Blunted cortisol response to stress in patients with eating disorders: Its association to bulimic features

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Vaz-Leal, FJ
  • Ramos-Fuentes, MI
  • Rodriguez-Santos, L
  • Chimpen-Lopez, C
  • Fernandez-Sanchez, N
  • Zamora-Rodriguez, FJ
  • Beato-Fernandez, L
  • Guisado-Macias, JA

Grupos

Abstract

ObjectiveClinical research on cortisol response to stress in patients with eating disorders has provided controversial and even contradictory results. As this might be the consequence of the inclusion in the studies of heterogeneous clinical populations, 3 highly selected samples were studied. MethodsDexamethasone suppression test was performed on 15 restricting anorexia nervosa patients without history of bulimia nervosa (BN), 17 BN patients with normal weight and no history of anorexia nervosa, and 22 healthy controls. Three days later, the Trier Social Stress Test was applied, and 8 saliva samples were collected along the trial for cortisol assessment. ResultsWhen the patients were considered as a single group, a slightly blunted cortisol response to stress was observed, but when the 3 groups were considered separately, the blunted response was observed only in the BN patients. DiscussionThe results support the association between blunted cortisol response and bulimic features.

Datos de la publicación

ISSN/ISSNe:
1072-4133, 1099-0968

EUROPEAN EATING DISORDERS REVIEW  WILEY

Tipo:
Article
Páginas:
207-216
Factor de Impacto:
1,150 SCImago
Cuartil:
Q1 SCImago

Citas Recibidas en Web of Science: 7

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Keywords

  • cortisol; eating disorders; hypothalamus-pituitary-adrenal axis; stress; Trier Social Stress Test

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