Reference Ranges for Preductal Oxygen Saturation and Heart Rate in Moderate and Late Preterm Infants with Deferred Cord Clamping

Autores de IIS La Fe

• Nerea Valles Murcia

  Autor

• Álvaro José Solaz García

  Autor

• Alejandro Pinilla González

  Autor

• Laura Torrejón Rodríguez

  Autor

• María José Gormaz Moreno

  Autor

• Raquel Escrig Fernández

  Autor

• Alba González Timoneda

  Autor

• María Cernada Badía

  Autor

• Máximo Vento Torres

  Autor

Grupos

• Perinatología

• Salud Cardiovascular Materna, Preeclampsia y Parto Prematuro

Abstract

Introduction: Moderate and late preterm (MLPT) infants represent a substantial percentage of all preterm infants and frequently need support in the delivery room. Deferred cord clamping (DCC) improves SpO(2) and heart rate (HR) stabilization in term infants. However, data on MLPT infants are limited. Methods: We performed a prospective observational study collecting SpO(2) and HR by pulse oximetry in healthy MLPT infants with DDC to construct percentile graphs for the first 10 min after birth. Results: A total of 96 MLPT infants were monitored for preductal SpO(2) and HR, and percentiles were calculated. SpO(2) mean was significantly lower for MLPT than for term infants during the first 6 min after birth, and 15% did not achieve SpO(2) >= 85% in the first 5 min after birth. HR was significantly lower in MLPT infants in the first 4 min after birth; however, HR consistently remained above bradycardic values (>100 bpm). NICU admission and postnatal complications were not different between MLPT achieving SpO(2) >= 85% or not. Conclusion: MLPT infants with DCC achieved stable SpO(2) and HR significantly later, 6 min and 4 min, respectively, than term infants. In addition, 15% of MLPT infants did not achieve SpO(2) >= 85% at 5 min after birth. However, admission to the NICU and clinical evolution did not differ from newborns with SpO(2) >= 85% at 5 min. Larger studies including long-term follow-up are needed to assess if lower SpO(2) in the first 5 min has clinical consequences in non-resuscitated MLPT.

© 2024 S. Karger AG, Basel.

Keywords

• Moderate and late preterm; Oxygen saturation; Heart rate; Delivery room; Reference ranges; Delayed cord clamping