited onto Carboxylated Graphene Oxide Surface

Barjola, Arturo; (...); Gimenez, Enrique

Article. 10.3390/nano12121949. 2022

  • Open Access.

Erythroleukemia shares biological features and outcome with myelodysplastic syndromes with excess blasts: a rationale for its inclusion into future classifications of myelodysplastic syndromes

Calvo X; (...); Florensa L

Article. 10.1038/modpathol.2016.146. 2016

  • Open Access.

Essential Topics for the Regulatory Consideration of Phages as Clinically Valuable Therapeutic Agents: A Perspective from Spain

Vazquez, Roberto; (...); Garcia, Pilar

Review. 10.3390/microorganisms10040717. 2022

  • Open Access.

Evolution of the Genetic and Biological Studies Performed at Diagnosis in Patients with Acute Myeloid Leukemia Included in the Pethema Epidemiological Registry (REALMOL Study)

Labrador, Jorge; (...); Manuel Alonso-Dominguez, Juan

Meeting Abstract. 10.1182/blood-2022-163016. 2022

  • Open Access.

Evolving patterns and clinical outcome of genetic studies performed at diagnosis in acute myeloid leukemia patients: Real life data from the PETHEMA Registry.

Labrador, Jorge; (...); Montesinos, Pau

Article. 10.1002/cncr.35431. 2024

  • Open Access.

Exploring Potential Molecular Mechanisms of Drug Response in FLT3-ITD Negative AML Patients Treated with Quizartinib Vs Placebo Plus Standard Chemotherapy in the Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180710. 2023


FREQUENCY AND CLINICAL IMPACT OF CDKN2A/B GENE LOCUS IN AN ADULT T-ALL COHORT OF PATIENTS ENROLLED IN THE SPANISH PETHEMA GROUP PROTOCOLS

Genesca, E; (...); Ribera, JM

Meeting Abstract. 2017

  • Open Access.

Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials.

Gonzalez-Gil, Celia; (...); Genesca, Eulalia

Article. 10.3324/haematol.2022.281196. 2023

  • Open Access.

Host-pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella

Garcia-Bustos, Victor; (...); Ruiz-Sauri, Amparo

Article. 10.1080/22221751.2021.2017756. 2022

  • Open Access.

Human papilloma virus DNA detection in clinical samples using fluorogenic probes based on oligonucleotide gated nanoporous anodic alumina films.

Hernández-Montoto A; (...); Martínez-Máñez R

Article. 10.1002/adhm.202203326. 2023

  • Open Access.

Impact of Center-related Characteristics and Macroeconomic Factors on the Outcome of Adult Patients With Acute Lymphoblastic Leukemia Treated With Pediatric-inspired Protocols.

Barba P; (...); Ribera JM

Article. 10.1097/HS9.0000000000000810. 2023

  • Open Access.

IMPACT OF CYTOGENETIC ABNORMALITIES DEFINING AML MYELODYSPLASIA-RELATED (WHO AND ICC 2022) IN FIRST LINE DECITABINE IN UNFIT AML PATIENTS

de la Fuente, Adolfo; (...); Tormo, Mar

Meeting Abstract. 2023


Impact of FLT3-ITD Mutation Status and Its Ratio in a Cohort of 2901 Patients Undergoing Upfront Intensive Chemotherapy: A PETHEMA Registry Study.

Ayala, Rosa; (...); Montesinos, Pau

Article. 10.3390/cancers14235799. 2022

  • Open Access.

Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.

Kayser, Sabine; (...); Schlenk, Richard F.

Article. 10.3324/haematol.2022.282127. 2023

  • Open Access.

In vitro activity of anidulafungin in combination with amphotericin B or voriconazole against biofilms of five Candida species

Valentín A; (...); Martínez JP

Article. 10.1093/jac/dkw316. 2016

  • Open Access.

Indolent Acute Myeloid Leukemia with Long Survival in Patients Treated with Best Supportive Care Only: A Pethema Registry Study

Labrador, Jorge; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-162591. 2022


INTENSIVE CHEMOTHERAPY VERSUS DECITABINE FIRST LINE LAM OVER 60 YEARS OLD

De la Fuente, A.; (...); Montesinos, P.

Meeting Abstract. 2019

  • Open Access.

