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  3. Calling for Action: The Need of Large-Scale Cohorts to Uncover the Cardiovascular Risk in Non-Sleepy Obstructive Sleep Apnea.

Calling for Action: The Need of Large-Scale Cohorts to Uncover the Cardiovascular Risk in Non-Sleepy Obstructive Sleep Apnea.

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Maiolino G
  • Soranna D
  • Zambon A
  • Vettor R
  • Parati G
  • Gozal D
  • Pengo MF

Grupos

Abstract

Since randomized clinical trials currently do not support continuous positive airway pressure treatment of asymptomatic obstructive sleep apnea (OSA) we proposed the Obesity, Symptoms, and CARdiovascular assessment (OSCAR) algorithm to aid clinicians in the management of asymptomatic low-risk moderate-severe OSA, focusing on weight loss, symptoms and cardiovascular disease (CVD) risk assessment. Exploiting the data of the Sleep Heart Health Study we selected subjects with a body mass index (BMI) < 30 Kg/m(2), no history of CVD or sleepiness and compared 552 patients with moderate-severe OSA (OSCAR(-)) to 916 individuals without OSA (No-OSA). After adjusting for age, gender, and BMI, there was no significant difference in the risk of major adverse cardiovascular events (MACE) between OSCAR(-) and No-OSA (1.05; 95%CI 0.81-1.37). The study suggests that low-risk moderate-severe OSA patients may not have a greater risk of MACE compared to those without OSA and highlights the need for further research on this topic.

© 2024. The Author(s).

Datos de la publicación

ISSN/ISSNe:
1120-9879, 1179-1985

HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION  Adis International Ltd.

Tipo:
Article
Páginas:
-
PubMed:
39395909
Factor de Impacto:
0,749 SCImago ℠
Cuartil:
Q2 SCImago ℠

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Keywords

  • Continuous positive airway pressure; Heart disease; Obstructive; Risk factors; Sleep apnea

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