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Validation of a Spanish version of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Munoz, G
  • Buxo, M
  • de Gracia, J
  • Olveira, C
  • Giron, R
  • Polverino, E
  • Alvarez, A
  • Birring, SS
  • Vendrell, M

Grupos

Abstract

The Leicester Cough Questionnaire (LCQ) has been validated in non-cystic fibrosis bronchiectasis (NCFBC). The present study aimed to create and validate a Spanish version of the LCQ (LCQ-Sp) in NCFBC. The LCQ-Sp was developed following a standardized protocol. For reliability, we assessed internal consistency and the change in score over a 15-day period in stable state. For responsiveness, we assessed the change in scores between visit 1 and the first exacerbation. For validity, we evaluated convergent validity through correlation with the Saint George's Respiratory Questionnaire (SGRQ) and discriminant validity. Two hundred fifty-nine patients (118 mild bronchiectasis, 90 moderate bronchiectasis and 47 severe bronchiectasis) were included. Internal consistency was high for the total scoring and good for the different domains (Cronbach's : 0.86-0.91). The test-retest reliability shows an intraclass correlation coefficient of 0.87 for the total score. The mean LCQ-Sp score at visit 1 decreased at the beginning of an exacerbation (15.13 +/- 4.06 vs. 12.24 +/- 4.64; p < 0.001). The correlation between LCQ-Sp and SGRQ scores was -0.66 (p < 0.01). The differences in the LCQ-Sp total score between the different groups of severity were significant (p < 0.001). The LCQ-Sp discriminates disease severity, is responsive to change when faced with exacerbations and is reliable for use in bronchiectasis.

Datos de la publicación

ISSN/ISSNe:
1479-9723, 1479-9731

Chronic Respiratory Disease  SAGE PUBLICATIONS LTD

Tipo:
Article
Páginas:
128-136
PubMed:
26902541
Factor de Impacto:
0,867 SCImago ℠
Cuartil:
Q2 SCImago ℠

Citas Recibidas en Web of Science: 23

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Keywords

  • Bronchiectasis; cough; quality of life; patient-reported outcome; questionnaire

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