Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.

Autores de IIS La Fe

• Rafael Vázquez Manrique

  Autor

Participantes ajenos a IIS La Fe

• Lejeune FX
• Mesrob L
• Parmentier F
• Bicep C
• Parker JA
• Vert JP
• Tourette C
• Neri C

Abstract

A central goal in Huntington's disease (HD) research is to identify and prioritize candidate targets for neuroprotective intervention, which requires genome-scale information on the modifiers of early-stage neuron injury in HD.