Portal de investigación
The coronavirus disease pandemic among adult congenital heart disease patients and the lessons learnt - results of a prospective multicenter european registry.
Fecha de publicación:
Fecha Ahead of Print:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Ruperti-Repilado, Francisco Javier
- Baumgartner, Helmut
- Bouma, Berto
- Bouchardy, Judith
- Budts, Werner
- Campens, Laurence
- Chessa, Massimo
- Jesus Del Cerro Marin, Maria
- Gabriel, Harald
- Gallego, Pastora
- Gonzalez, Elvira Ana
- Jensen, Annette Schophuus
- Ladouceur, Magalie
- Lockhart, Christopher
- Miranda-Barrio, Berta
- Morissens, Marielle
- Escobar, Eduardo Moreno
- Pasquet, Agnes
- Elise van den Bosch, Annemien
- Berdina van der Zwaan, Heleen
- Tobler, Daniel
- Greutmann, Matthias
- Schwerzmann, Markus
Grupos
Abstract
BACKGROUND: At the beginning of the COVID-19 pandemic, professionals in charge of particularly vulnerable populations, such as adult congenital heart disease (ACHD) patients, were confronted with difficult decision-making. We aimed to assess changes in risk stratification and outcomes of ACHD patients suffering from COVID-19 between March 2020 and April 2021. METHODS AND RESULTS: Risk stratification among ACHD experts (before and after the first outcome data were available) was assessed by means of questionnaires. In addition, COVID-19 cases and the corresponding patient characteristics were recorded among participating centres. Predictors for the outcome of interest (complicated disease course) were assessed by means of multivariable logistic regression models calculated with cluster-robust standard errors. When assessing the importance of general and ACHD specific risk factors for a complicated disease course, their overall importance and the corresponding risk perception among ACHD experts decreased over time. Overall, 638 patients (n = 168 during the first wave and n = 470 during the subsequent waves) were included (median age 34 years, 52% women). Main independent predictors for a complicated disease course were male sex, increasing age, a BMI >25 kg/m2, having =2 comorbidities, suffering from a cyanotic heart disease or having suffered COVID-19 in the first wave vs. subsequent waves. CONCLUSIONS: Apart from cyanotic heart disease, general risk factors for poor outcome in case of COVID-19 reported in the general population are equally important among ACHD patients. Risk perception among ACHD experts decreased during the course of the pandemic.
© 2022 The Authors.
Datos de la publicación
- ISSN/ISSNe:
- 2666-6685, 2666-6685
- Tipo:
- Article
- Páginas:
- 100428-100428
- PubMed:
- 36440468
- Enlace a otro recurso:
- www.scopus.com
International Journal of Cardiology Congenital Heart Disease ELSEVIER
Citas Recibidas en Web of Science: 1
Citas Recibidas en Scopus: 1
Documentos
- No hay documentos
Filiaciones
Keywords
- Adult congenital heart disease; Coronavirus disease 2019; Outcomes; Risk stratification
Cita
Ruperti FJ,Baumgartner H,Bouma B,Bouchardy J,Budts W,Campens L,Chessa M,Jesus Del Cerro Marin M,Gabriel H,Gallego P,Gonzalez EA,Jensen AS,Ladouceur M,Lockhart C,Miranda B,Morissens M,Escobar EM,Pasquet A,SORIANO JR,Elise van den Bosch A,Berdina van der Zwaan H,Tobler D,Greutmann M,Schwerzmann M. The coronavirus disease pandemic among adult congenital heart disease patients and the lessons learnt - results of a prospective multicenter european registry. Int. J. Cardiol. Congenit. Heart Dis. 2023. 11. p. 100428-100428. IF:0,800. (4).