Knowledge of biological therapy for patients with immune-mediated diseases. BIOINFO Study;

Autores de IIS La Fe

• Tomás Palanques Pastor

  Autor

Participantes ajenos a IIS La Fe

• Seguí-Solanes C.
• Estrada L.
• Ramírez Herráiz E.
• Ruiz-García S.
• Merino Bohórquez V.
• Capilla Montes C.
• Borras-Blasco J.

Grupos

• Grupo de Investigación de Farmacia

Abstract

Objective: To determine the degree of knowledge about biological therapy and biosimilars in patients with immune-mediated inflammatory diseases treated in Outpatient Pharmaceutical Care Units. Methods: Observational, prospective and multicenter study during the period May 2020-March 2021. A survey (9 questions) was conducted before starting treatment in which the patients' level of knowledge about biological therapy and biosimilars was assessed. Results: A total of 169 patients were included in the study. The average value for the different questions was 3.3 ± 0.6 out of 5, while the average final result was 29.4 points out of 45. Sixty-four percent of the patients had an acceptable level before starting the medication (>27 points). The multivariate analysis showed a statistically significant correlation (p < 0.05) with a better score at the beginning of treatment in those patients whose prescribing service was Rheumatology. Conclusions: In general, the level of knowledge prior to biological therapy in patients is acceptable, being higher in dosage and administration technique related-factors and what is related to the dosage and administration technique and where to find information related to the medication; the worst rated were those on biosimilars-related. The factor of being followed by rheumatology, was associated with better knowledge. © 2024 Sociedad Española de Farmacia Hospitalaria (S.E.F.H)

Keywords

• Adult; Aged; Biological Therapy; Biosimilar Pharmaceuticals; Female; Health Knowledge, Attitudes, Practice; Humans; Immune System Diseases; Male; Middle Aged; Prospective Studies; Surveys and Questionnaires; biosimilar agent; Article; biological therapy; human; inflammatory disease; knowledge; major clinical study; multicenter study; observational study; outpatient care; prospective study; adult; aged; attitude to health; clinical trial; drug therapy; female; immunopathology; male; middle aged; questionnaire