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  3. Impact of gender on in-hospital and long-term outcomes after transcatheter aortic valve implantation: an analysis of the Spanish TAVI registry;

Impact of gender on in-hospital and long-term outcomes after transcatheter aortic valve implantation: an analysis of the Spanish TAVI registry;

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Gabani R.
  • Brugaletta S.
  • Bujak K.
  • Pèrez-Vizcayno M.J.
  • Jiménez-Quevedo P.
  • Arévalos V.
  • Muñoz-García E.
  • Trillo-Nouche R.
  • del Valle R.
  • de la Torre Hernández J.M.
  • Salido L.
  • Gutiérrez E.
  • Pan M.
  • Sánchez-Gila J.
  • García del Blanco B.
  • Moreno R.
  • Blanco Mata R.
  • Oteo J.F.
  • Amat-Santos I.
  • Regueiro A.
  • Nogales J.M.
  • Fernández-Nofrerías E.
  • Andraka L.
  • Ferrer M.C.
  • Pinar E.
  • Romaguera R.
  • Cuellas Ramón C.
  • Alfonso F.
  • García-Blas S.
  • Piñero A.
  • Ignasi J.
  • Díaz Mèndez R.
  • Bordes P.
  • Meseguer J.
  • Nombela-Franco L.
  • Sabaté M.

Grupos

Abstract

Introduction and objectives: Impact of gender on long-term outcomes after transcatheter aortic valve implantation (TAVI) remains uncertain. We aimed to investigate gender-specific differences in TAVI and its impact on outcomes. Methods: This analysis used data from the prospective Spanish TAVI registry, which included consecutive TAVI patients treated in 46 Spanish centers from 2009 to 2021. The primary endpoint was all-cause mortality at 12 months. Secondary endpoints included in-hospital and 30-day mortality and TAVI-related complications. Adjusted logistic and Cox regression analyses were performed. Results: The study included 12 253 consecutive TAVI patients with a mean age of 81.2 ± 6.4 years. Women (53.9%) were older, and had a higher STS-PROM score (7.0 ± 7.0 vs 6.2 ± 6.7; P < .001) than men. Overall, the TAVI-related complication rate was similar between women and men, with specific gender-related complications. While women more frequently developed in-hospital vascular complications (13.6% vs 9.8%; P < .001) and cardiac tamponade (1.5% vs 0.6%; P = .009), men showed a higher incidence of permanent pacemaker implantation (14.5% vs 17.4%; P = .009). There was no difference in all-cause mortality either in hospital (3.6% vs 3.6%, adjusted OR, 1.01; 95%CI, 0.83-1.23; P = .902), at 30 days (4.2% vs 4.2%, adjusted OR, 0.90; 95%CI, 0.65-1.25; P = .564) or at 1 year (11% vs 13%, adjusted HR, 0.94; 95%CI, 0.80-1.11; P = .60). Conclusions: Women treated with TAVI are older and have more comorbidities than men, leading to distinct complications between genders. Nevertheless, all-cause mortality in the short-term and at 1-year was similar between men and women. © 2024 Sociedad Española de Cardiología

Datos de la publicación

ISSN/ISSNe:
0300-8932, 1579-2242

REVISTA ESPANOLA DE CARDIOLOGIA  EDICIONES DOYMA S A

Tipo:
Article
Páginas:
338-346
PubMed:
39187234
Enlace a otro recurso:
www.scopus.com
Factor de Impacto:
0,407 SCImago ℠
Cuartil:
Q3 SCImago ℠

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Keywords

  • Aged; Aged, 80 and over; Aortic Valve Stenosis; Female; Follow-Up Studies; Hospital Mortality; Humans; Male; Postoperative Complications; Prospective Studies; Registries; Risk Factors; Sex Factors; Spain; Survival Rate; Time Factors; Transcatheter Aortic Valve Replacement; Treatment Outcome; aged; all cause mortality; Article; clinical outcome; comorbidity; controlled study; female; heart tamponade; human; major clinical study; male; mortality rate; sex difference; transcatheter aortic valve implantation; very elderly; aortic valve stenosis; clinical trial; epidemiology; follow up; hospital mortality; multicenter study; postoperative complication; procedures; prospective study; register; risk factor; sex factor; Spain; surgery; survival rate; time factor; treatment outcome

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