Pneumonic and nonpneumonic exacerbations of COPD: inflammatory response and clinical characteristics.

Autores de IIS La Fe

• Araceli Huerta Marco

  Autor

• Rosario Menéndez Villanueva

  Autor

• Raquel Martínez Tomás

  Autor

• Juan Francisco Guerrero Martinez

  Autor

• Beatriz Montull Veiga

  Autor

• Antonio Torres Marti

  Autor

Participantes ajenos a IIS La Fe

• Crisafulli E
• Soler N

Grupos

• Infecciones Respiratorias

Abstract

Community-acquired pneumonia (CAP) is a frequent event in patients with COPD, although it is not currently considered an acute exacerbation of COPD (AECOPD). To our knowledge, no studies have compared the inflammatory response of patients with COPD who develop CAP or AECOPD. The aim of our study was to compare clinical and evolutive manifestations and biologic signaling of AECOPD and CAP + COPD.

Keywords

• OBSTRUCTIVE PULMONARY-DISEASE; COMMUNITY-ACQUIRED PNEUMONIA; ACTIVATION; PROCALCITONIN; MACROPHAGES; PREVALENCE; BIOMARKERS; PATTERNS; THERAPY; ASTHMA