Idiopathic macular telangiectasia type 2: Prevalence and a morphometric and phenotypic study.

Autores de IIS La Fe

• Isabel Pascual Camps

  Autor

Participantes ajenos a IIS La Fe

• Bayon-Porras RM
• Plaza-Laguardia C
• Gallego-Pinazo R

Grupos

• Perinatología

  

  Leader

  Máximo Vento Torres

Abstract

OBJECTIVE: Type 2 idiopathic macular telangiectasia (MacTel2) is a rare retinal disease that has still not been well-defined. The aim of the present manuscript is to describe the clinical features by multimodal retinal imaging, to present the functional characteristics, and to estimate the prevalence of the disease. METHODS: A retrospective study was conducted on the 12 eyes of 6 patients with MacTel2. Fundus colour photographs, fundus autofluorescence, fluorescein angiography, optical coherence tomography (OCT), and OCT-angiography were performed and subsequently analysed. Visual acuity (VA) was prospectively recorded. The prevalence was established based on the patients referred to a specialised macular diseases unit. Minimum follow-up period was 18 months. RESULTS: Prevalence of MacTel 2 in our study was 0.12%. Clinical features were presented using multimodal retinal imaging. VA remained stable during follow-up. Three patients developed choroidal neovascularisation (CNV), requiring intravitreal treatment with antiangiogenic agents. CONCLUSIONS: The prevalence of the disease found was 0.12%. The study using multimodal imaging allows a more accurate diagnosis and follow-up of this pathology. The VA is maintained during the 18-month follow-up (P=.492). Patients who develop CNV and are treated with antiangiogenic agents appear to respond adequately to them. More studies are needed to establish these conclusions.

Keywords

• Angio-OCT; Angiografia; Angiography; Autofluorescence; Autofluorescencia; OCT; OCT angiography; Prevalence; Prevalencia; Telangiectasia macular; Type 2 macular telangiectasia