Real-life experience with transvaginal radiofrequency ablation in infertile patients with types 2 and 3 fibroids

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Cerrillo, M
  • Martinez-Salazar, J
  • Fernandez, C
  • Royo, P
  • Vazquez, A
  • Munoz, E
  • Gomez, VH
  • Puente, J

Grupos

Abstract

Research question: Transvaginal radiofrequency ablation (TRFA) may offer a safe and effective alternative to surgery for infertile women with type 2 or 3 fibroids under 4 cm diameter that compromise the uterine cavity. Methods: In this study, 36 patients underwent ultrasound-guided TRFA between 2020 and 2023. Main outcomes were fibroid volume reduction at 1, 3, and 6 months, and post-procedure reproductive results. Results: Mean baseline fibroid volume was 19.29 cm(3), decreasing to 9.6 cm(3) at 1 month, 4.39 cm(3) at 3 months, and 4.07 cm(3) at 6 months, reflecting >75% reduction. Mild pain and minimal bleeding occurred in 22% of patients; hysteroscopic removal of protruding fibroids was required in 22%. Among the 25 women undergoing subsequent ART, pregnancy and miscarriage rates per treated patient were 68% and 16%, respectively; live births occurred in 52%, with most deliveries at full-term. Caesarean delivery rate was 69.2%. Conclusions: TRFA appears to be a safe and effective alternative to surgery for infertile women with type 2 or 3 fibroids under 4 cm in diameter that compromise the uterine cavity. The procedure does not seem to affect reproductive outcomes, and this study is the first to assess the effect of TRFA on ART.

Copyright © 2025 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Datos de la publicación

ISSN/ISSNe:
1472-6483, 1472-6491

REPRODUCTIVE BIOMEDICINE ONLINE  ELSEVIER SCI LTD

Tipo:
Article
Páginas:
105104-105104
PubMed:
41352224
Enlace a otro recurso:
www.scopus.com
Factor de Impacto:
1,171 SCImago
Cuartil:
Q1 SCImago

Citas Recibidas en Web of Science: 3

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Keywords

  • Ablation; Fibroids; Infertile; Radiofrequency; Transvaginal radiofrequency ablation; Ultrasound

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