AML-389 Phase 1/2 Study of SEL24/MEN1703, a First-in-Class Dual PIM/FLT3 Kinase Inhibitor, in Patients With IDH1/2-Mutated Acute Myeloid Leukemia: The DIAMOND-01 Trial
Fecha de publicación:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Martinelli G.
- Santoro A.
- Gambacorti-Passerini C.
- Polo S.V.
- Solomon S.R.
- Mukherjee S.
- Lech-Maranda E.
- Levy M.Y.
- Wierzbowska A.
- Calbacho-Robles M.
- Marconi G.
- Giannini M.B.
- Angelosanto N.
- Mughal T.I.
- Galleu A.
- Blotta S.
- Ravandi F.
Grupos
Abstract
Abstract no disponible
Datos de la publicación
- ISSN/ISSNe:
- 2152-2650, 2152-2669
- Tipo:
- Article
- Páginas:
- 243-244
- Enlace a otro recurso:
- www.scopus.com
- Factor de Impacto:
- 0,778 SCImago ℠
- Cuartil:
- Q2 SCImago ℠
Clinical Lymphoma Myeloma & Leukemia CIG MEDIA GROUP, LP
Documentos
- No hay documentos
Filiaciones
Filiaciones no disponibles
Keywords
- Flt3 ligand; protein kinase Pim 1; protein tyrosine kinase; protein tyrosine kinase inhibitor; sel 24men 1703; unclassified drug; acute myeloid leukemia; adult; antineoplastic activity; Article; asthenia; blood cell count; cancer patient; cancer recurrence; cancer resistance; clinical article; cohort analysis; drug dose escalation; drug safety; gene mutation; hematopoietic stem cell; human; human cell; leukemia remission; monotherapy; multicenter study; multiple cycle treatment; open study; outcome assessment; overall response rate; phase 1 clinical trial; phase 2 clinical trial; pneumonia; preliminary data; recommended drug dose; remission; transplantation
Campos de Estudio
Cita
Martinelli G,Santoro A,Gambacorti C,Polo SV,Solomon SR,Mukherjee S,Lech E,Levy MY,Wierzbowska A,Calbacho M,Marconi G,Giannini MB,CANO I,MIÑANA LT,ACUÑA E,Angelosanto N,Mughal TI,Galleu A,Blotta S,Ravandi F,MONTESINOS P. AML-389 Phase 1/2 Study of SEL24/MEN1703, a First-in-Class Dual PIM/FLT3 Kinase Inhibitor, in Patients With IDH1/2-Mutated Acute Myeloid Leukemia: The DIAMOND-01 Trial. Clin. Lymphoma Myeloma Leukemia. 2022. 22. p. 243-244. IF:2,700. (3).
Portal de investigación