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  3. Angiography-derived versus invasively-determined index of microcirculatory resistance in the assessment of coronary microcirculation: A systematic review and meta-analysis.

Angiography-derived versus invasively-determined index of microcirculatory resistance in the assessment of coronary microcirculation: A systematic review and meta-analysis.

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Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Fernández-Peregrina E
  • Garcia-Garcia HM
  • Sans-Rosello J
  • Kotronias R
  • Scarsini R
  • Echavarria-Pinto M
  • Tebaldi M
  • De Maria GL

Grupos

Abstract

BACKGROUND: The index of microvascular resistance (IMR) is an established tool to assess the status of coronary microcirculation. However, the need for a pressure wire and hyperemic agents have limited its routine use and have led to the development of angiography-derived pressure-wire-free methods (angiography-derived IMR [IMRAngio]). In this review and meta-analysis, we aim to assess the global diagnosis accuracy of IMRAngio versus IMR. METHODS: A systematic review of the literature was performed. Studies directly evaluating IMRAngio versus IMR were considered eligible. Pooled values of diagnostic test and summary receiver operator curve were calculated. RESULTS: Seven studies directly comparing IMRAngio versus IMR were included (687 patients; 807 vessels). Pooled sensitivity, specificity, +likelihood ratio (LR), and -LR were 82%, 83%, 4.5, and 0.26 respectively. Pooled accuracy was 83% while pooled positive predictive value and negative predictive value were 76% and 85%, respectively. Comparable results were obtained when analyzing by clinical scenario (acute and nonacute coronary syndromes). CONCLUSION: IMRAngio shows a good diagnostic performance for the prediction of abnormal IMR.

© 2022 Wiley Periodicals LLC.

Datos de la publicación

ISSN/ISSNe:
1522-1946, 1522-726X

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS  John Wiley & Sons Inc.

Tipo:
Article
Páginas:
2018-2025
Factor de Impacto:
1,088 SCImago ℠
Cuartil:
Q1 SCImago ℠

Citas Recibidas en Web of Science: 13

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Keywords

  • angiography; coronary; microcirculation

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