Portal de investigación
A national survey on the efficacy and safety of continuous subcutaneous insulin infusion in patients with type 1 diabetes in Spain
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Beato-Vibora, P
- Chico-Ballesteros, A
- Gimenez, M
- Guerrero-Vazquez, R
- Barrio-Castellanos, R
- Goñi-Iriarte MJ
- Diaz-Soto, G
- Moreno-Fernandez, J
- Martinez-Brocca, MA
- Diabetes Technology Working Group of the Spanish Diabetes Association
Grupos
Abstract
Aims: To assess safety and benefits of continuous subcutaneous insulin infusion (CSII) therapy in a cohort of type 1 diabetes patients in Spain. Methods: A web-based national registry was created by the Working Group of the Spanish Diabetes Association. All patients on CSII being followed at selected referral centers were included. A cross-sectional analysis was performed. Results: A total of 1275 patients were included. Data completion for patients on CSII was 67 +/- 32%. Indications for treatment were suboptimal glycemic control (32%), high glucose variability (24%), preconception care (14%) and hypoglycemia (11%). In the patients on CSII for >= 1 year (n = 843, mean CSII duration of 5 years), HbA(1c) decreased by 5 mmol/mol (0.5%) in the whole population and by 8 mmol/mol (0.7%) in subjects with suboptimal glycemic control as CSII indication. Percentage of patients achieving HbA(1c) <= 53 mmol/mol (7%) increased from 20% before CSII to 34% at the end of follow-up. Severe hypoglycemia decreased from 29% to 5%. The rate of discontinuation was 9.5%. HbA(1c) was lower in patients using bolus advisor and temporary basal rates. Conclusions: CSII was associated with a sustained improvement in glycemic control and a reduction in severe hypoglycemia. The use of advanced CSII settings was related to better glycemic control. (C) 2017 Elsevier B.V. All rights reserved.
Datos de la publicación
- ISSN/ISSNe:
- 0168-8227, 1872-8227
- Tipo:
- Article
- Páginas:
- 56-63
- PubMed:
- 29278712
- Factor de Impacto:
- 1,206 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
DIABETES RESEARCH AND CLINICAL PRACTICE ELSEVIER IRELAND LTD
Citas Recibidas en Web of Science: 13
Documentos
- No hay documentos
Filiaciones
Keywords
- Type 1 diabetes; Continuous subcutaneous insulin infusion; HbA1c
Cita
Beato P,Chico A,Gimenez M,Guerrero R,Barrio R,Goñi MJ,Diaz G,MERINO JF,Moreno J,Martinez MA,Diabetes Technology Working Group of the Spanish Diabetes A. A national survey on the efficacy and safety of continuous subcutaneous insulin infusion in patients with type 1 diabetes in Spain. Diabetes Res. Clin. Pract. 2018. 137. p. 56-63. IF:3,239. (2).