Sellado con taurolidina en el fracaso intestinal pediátrico. Guía práctica de la Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica (SEGHNP).

Fecha de publicación: 01/05/2024 Fecha Ahead of Print: 26/04/2024

Autores de IIS La Fe

• Begoña Polo Miquel

  Autor

Participantes ajenos a IIS La Fe

• Núñez-Ramos R
• Germán Díaz M
• Moreno Villares JM
• Salazar Quero JC
• Cabello Ruiz V
• Redecillas Ferreiro S
• Ramos Boluda E

Grupos

• Enfermedad celíaca e Inmunopatología digestiva

  

  Leader

  Carmen Ribes Koninckx

Abstract

OBJECTIVES: the prevention of central line-associated bloodstream infections is a critical aspect of care for patients with intestinal failure who are treated with parenteral nutrition. The use of taurolidine in this context is becoming increasingly popular, however there is a lack of standardization in its pediatric application. The objective of this work is to develop a guide to support its prescription. METHODOLOGY: the guide is based on a review of the literature and expert opinions from the Intestinal Failure Group of the SEGHNP. It was developed through a survey distributed to all its members, addressing aspects of usual practice with this lock solution. RESULTS: this manuscript presents general recommendations concerning taurolidine indications, commercial presentations, appropriate forms of administration, use in special situations, adverse reactions, and contraindications in the pediatric population Conclusions: taurolidine is emerging as the primary lock solution used to prevent central line-associated bloodstream infections, proving to be safe and effective. This guide aims to optimize and standardize its use in pediatrics.

Keywords

• Intestinal failure; Home parenteral nutrition; Central line-associated bloodstream infection; Lock therapy; Taurolidine