Prognostic Tomographic Classification of Myopic Choroidal Neovascularization

Autores de IIS La Fe

• María Andreu Fenoll

  Autor

• Rosa Dolz Marco

  Autor

• Roberto Gallego Pinazo

  Autor

Participantes ajenos a IIS La Fe

• Pascual-Camps, I
• Ruiz-Moreno, JM

Grupos

• Biomedicina Molecular, Celular y Genómica

  

  Leader

  José María Millán Salvador

Abstract

BACKGROUND AND OBJECTIVES: To investigate the prognostic value of the development of a hyperr-eflective envelopment of the neovascular tissue in myopic choroidal neovascularization (mCNV) after the first intravitreal ranibizumab injection and to establish a tomographic classification of mCNV depending on this healing process. PATIENTS AND METHODS: Twenty-five eyes of 25 patients with mCNV were retrospectively studied. Patients were classified into type A (presence of a hyperreflective coating of the neovascular tissue 1 month after first intravitreal ranibizumab) and type B (absence of or partial coating). Visual acuity (VA) and number of injections were recorded. Differences between both types were assessed at 6 and 12 months of follow-up. RESULTS: Fifteen patients (60%) were classified as type A and 10 as type B (40%). Type A showed better VA than type B. VA improvement was only significant for type A. No differences in the number of injections were observed; however, a trend to a larger amount in type B was observed. CONCLUSIONS: The proposed classification may have prognostic value, with type A mCNV showing better visual outcomes. Further studies are needed to confirm these findings.

Keywords

• PATHOLOGICAL MYOPIA; MACULAR DEGENERATION; THERAPY; SECONDARY