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  3. Chronic ethanol consumption enhances interleukin-1-mediated signal transduction in rat liver and in cultured hepatocytes.

Chronic ethanol consumption enhances interleukin-1-mediated signal transduction in rat liver and in cultured hepatocytes.

Data de publicació:

Autors de IIS La Fe

Autors aliens a IIS La Fe

  • Valles SL
  • Guasch R

Abstract

Interleukin-1 (IL-1) is a central mediator of the inflammatory process. Increased serum levels of IL-1 have been reported in alcoholics with liver damage, but it remains unknown whether chronic ethanol intake, in the presence or absence of lipopolysaccharide (LPS), activates IL-1 release and signaling in the hepatocyte.

Dades de la publicació

ISSN/ISSNe:
0145-6008, 1530-0277

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH  Wiley-Blackwell

Tipus:
Article
Pàgines:
1979-1986
PubMed:
14691386
Factor d'Impacte:
1,200 SCImago ℠
Quartil:
Q1 SCImago ℠

Cites Rebudes en Web of Science: 51

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  • No hi ha documents

Mètriques

Filiacions mostrar / ocultar

Keywords

  • alcoholic liver disease; NF kappa B; IL-1 beta; IRAK; ERK1/2

Projectes associats

INVESTIGACION EN RED DE LAS ENFERMEDADES NEUROLOGICAS

Investigador Principal: JUAN JESÚS VÍLCHEZ PADILLA

C03/06 . INSTITUTO DE SALUD CARLOS III . 2003

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