Long-term antibacterial Ag plus -release biomaterials based on anodized Ti6Al4V and silver nanoparticles

Molina, J.; (...); Tormo-Mas, M. A.

Article. 10.1016/j.colsurfa.2023.132243. 2023


Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes.

Mosquera Orgueira, Adrian; (...); Valcarcel, David

Article. 10.1097/HS9.0000000000000961. 2023

  • Open Access.

Microstructural, mechanical, electrochemical, and biological studies of an electron beam melted Ti-6Al-4V alloy

Romero-Resendiz, L.; (...); Amigo-Borras, V

Article. 10.1016/j.mtcomm.2022.103337. 2022


Mobilisation Mechanism of Pathogenicity Islands by Endogenous Phages in Staphylococcus aureus clinical strains.

Cervera-Alamar, M; (...); Tormo-Mas, MA

Article. 10.1038/s41598-018-34918-2. 2018

  • Open Access.

Molecular identification of Candida auris by PCR amplification of species-specific GPI protein-encoding genes

Ruiz-Gaitan, AC; (...); de Groot PWJ

Article. 10.1016/j.ijmm.2018.06.014. 2018


Molecular Landscape and Validation of New Genomic Classification in 2668 Adult AML Patients: Real Life Data from the PETHEMA Registry.

Sargas, Claudia; (...); On Behalf Of Pethema Group

Article. 10.3390/cancers15020438. 2023

  • Open Access.

Molecular profiling refines minimal residual disease-based prognostic assessment in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia.

Ribera J; (...); Ribera JM

Article. 10.1002/gcc.22788. 2019


MUTATIONAL PROFILE IN PATIENTS DIAGNOSED WITH LOW-RISK SMD WITHOUT THE RINGED SIDEROBLASTS

Abaigar, M; (...); Campelo, MD

Meeting Abstract. 2018

  • Open Access.

Nanoemulsion Increases the Antifungal Activity of Amphotericin B against Four Candida auris Clades: In Vitro and In Vivo Assays.

Marena, Gabriel Davi; (...); Peman, Javier

Article. 10.3390/microorganisms11071626. 2023

  • Open Access.

NATIONAL EXPERIENCE WITH THE USE OF VENETOCLAX IN PATIENTS WITH RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA

Labrador, J.; (...); Montesinos, P.

Meeting Abstract. 2020

  • Open Access.

Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples.

Pla, Luis; (...); Santiago-Felipe, Sara

Article. 10.1080/22221751.2020.1870411. 2020

  • Open Access.

Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Article. 10.3324/haematol.2022.282506. 2024

  • Open Access.

Pethema NGS-AML Project. Final Analysis and Clinical Validation of New Genomic Classifications

Sargas, Claudia; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-166639. 2022

  • Open Access.

Prognostic impact of gene mutations in myelodysplastic syndromes with ring sideroblasts

Martin, I; (...); Sanz, G

Article. 10.1038/s41408-017-0016-9. 2017

  • Open Access.

Prognostic Impact of NPM1 and FLT3-ITD Mutations in Patients Treated with Non-Intensive Regimens: A Pethema Registry Study

Uriel Suarez, Edwin; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-167365. 2022

  • Open Access.

Radical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen

Yebra, G; (...); Penades, JR

Article. 10.1371/journal.ppat.1009606. 2021

  • Open Access.

Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged = 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

Requena, Gaspar Aspas; (...); Matinez-Cuadron, David

Meeting Abstract. 10.1182/blood-2023-190128. 2023

  • Open Access.

RESULTS OF THE TREATMENT OF LYMPHOBLASTIC LYMPHOMA WITH PROTOCOLS OF LYMPHOBLASTIC ACUTE LEUKEMIA OF PETHEMA GROUP

Sagues, M.; (...); Ribera, J. M.

Meeting Abstract. 2019

  • Open Access.

Salvage Therapy with Second-Generation Inhibitors for FLT3 Mutated Acute Myeloid Leukemia: A Real-World Study by the CETLAM and PETHEMA Groups

Vives, Susana; (...); PETHEMA Grp

Article. 10.3390/cancers16234028. 2024

  • Open Access.

SARS-CoV-2 N protein IgG antibody detection employing nanoporous anodized alumina: A rapid and selective alternative for identifying naturally infected individuals in populations vaccinated with spike protein (S)-based vaccines

Esteve-Sanchez, Yoel; (...); Climent, Estela

Article. 10.1016/j.snb.2024.136378. 2024

  • Open Access.

