In memoriam of Ricardo Flores: The career, achievements, and legacy of an inspirational plant virologist.

Data de publicació: 15/04/2022 Data Ahead of Print: 19/02/2022

Autors de IIS La Fe

María Eugenia Gas López

Autor

Autors aliens a IIS La Fe

Pallas, Vicente
Hernandez, Carmen
Marcos, Jose F.
Daròs JA
Ambros, Silvia
Navarro, Beatriz
Navarro, Jose A.
Peña M
Gago-Zachert, Selma
Carbonell, Alberto
Lopez, Carmelo
de Alba AEM
Serio FD
Moreno, Pedro

Grups d'Investigació

Unidad Mixta de Investigacion en TICs aplicadas a la reingeniería en procesos sociosanitarios (ERPSS)

Investigador Principal

María Eugenia Gas López

Abstract

Ricardo Flores (1947-2020) focused his research on the identification, replication, pathogenesis, and evolution of viroids, the minimal non-protein-coding circular RNAs (250-400 nt) able to replicate and incite diseases in plants that are remarkable for being at the lowest step of the biological scale. He and his collaborators initially identified and characterized additional group members, adding six new ones to the family Pospiviroidae, and expanding the Avsunviroidae from one to four members. They showed that members of the second family "encode" ribozymes, a property that, together with others, makes them candidates for being the most primitive replicons that emerged on our planet 3500 million years ago. He also made important contributions regarding how viroids replicate, providing relevant data on the templates, enzymes, and ribozymes that mediate this process and on the mutation rate, which turned out to be the highest reported for any biological entity. More recently, he concentrated on the role that RNA silencing could play on viroid-host interactions, describing details of this process. Ricardo also worked on citrus tristeza virus, a widely different type of subcellular pathogen, and made important contributions on the structure, localization and functions of its unique p23 protein. His research has produced 170 original articles and reviews, according to Web of Science. He encouraged the scientific careers of a large number of researchers, and collaborated with many others, some of whom have recapitulated his scientific legacy in this review and contributed with other chapters in this special issue.

Dades de la publicació

ISSN/ISSNe:: 0168-1702, 1872-7492
Tipus:: Article
Pàgines:: 198718-198718
DOI:: 10.1016/j.virusres.2022.198718
PubMed:: 35192887
Factor d'Impacte:: 1,154 SCImago ℠
Quartil:: Q1 SCImago ℠

Documents

No hi ha documents

Mètriques

Filiacions

Pallas, Vicente:: Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46011, Spain

Univ Politecn Valencia, CSIC, Inst Biol Mol & Celular Plantas, Avda Ingeniero Fausto Elio S-N, Valencia 46011, Spain
Hernandez, Carmen:: Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46011, Spain

Univ Politecn Valencia, CSIC, Inst Biol Mol & Celular Plantas, Avda Ingeniero Fausto Elio S-N, Valencia 46011, Spain
Marcos, Jose F.:: Instituto de Agroquímica y Tecnología de Alimentos (IATA), Consejo Superior de Investigaciones Científicas, Calle Catedrático Agustín Escardino 7, Paterna 46980, Spain

CSIC, Inst Agroquim & Tecnol Alimentos IATA, Calle Catedrat Agustin Escardino 7, Paterna 46980, Spain
Daròs JA:: Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46011, Spain
Ambros, Silvia:: Instituto de Biología Integrativa de Sistemas I2SysBio, Consejo Superior de Investigaciones Científicas-Universitat de Valencia, C/Catedrático Agustín Escardino 9, Parque Científico, Paterna 46980, Valencia, Spain

Univ Valencia, CSIC, Inst Biol Integrat Sistemas I2SysBio, C Catedratico Agustin Escardino 9,Parque Cient, Valencia 46980, Spain
Navarro, Beatriz:: Istituto per la Protezione Sostenibile delle Piante, Consiglio Nazionale delle Ricerche, Via Amendola 122/D, Bari 70126, Italy

CNR, Ist Protez Sostenibile Piante, Via Amendola 122-D, I-70126 Bari, Italy
Navarro, Jose A.:: Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46011, Spain

Univ Politecn Valencia, CSIC, Inst Biol Mol & Celular Plantas, Avda Ingeniero Fausto Elio S-N, Valencia 46011, Spain
Peña M:: Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46011, Spain
Gago-Zachert, Selma:: Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle/Saale D-06120, Germany

Martin Luther Univ Halle Wittenberg, Inst Biochem & Biotechnol, D-06120 Halle, Germany
Gas, Maria E.:: Instituto de Investigación. Instituto de Investigación Sanitaria La Fe de Valencia, Avda. Fernando Abril Martorell nº 106, 106 Torre H 1ª planta, Valencia 46026, Spain

Instituto de Investigación. Inst Invest Sanit La Fe Valencia, Avda Fernando Abril Martorell 106, Valencia 46026, Spain
Carbonell, Alberto:: Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46011, Spain

Univ Politecn Valencia, CSIC, Inst Biol Mol & Celular Plantas, Avda Ingeniero Fausto Elio S-N, Valencia 46011, Spain
Lopez, Carmelo:: Instituto de Conservación y Mejora de la Agrodiversidad Valenciana-Universitat Politècnica de Valencia, Avda, Ingeniero Fausto Elio s/n, Valencia 46022, Spain

Univ Politecn Valencia, Inst Conservac & Mejora Agrodiversidad Valenciana, Avda Ingeniero Fausto Elio S-N, Valencia 46022, Spain
de Alba AEM:: Department of Microbiology and Genetics, Institute for Agribiotechnology Research (CIALE), University of Salamanca, Villamayor 37185, Salamanca, Spain
Serio FD:: Istituto per la Protezione Sostenibile delle Piante, Consiglio Nazionale delle Ricerche, Via Amendola 122/D, Bari 70126, Italy
Moreno, Pedro:: Instituto Valenciano de Investigaciones Agrarias, Moncada 46113 Valencia, Spain

Inst Valenciano Invest Agr, Valencia 46113, Spain