Portal de investigación
Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility.
Fecha de publicación:
Fecha Ahead of Print:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Mari A
- Calabrese F
- Pasta A
- Lorenzon G
- Weusten B
- Keller J
- Visaggi P
- Roman S
- Marabotto E
- Dickman R
- Serra J
- De Bortoli N
- Iovino P
- Pohl D
- Dumitrascu D
- Ribolsi M
- Barber C
- Bor S
- Fox M
- Sweiss R
- Akyuz F
- Ghisa M
- Celebi A
- Shibli F
- Dziewas R
- Kalkan IH
- Tack J
- Clavé P
- Carrion S
- Cheng I
- Tomsen N
- Ortega O
- Rubio SM
- Pizzorni N
- Michou E
- Regan J
- Hamdy S
- Rommel N
- Scharitzer M
- Ekberg O
- Schindler A
- Speyer R
- Gillman A
- Zerbib F
- Savarino EV
Grupos
Abstract
Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia. Despite its clinical importance, dysphagia is associated with several uncertainties regarding its optimal diagnostic work-up and management, particularly, considering the progress with diagnostic modalities and technologies. A Delphi consensus was performed with experts from various disciplines who conducted a literature summary and voting process on 41 statements. Quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation criteria. Consensus was reached for all the statements. The panel agreed with the definition and prevalence of esophageal and OD types. The role of endoscopy, high-resolution manometry, EndoFLIP, barium swallow and other imaging tests in evaluating esophageal dysphagia has reached overall strong agreement. Videofluoroscopic swallow study, alongside fiber-endoscopic evaluation of swallowing, as the methods of choice for the instrumental assessment of oropharyngeal dysfunction is a strong recommendation. Regarding treatment, a weak recommendation was achieved for the use of PPIs, calcium-channel blockers, nitrates, phosphodiesterase type 5 inhibitors, antidepressants or peppermint oil for the treatment of hypercontractile esophagus. A strong recommendation exists for endoscopic and surgical treatment of achalasia, while a weak recommendation is provided for other esophageal motility disorders. Regarding OD, a weak recommendation was achieved for swallow therapy, to improve swallowing mechanics, reduce symptoms, and enhance quality of life. Swallow therapy could be more effective when using validated assessment tools, consistent treatment parameters, and considering long-term follow-up. A multinational group of European experts summarized the current state of consensus on the definition, diagnosis, and management of dysphagia.
© 2025 The Author(s). United European Gastroenterology Journal published by Wiley Periodicals LLC on behalf of United European Gastroenterology.
Datos de la publicación
- ISSN/ISSNe:
- 2050-6406, 2050-6414
- Tipo:
- Article
- Páginas:
- 855-901
- DOI:
- 10.1002/ueg2.70062
- PubMed:
- 40543044
- Factor de Impacto:
- 1,445 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
United European Gastroenterology Journal SAGE PUBLICATIONS INC
Citas Recibidas en Web of Science: 15
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- No hay documentos
Filiaciones
Keywords
- Delphi consensus; barium swallow; diagnosis; dysphagia; esophageal motility disorders; high resolution manometry (HRM); management; oropharyngeal dysphagia; workup
Campos de Estudio
Cita
Mari A,Calabrese F,Pasta A,Lorenzon G,Weusten B,Keller J,Visaggi P,Roman S,Marabotto E,Dickman R,Serra J,De Bortoli N,Iovino P,Pohl D,Dumitrascu D,Ribolsi M,Barber C,Bor S,Fox M,Sweiss R,LORENZO V,Akyuz F,Ghisa M,Celebi A,Shibli F,Dziewas R,Kalkan IH,Tack J,Clavé P,Carrion S,Cheng I,Tomsen N,Ortega O,Rubio SM,Pizzorni N,Michou E,Regan J,Hamdy S,Rommel N,Scharitzer M,Ekberg O,Schindler A,Speyer R,Gillman A,Zerbib F,Savarino EV. Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility. United European Gastroenterol. J. 2025. 13. (6):p. 855-901. IF:6,400. (1).