Oncological results of the educational Rectal Cancer Project in Spain 10 years after its implementation

Autores de IIS La Fe

• Joaquin Navascues Ortega

  Autor

• Eduardo García-Granero Ximénez

  Autor

• Jose Vicente Roig Vila

  Autor

Participantes ajenos a IIS La Fe

• Codina Cazador A
• Biondo, S
• Espin Basany E
• Buxo, M

Grupos

• Cirugía digestiva y Cuidados perioperatorios

  

  Leader

  Matteo Frasson

Abstract

Introduction: The objective of this observational, prospective, multicenter and multilevel study was to evaluate the oncological outcomes (local recurrence, metastasis and overall survival) of the Rectal Cancer Project of the Spanish Association of Surgeons (AEC) 10 years after its initiation, comparing the results with Scandinavian registries. Methods: The AEC teaching project database includes 17,620 patients to date, of which 4,508 were operated on with a potentially curative resection between March 2006 and December 2010. All of them come from the first 59 hospitals included in the project, and therefore followed for at least 5 years, and are the subject of the present study. Results: The cumulative incidence of local recurrence was 7.3 (95% CI: 8.2-6.5), metastasis 21.0 (CI 95%: 22.4-19.7) and overall survival 72.3 (CI 95%: 80.3-77.6). The multilevel regression analysis with the hospital variable as a random effect, showed a significant variation among the hospitals for the cancer outcome variables: general survival, local recurrence and metastasis (delta 2 = 0.053). Conclusions: This study indicates that the results observed in the AEC' Rectal Cancer Project are inferior than those observed in the Scandinavian registries that we tried to emulate and that this is attributable to the variability of practice in some centers. (C) 2017 AEC. Published by Elsevier Espana, S.L.U. All rights reserved.

Keywords

• Rectal cancer; Local recurrence; Metastases; Overall survival