Portal de investigación
Relationship between neuroimaging and emotion recognition in mild cognitive impairment patients.
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Adrián-Ventura J
Grupos
Abstract
OBJECTIVE: Dementia is a major public health problem with high needs for early detection, efficient treatment, and prognosis evaluation. Social cognition impairment could be an early dementia indicator and can be assessed with emotion recognition evaluation tests. The purpose of this study is to investigate the link between different brain imaging modalities and cognitive status in Mild Cognitive Impairment (MCI) patients, with the goal of uncovering potential physiopathological mechanisms based on social cognition performance. METHODS: The relationship between the Reading the Mind in the Eyes Test (RMET) and some clinical and biochemical variables ([18 F]FDG PET-CT and anatomical MR parameters, neuropsychological evaluation, and CSF biomarkers) was studied in 166 patients with MCI by using a correlational approach. RESULTS: The RMET correlated with neuropsychological variables, as well as with structural and functional brain parameters obtained from the MR and FDG-PET imaging evaluation. However, significant correlations between the RMET and CSF biomarkers were not found. DISCUSSION: Different neuroimaging parameters were found to be related to an emotion recognition task in MCI. This analysis identified potential minimally-invasive biomarkers providing some knowledge about the physiopathological mechanisms in MCI.
Copyright © 2024 Elsevier B.V. All rights reserved.
Datos de la publicación
- ISSN/ISSNe:
- 0166-4328, 1872-7549
- Tipo:
- Article
- Páginas:
- 114844-114844
- PubMed:
- 38176615
- Factor de Impacto:
- 0,890 SCImago ℠
- Cuartil:
- Q2 SCImago ℠
BEHAVIOURAL BRAIN RESEARCH ELSEVIER
Citas Recibidas en Web of Science: 4
Documentos
- No hay documentos
Filiaciones
Keywords
- Emotion recognition; Functional imaging; Minimally-invasive biomarkers; Structural imaging
Cita
GANDIA MT,Adrián J,CHÁFER C,ALVAREZ L,FERRER I,MARTINEZ B,TORRES I,BAQUERO M,MARTI L. Relationship between neuroimaging and emotion recognition in mild cognitive impairment patients. Behav. Brain Res. 2024. 461. p. 114844-114844. IF:2,300. (2).