PROFUGO study protocol: Predictive model for the early diagnosis of anastomotic leak after esophagectomy and gastrectomy.

Autors de IIS La Fe

• Marcos Bruna Esteban

  Autor

Autors aliens a IIS La Fe

• Pérez Quintero R
• Serrano López AJ
• grupo PROFUGO

Grups d'Investigació

• Cirugía digestiva y Cuidados perioperatorios

  

  Leader

  Matteo Frasson

Abstract

In esophagogastric surgery, the appearance of an anastomotic leak is the most feared complication. Early diagnosis is important for optimal management and successful resolution. For this reason, different studies have investigated the value of the use of markers to predict possible postoperative complications. Because of this, research and the creation of predictive models that identify patients at high risk of developing complications are mandatory in order to obtain an early diagnosis. The PROFUGO study (PRedictivO Model for Early Diagnosis of anastomotic LEAK after esophagectomy and gastrectomy) is proposed as a prospective and multicenter national study that aims to develop, with the help of artificial intelligence methods, a predictive model that allows for the identification of high-risk cases. of anastomotic leakage and/or major complications by analyzing different clinical and analytical variables collected during the postoperative period of patients undergoing esophagectomy or gastrectomy.

Copyright © 2024. Published by Elsevier España, S.L.U.

Keywords

• Anastomotic leak; Artificial intelligence; Esofaguectomía; Esophagectomy; Fístula anastomótica; Gastrectomy; Gastrectomía; Inflammatory biomarkers; Inteligencia artificial; Marcadores inflamatorios; Modelo predictivo; Predictive model