Transcultural adaptation and validation of IMPACT-III and IMPACT-III-P in Spanish families: a multicenter study from SEGHNP.

Fecha de publicación: 21/05/2024 Fecha Ahead of Print: 01/05/2024

Autores de IIS La Fe

Esther Donat Aliaga

Autor

Participantes ajenos a IIS La Fe

Velasco Rodriguez-Belvis, Marta
Palomino, Laura
Pujol-Muncunill, Gemma
Martin-Masot, Rafael
Medina Benitez, Enrique
Fernandez-Lorenzo, Ana Estefania
Moreno-Alvarez, Ana
Molina Arias, Manuel
Hidalgo Montes, Inmaculada
Navas-Lopez, Victor Manuel
Martin de Carpi, Javier
Lozano Ruf, Ana
Blasco-Alonso, Javier
Barrio Torres, Josefa
Montraveta, Montserrat
Pena-Quintana, Luis
Ramos Rueda, Natalia
Rodriguez Martinez, Alejandro
Botija Arcos, Gonzalo
Alonso Vicente, Carmen
Castro Millan, Ana Maria
Fernandez Cebrian, Santiago
Sanchez Sanchez, Cesar
Loverdos, Ines
Segarra Canton, Oscar
Ruiz Castellano, Noelia
Torres-Peral, Ricardo
Crehua-Gaudiza, Elena
Millan Jimenez, Antonio
Jovani Casano, Carmen
Vicente Santamaria, Saioa
Tabares Gonzalez, Ana
Garcia-Romero, Ruth
Ros Arnal, Ignacio
Balboa Vega, Maria Jesus
Escartin Madurga, Laura
Martinon Torres, Nazareth
Crujeiras Martinez, Vanesa
Gonzalez-Vives, Leticia
Perez-Moneo, Begona
Masiques Mas, Maria Lluisa
Vegas Alvarez, Ana Maria
Grande Herrero, Luis
La Orden Izquierdo, Enrique
Chicano Marin, Francisco Jose
de Las Mercedes Busto Cuinas, Maria
Martinez de Zabarte Fernandez, Jose Miguel
Alberto Alonso, Jose Ramon
Andres Esteban, Eva Maria

Grupos

Enfermedad celíaca e Inmunopatología digestiva

Leader

Carmen Ribes Koninckx

Abstract

IMPACT-III and IMPACT-III-P are health-related quality of life (HRQoL) questionnaires for patients with pediatric inflammatory bowel disease (p-IBD) and their parents/caregivers. We aimed to perform a transcultural adaptation and validation for the Spanish context. Translation, back-translation, and evaluation of the questionnaires were performed by an expert committee and 12 p-IBD families. We recruited p-IBD patients aged 10-17 and their parents/caregivers. Utility, content, and face validity were considered. Validation was performed with Cronbach's alpha coefficient and varimax rotation. We confirmed the adequacy of the factor analysis using Kaiser-Meyer-Olkin (KMO) and Bartlett's sphericity tests. A confirmatory factor analysis was performed using the following goodness indexes: chi-square, Normed Fit Index (NFI), Root Mean Square Error of Approximation index (RMSEA), Standardized Root Mean Square Residual (SRMR), and Comparative Fit Index (CFI). The correlation coefficient between IMPACT-III and IMPACT-III-P was analyzed. We included 370 patients and 356 parents/caregivers (37 hospitals). Both questionnaires had good content and face validity and were considered user-friendly. The KMO measure (0.8998 and 0.9228, respectively) and Bartlett's sphericity test (p-value<0.001 for both) confirmed the adequacy of the factor analysis. The 4-factor model, complying with Kaiser's criterion, explained 89.19% and 88.87% of the variance. Cronbach's alpha (0.9123 and 0.9383) indicated excellent internal consistency. The CFA showed an adequate fit (NFI 0.941 and 0.918, RMSEA 0.048 and 0.053, SRMR 0.037 and 0.044, and CFI 0.879 and 0.913). The correlation coefficient was excellent (0.92). CONCLUSION: The SEGHNP versions of IMPACT-III and IMPACT-III-P are valid and reliable instruments for Spanish p-IBD families. WHAT IS KNOWN: IMPACT-III and parent-proxy IMPACT-III (IMPACT-III-P) are useful questionnaires for assessing health-related quality of life (HRQoL) in pediatric inflammatory bowel disease (p-IBD) patients and their parents/caregivers and have been translated and validated in several countries. To date, no transcultural adaptation and validation of these questionnaires have been published for Spanish patients with p-IBD and their families. WHAT IS NEW: This is the first transcultural adaptation and validation of IMPACT-III and IMPACT-III-P for Spanish p-IBD families. These are valid and reliable instruments for assessing HRQoL in Spanish families of patients with p-IBD.