Portal de investigación
Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB
Fecha de publicación:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Romm, H
- Ainsbury, EA
- Barquinero, JF
- Barrios, L
- Beinke, C
- Cucu, A
- Domene, MM
- Filippi, S
- Monteiro Gil O
- Gregoire, E
- Hadjidekova, V
- Hatzi, V
- Lindholm, C
- M'kacher, R
- Moquet, J
- Noditi, M
- Oestreicher, U
- Palitti, F
- Pantelias, G
- Prieto, MJ
- Popescu, I
- Rothkamm, K
- Sommer, S
- Terzoudi, G
- Testa, A
- Wojcik, A
Grupos
Abstract
Purpose: To establish a training data set of digital images and to investigate the scoring criteria and dose assessment of the dicentric assay within the European network of biodosimetry (RENEB), a web based scoring inter-comparison was undertaken by 17 RENEB partners. Materials and methods: Two sets of 50 high resolution images were uploaded onto the RENEB web site. One set included metaphases after a moderate exposure (1.3 Gy) and the other set consisted of metaphases after a high dose exposure (3.5 Gy). The laboratories used their own calibration curves for estimating doses based on observed aberration frequencies. Results: The dose estimations and 95% confidence limits were compared to the actual doses and the corresponding z-values were satisfactory for the majority; only the dose estimations from two laboratories were too low or too high. The coefficients of variation were 17.6% for the moderate and 11.2% for the high dose. Metaphases with controversial results could be identified for training purposes. Conclusions: Overall, the web based scoring of the two galleries by the 17 laboratories produced very good results. Application of web based scoring for the dicentric assay may therefore be a relevant strategy for an operational biodosimetry assistance network.
Datos de la publicación
- ISSN/ISSNe:
- 0955-3002, 1362-3095
- Tipo:
- Article
- Páginas:
- 110-117
- Factor de Impacto:
- 0,653 SCImago ℠
- Cuartil:
- Q2 SCImago ℠
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY TAYLOR & FRANCIS LTD
Citas Recibidas en Web of Science: 13
Documentos
- No hay documentos
Filiaciones
Keywords
- Web based scoring; biological dosimetry; dicentric assay; radiation; biodosimetry network
Proyectos asociados
REALIZING THE EUROPEAN NETWORK IN BIODOSIMETRY (RENEB)
295513_RENEB_PE_MONTORO_FP7-Fission-2011 . FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA . 2012
CONTROL Y SEGUIMIENTO INTEGRAL DE LA RADIACIÓN IONIZANTE RECIBIDA TRAS EXPLORACIONES MÉDICAS: COSIRI.
Investigador Principal: ÁNGEL ALBERICH BAYARRI
GV/2015/132 . FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA; CONSELLERIA DE EDUCACION . 2015
Cita
Romm H,Ainsbury EA,Barquinero JF,Barrios L,Beinke C,Cucu A,Domene MM,Filippi S,Monteiro O,Gregoire E,Hadjidekova V,Hatzi V,Lindholm C,M'kacher R,Montoro A,Moquet J,Noditi M,Oestreicher U,Palitti F,Pantelias G,Prieto MJ,Popescu I,Rothkamm K,Sebastia N,Sommer S,Terzoudi G,Testa A,Wojcik A. Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB. Int J Radiat Biol. 2017. 93. (1):p. 110-117. IF:1,970. (1).