Preventing Postendoscopic Mucosal Resection Bleeding of Large Nonpedunculated Colorectal Lesions

Data de publicació: 01/07/2022 Data Ahead of Print: 04/05/2022

Autors de IIS La Fe

Vicente María Lorenzo-Zúñiga García

Autor

Autors aliens a IIS La Fe

Albeniz, Eduardo
Montori, Sheyla
Rodriguez de Santiago, Enrique
Alvarez, Marco Antonio
Estremera-Arevalo, Fermin
Pohl, Heiko

Grups d'Investigació

Endoscopia Digestiva y Hepática

Leader

Vicente Pons Beltrán

Abstract

The most common major adverse event of endoscopic mucosal resection (EMR) is clinically significant post-EMR bleeding (CSPEB), with an incidence of 6%-7% in large lesions. Repeat colonoscopy, blood transfusions, or other interventions are often needed. The associated direct costs are much higher than those of an uncomplicated EMR. In this review, we discuss the aspects related to CSPEB of large nonpedunculated polyps, such as risk factors, predictive models, and prophylactic measures, and we highlight evidence for preventive treatment options and explore new methods for bleeding prophylaxis. We also provide recommendations for steps that can be taken before, during, and after EMR to minimize bleeding risk. Finally, this review proposes future directions to reduce CSPEB incidence.

Dades de la publicació

ISSN/ISSNe:: 0002-9270, 1572-0241
Tipus:: Article
Pàgines:: 1080-1088
DOI:: 10.14309/ajg.0000000000001819
PubMed:: 35765907
Factor d'Impacte:: 2,683 SCImago ℠
Quartil:: Q1 SCImago ℠

Documents

No hi ha documents

Mètriques

Filiacions

Albeniz, Eduardo:: Univ Publ Navarra UPNA, Endoscopy Unit, Dept Gastroenterol, Hosp Univ Navarra HUN Navarrabiomed,IdiSNA, Pamplona, Spain
Montori, Sheyla:: Univ Publ Navarra UPNA, Gastrointestinal Endoscopy Res Unit, Navarrabiomed, Hosp Univ Navarra HUN,IdiSNA, Pamplona, Spain
Rodriguez de Santiago, Enrique:: Univ Alcala, Dept Gastroenterol & Hepatol, Hosp Univ Ramon y Cajal, IRYCIS, Madrid, Spain
Lorenzo-Zuniga, Vicente:: Instituto de Investigación. Univ & Polytech Hosp La Fe IIS La Fe, Endoscopy Unit, Valencia, Spain
Alvarez, Marco Antonio:: Althaia Xarxa Assistencial Univ Manresa, Digest Dis Dept, Manresa, Spain

Inst Hosp Mar Invest Med IMIM, Barcelona, Spain
Estremera-Arevalo, Fermin:: Univ Publ Navarra UPNA, Endoscopy Unit, Dept Gastroenterol, Hosp Univ Navarra HUN Navarrabiomed,IdiSNA, Pamplona, Spain
Pohl, Heiko:: Dartmouth Geisel Sch Med, Hanover, NH 03755 USA

Dartmouth Inst, Hanover, NH USA

Vet Adm Med Ctr, Dept Gastroenterol, White River Jct, VT USA

Dartmouth Hitchcock Med Ctr, Dept Gastroenterol, Lebanon, NH 03766 USA

Keywords

DIRECT ORAL ANTICOAGULANTS; PROPHYLACTIC CLIP CLOSURE; ENDOSCOPIC RESECTION; LARGE SESSILE; GASTROINTESTINAL ENDOSCOPY; SUBMUCOSAL INJECTION; ADVERSE EVENTS; RISK-FACTORS; COLONOSCOPIC POLYPECTOMY; ANTITHROMBOTIC AGENTS

Campos d'Estudi

Projectes associats

Diseño y evaluación funcional de un nuevo dispositivo médico de catéter con balón para el tratamiento endoscópico de las fístulas del tracto digestivo. EndoFis.

Investigador Principal: MARÍA GARCÍA CAMPOS

2021/VSC/PEA/0195 . FUNDACION DE LA SOCIEDAD ESPAÑOLA DE ENDOSCOPIA DIGESTIVA . 2021

Desarrollo de endofis, un nuevo producto sanitario para el tratamiento endoscópico de las fístulas posquirúrgicas del tracto digestivo.

Investigador Principal: VICENTE MARÍA LORENZO-ZÚÑIGA GARCÍA

PI21/00193 . INSTITUTO DE SALUD CARLOS III . 2022

ENSAYO CLÍNICO DOBLE CIEGO, CONTROLADO CON PLACEBO, SOBRE LA EFICACIA DE LA ABLACIÓN ANTIRREFLUJO DE LA MUCOSA DEL CARDIAS PARA EL TRATAMIENTO DE LA ENFERMEDAD POR REFLUJO GASTROESOFÁGICO.