Portal de investigación
Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis.
Fecha de publicación:
Fecha Ahead of Print:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Prieto-Castaneda, Alejandro
- Garcia-Garrido, Fernando
- Diaz-Norambuena, Carolina
- Banuelos, Jorge
- Rebollar, Esther
- Garcia-Moreno, Inmaculada
- de la Moya, Santiago
- Agarrabeitia, Antonia R. .
- Ortiz, Maria J.
Grupos
Abstract
We have established an easy synthetic protocol for selectively developing all-orthogonal BODIPY trimers with unprecedented geometries on the basis of selecting methyl oxidation versus electrophilic formylation of key dimeric precursors. Photophysical characterization together with biological assays unraveled the most suitable BODIPY-BODIPY geometrical arrangements within the trimer, forcing them to serve as molecular platforms for the development of new, advanced heavy-atom-free photosensitizers for photodynamic therapy and phototheragnosis.
Datos de la publicación
- ISSN/ISSNe:
- 1523-7060, 1523-7052
- Tipo:
- Article
- Páginas:
- 3636-3641
- PubMed:
- 35575720
- Factor de Impacto:
- 1,669 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
ORGANIC LETTERS AMER CHEMICAL SOC
Citas Recibidas en Web of Science: 32
Documentos
- No hay documentos
Filiaciones
Keywords
- RATIONAL DESIGN; PHOTOSENSITIZERS; DIMERS
Cita
Prieto A,Garcia F,Diaz C,ESCRICHE B,GARCIA A,Banuelos J,Rebollar E,Garcia I,MARTINEZ R,de la Moya S,Agarrabeitia AR,Ortiz MJ. Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis. Org. Lett. 2022. 24. (20):p. 3636-3641. IF:5,200. (1).