Vitamins and Radioprotective Effect: A Review

Autores de IIS La Fe

• Alegría Montoro Pastor

  Autor

• Javier Flor San Onofre

  Autor

• José Miguel Soriano Del Castillo

  Autor

Participantes ajenos a IIS La Fe

• Lledo, Ines
• Ibanez, Blanca
• Melero, Ana
• Merino-Torres, Juan F.

Grupos

• Investigacion Biomédica en Imagen (GIBI 2-30)

  Investigador Principal

  Leonor Cerdá Alberich

• Unidad Mixta de Investigación en Endocrinología, Nutrición y Dietética clínica

  Leader

  Juan Francisco Merino Torres

Abstract

The radioprotective effect ex vivo, in vitro and in vivo of vitamins was reviewed using PubMed and Embase and conducted according to the PRISMA statement. A total of 38 articles were included in this review, which includes the radioprotective effect of vitamins from ex vivo, in vitro and in vivo studies. Vitamins A, C, D and E were used alone, in combination or with other nutritional and non-nutritional compounds. The use of vitamins in natural form or supplementation can be useful to reduce the radiation effect in the body, organs and/or cells. Only four (A, C, D and E) out of thirteen vitamins have been detected with radioprotective properties being mainly vitamin E followed by vitamin C, A and D.

Keywords

• radioprotection; vitamins; antioxidants; radiation