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  3. Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study.

Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study.

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Papaneophytou, Christos
  • Calvis, Carme
  • Costa, Marta
  • Christodoulides, Andreas E.
  • Kroushovski, Alexander
  • Lapithis, Alkis
  • Lapithi, Vaia Maligianni
  • Papayiannis, Ioannis
  • Christou, Andreas
  • Messeguer, Ramon
  • Giannaki, Christoforos
  • Felekkis, Kyriacos

Grupos

Abstract

Specific serum biomarkers of cartilage metabolism such as cartilage oligomeric matrix protein (sCOMP) and procollagen type II C-terminal propeptide (sPIICP) as well as hyaluronan (sHA), a biomarker of synovitis, have been implicated in the pathophysiology of knee osteoarthritis (OA). However, the associations of these biomarkers with the severity of the disease and OA risk factors, including age and obesity remain inconclusive. This analysis examines the associations between these serum biomarkers and the radiographic severity of OA and knee pain, as wells as obesity, the age and gender of the participants, and other OA risk factors.

© 2022. The Author(s).

Datos de la publicación

ISSN/ISSNe:
1471-2474, 1471-2474

BMC MUSCULOSKELETAL DISORDERS  BMC

Tipo:
Article
Páginas:
195-195
PubMed:
35236298
Enlace a otro recurso:
www.scopus.com
Factor de Impacto:
0,669 SCImago ℠
Cuartil:
Q2 SCImago ℠

Citas Recibidas en Web of Science: 18

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Keywords

  • Biomarkers, COMP, HA, Knee osteoarthritis, OA risk factors, obesity, PIICP

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