Portal de investigación
INFLAMMATORY BOWEL DISEASE Diagnostic Performance of the Simple Clinical Colitis Activity Index Self-Administered Online at Home by Patients With Ulcerative Colitis: CRONICA-UC Study
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Marin-Jimenez, I
- Domenech, E
- Riestra, S
- Gisbert, JP
- Calvet, X
- Cortes, X
- Iglesias, E
- Huguet, JM
- Taxonera, C
- Fernandez, R
- Carpio, D
- Gutierrez, A
- Guardiola, J
- Laria, LC
- Sicilia, B
- Bujanda, L
- Cea-Calvo, L
- Romero, C
- Rincon, O
- Julia, B
- Panes, J
- CRONICA-UC Study Investigators
Grupos
Abstract
OBJECTIVES: New e-health technologies can improve patient-physician communication and contribute to optimal patient care. We compared the diagnostic performance of the Simple Clinical Colitis Activity Index (SCCAI) self-administered by patients with ulcerative colitis (UC) at home (through a website) with the in-clinic gastroenterologist-assessed SCCAI. METHODS: Patients were followed-up over 6 months. At months 3 and 6, patients completed the SCCAI online at home; within 48 h, gastroenterologists (blinded to patients' scores) completed the in-clinic SCCAI (reference). SCCAI scores were dichotomized to remission or active disease, and SCCAI changes in disease activity from month 3 to 6 were classed as worsening, stability, or improvement. RESULTS: A total of 199 patients (median age: 38 years; 56% female) contributed with 340 pairs of questionnaires. Correlation of SCCAI scores by patients and physicians was good (Spearman's rho=0.79), with 85% agreement for remission or activity (95% CI: 80.8-88.6, kappa=0.66). The negative predictive value for active disease was 94.5% (91.4-96.6); the positive predictive value was 68.0% (58.8-69.2). Agreement between patient and physician was higher in the 168 month 6 pairs than in the 172 month 3 pairs of questionnaires (89.3% (83.6-93.1) vs. 80.8% (74.2-86.0), P=0.027). CONCLUSIONS: In patients with UC, SCCAI self-administration via an online tool resulted in a high percentage of agreement with evaluation by gastroenterologists, with a remarkably high negative predictive value for disease activity. Remote monitoring of UC patients is possible and might reduce hospital visits.
Datos de la publicación
- ISSN/ISSNe:
- 0002-9270, 1572-0241
- Tipo:
- Article
- Páginas:
- 261-268
- DOI:
- 10.1038/ajg.2015.403
- PubMed:
- 26753886
- Factor de Impacto:
- 4,280 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
AMERICAN JOURNAL OF GASTROENTEROLOGY LIPPINCOTT WILLIAMS & WILKINS
Citas Recibidas en Web of Science: 51
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Filiaciones
Campos de Estudio
Cita
Marin I,NOS P,Domenech E,Riestra S,Gisbert JP,Calvet X,Cortes X,Iglesias E,Huguet JM,Taxonera C,Fernandez R,Carpio D,Gutierrez A,Guardiola J,Laria LC,Sicilia B,Bujanda L,Cea L,Romero C,Rincon O,Julia B,Panes J,CRONICA I. INFLAMMATORY BOWEL DISEASE Diagnostic Performance of the Simple Clinical Colitis Activity Index Self-Administered Online at Home by Patients With Ulcerative Colitis: CRONICA-UC Study. Am. J. Gastroenterol. 2016. 111. (2):p. 261-268. IF:9,566. (1).