Use of Dexmedetomidine in Cardiothoracic and Vascular Anesthesia

Data de publicació: Data Ahead of Print:

Autors de IIS La Fe

Autors aliens a IIS La Fe

  • Gallego-Ligorit, L
  • Vives, M
  • Valles-Torres, J
  • Sanjuan-Villarreal, TA
  • Iglesias, M

Grups d'Investigació

Abstract

Dexmedetomidine is a highly selective alpha(2)-adrenergic agonist with analgesic and sedative properties. In the United States, the Food and Drug Administration approved the use of the drug for short-lasting sedation (24 h) in intensive care units (ICUs) in patients undergoing mechanical ventilation and endotracheal intubation. In October 2008, the Food and Drug Administration extended use of the drug for the sedation of nonintubated patients before and during surgical and nonsurgical procedures. In the European Union, the European Medicine Agency approved the use of dexmedetomidine in September 2011 with a single recognized indication: ICU adult patients requiring mild sedation and awakening in response to verbal stimulus. At present, the use of dexmedetomidine for sedation outside the ICU remains an off-label indication. The benefits of dexmedetomidine in critically ill patients and in cardiac, electrophysiology-related, vascular, and thoracic procedures are discussed. (C) 2017 Elsevier Inc. All rights reserved.

Dades de la publicació

ISSN/ISSNe:
1053-0770, 1532-8422

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA  W B SAUNDERS CO-ELSEVIER INC

Tipus:
Review
Pàgines:
1426-1438
PubMed:
29325842
Factor d'Impacte:
0,592 SCImago
Quartil:
Q2 SCImago

Cites Rebudes en Web of Science: 15

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Keywords

  • Dexmedetomidine sedation; cardiothoracic and vascular anesthesia; delirium; cardiac catheterization laboratory and electrophysiology (EP)-related procedures sedation

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