SARS-CoV-2-reactive antibody waning, booster effect and breakthrough SARS-CoV-2 infection in hematopoietic stem cell transplant and cell therapy recipients at one year after vaccination.

Pinana, Jose Luis; (...); Solano, Carlos

Article. 10.1038/s41409-023-01946-0. 2023

  • Open Access.

Selective and Sensitive Probe Based in Oligonucleotide-Capped Nanoporous Alumina for the Rapid Screening of Infection Produced by Candida albicans.

Ribes À; (...); Martinez-Manez, R

Article. 10.1021/acssensors.9b00169. 2019


Supervised Machine Learning Improves Risk Stratification in Newly Diagnosed Myelodysplastic Syndromes: An Analysis of the Spanish Group of Myelodysplastic Syndromes

Mosquera Orgueira, Adrian; (...); Valcarcel, David

Meeting Abstract. 10.1182/blood-2022-159429. 2022

  • Open Access.

The FLT3-like Gene Expression Signature Predicts Response to Quizartinib in Wild-Type FLT3 Acute Myeloid Leukemia: An Analysis of the Pethema Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180482. 2023

  • Open Access.

The Optimization of the Synthesis of Antibacterial Coatings on Ti6Al4V Coupons Obtained by Electron Beam Melting

Molina, Javier; (...); Bosch, Francisco

Article. 10.3390/met14080855. 2024

  • Open Access.

The poor prognosis of low hypodiploidy in adults with B-cell precursor acute lymphoblastic leukaemia is restricted to older adults and elderly patients

Ribera, J; (...); Ribera, JM

Article. 10.1111/bjh.15887. 2019

  • Open Access.

The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients.

Villar, Sara; (...); Montesinos, Pau

Article. 10.3389/fonc.2022.1054458. 2022

  • Open Access.

Transcriptional and Genomic Characterization of Measurable Residual Disease (MRD) Cells in Acute Myeloid Leukemia (AML)

Patricia Simoes, Catia; (...); Paiva, Bruno

Meeting Abstract. 10.1182/blood-2022-163159. 2022

  • Open Access.

Transcriptional and genomic characterization of measurable residual disease in acute myeloid leukaemia.

Simoes, Catia; (...); Montesinos, Pau

Letter. 10.1111/bjh.18815. 2023

  • Open Access.

Treatment Outcomes in Unfit Patients with Newly Acute Myeloid Leukemia According to IDH1 Mutational Status: Real World Evidence from the Pethema Epidemiologic Registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-189800. 2023

  • Open Access.

Treatment patterns and outcomes in secondary acute myeloid leukemia arising after hypomethylating agents: PETHEMA registry study.

Lloret-Madrid, Pilar; (...); Montesinos, Pau

Article. 10.1002/cncr.35696. 2025


VALIDATION OF PRECISION MEDICINE TEST FOR ACUTE MYELOID LEUKEMIA IN AN OBSERVATIONAL CLINICAL TRIAL

Montesinos, P; (...); Sanz, MA

Meeting Abstract. 2017

  • Open Access.

Validation of the Artificial Intelligence Prognostic Scoring System for Myelodysplastic Syndromes in chronic myelomonocytic leukaemia: A novel approach for improved risk stratification.

Mosquera Orgueira, Adrian; (...); Valcarcel, David

Article. 10.1111/bjh.19341. 2024

  • Open Access.

What Do We Know about Candida auris ? State of the Art, Knowledge Gaps, and Future Directions.

Garcia-Bustos V; (...); Pemán J

Article. 10.3390/microorganisms9102177. 2021

  • Open Access.

WHAT IS THE OUTCOME OF PATIENTS IN THE INTERMEDIATE IPSS-R SCORE GROUP? SPANISH APPROACH FOR BETTER STRATIFICATION WITH CLASSICAL TOOLS

Guijo, AMR; (...); Diez-Campelo, M

Meeting Abstract. 10.1016/S0145-2126(17)30374-0. 2017


WHO and ICC 2022 Cytogenetic Abnormalities Defining Acute Myelogenous Leukemia (AML) Myelodysplasia-Related in First-Line Decitabine in Unfit AML Patients

Ortiz Lopez, Alicia; (...); de la Fuente Burguera, Adolfo

Meeting Abstract. 2023


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