Does smoking influence Crohn's disease in the biologic era? The TABACROHN study.

Autores de IIS La Fe

• Jose María Gallego Sánchez

  Autor

• Guillermo Bastida Paz

  Autor

• Silvia García Palomares

  Autor

• Carles Agusti Garcia-Navarro

  Autor

Participantes ajenos a IIS La Fe

• Nunes T
• Etchevers MJ
• Merino O
• García-Sánchez V
• Marín-Jiménez I
• Menchén L
• Barreiro-de Acosta M
• Gento E
• Ginard D
• Gomollón F
• Arroyo M
• Monfort D
• García-Planella E
• Gonzalez B
• Loras C
• Figueroa C
• Sans M
• TABACROHN Study Group of GETECCU, Spanish Working Group in Crohn's Disease and U

Grupos

• Enfermedad Inflamatoria Intestinal

Abstract

While most studies have found a negative effect of smoking on Crohn's disease (CD) phenotype, more recent data have failed to reproduce this association, which might be due to a current wider use of thiopurines and biologic therapy. The TABACROHN study aimed at defining the impact of smoking on CD in the largest published series.

Keywords

• inflammatory bowel disease; Crohn's disease; environmental factors; smoking; tobacco; disease phenotype