Post-Vasectomy Semen Analysis: Optimizing Laboratory Procedures and Test Interpretation through a Clinical Audit and Global Survey of Practices.

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Agarwal, Ashok
  • Gupta, Sajal
  • Sharma, Rakesh K.
  • Finelli, Renata
  • Kuroda, Shinnosuke
  • Vij, Sarah C.
  • Boitrelle, Florence
  • Kavoussi, Parviz
  • Rambhatla, Amarnath
  • Saleh, Ramadan
  • Chung, Eric
  • Mostafa, Taymour
  • Zini, Armand
  • Ko, Edmund
  • Parekh, Neel
  • Martinez, Marlon
  • Arafa, Mohamed
  • Tadros, Nicholas
  • de la Rosette, Jean
  • Le, V, Tan
  • Rajmil, Osvaldo
  • Kandil, Hussein
  • Blecher, Gideon
  • Liguori, Giovanni
  • Caroppo, Ettore
  • Ho CCK
  • Altman, Andrew
  • Bajic, Petar
  • Goldfarb, David
  • Gill, Bradley
  • Zylbersztejn, Daniel Suslik
  • Molina JMC
  • Gava, Marcello M.
  • Cardoso JPG
  • Kosgi, Raghavender
  • Çeker G
  • Zilaitiene, Birute
  • Pescatori, Edoardo
  • Borges, Edson
  • Duarsa GWK
  • Pinggera, Germar-Michael
  • Busetto, Gian Maria
  • Balercia, Giancarlo
  • Franco, Giorgio
  • Çalik G
  • Sallam, Hassan N.
  • Park, Hyun Jun
  • Ramsay, Jonathan
  • Alvarez, Juan
  • Khalafalla, Kareim
  • Bowa, Kasonde
  • Hakim, Lukman
  • Simopoulou, Mara
  • Rodriguez, Marcelo Gabriel
  • Sabbaghian, Marjan
  • Elbardisi, Haitham
  • Timpano, Massimiliano
  • Altan, Mesut
  • Elkhouly, Mohamed
  • Al-Marhoon, Mohamed S.
  • Sadighi Gilani MA
  • Soebadi, Mohammad Ayodhia
  • Nasr-Esfahani, Mohammad Hossein
  • Vogiatzi, Paraskevi
  • Birowo, Ponco
  • Patel, Premal
  • Javed, Qaisar
  • Ambar, Rafael F.
  • Adriansjah, Ricky
  • AlSaid, Sami
  • Micic, Sava
  • Lewis, Sheena E.
  • Mutambirwa, Shingai
  • Fukuhara, Shinichiro
  • Parekattil, Sijo
  • Ahn, Sun Tae
  • Jindal, Sunil
  • Takeshima, Teppei
  • Puigvert, Ana
  • Amano, Toshiyasu
  • Barrett, Trenton
  • Toprak, Tuncay
  • Malhotra, Vineet
  • Atmoko, Widi
  • Yumura, Yasushi
  • Morimoto, Yoshiharu
  • Lima TFN
  • Kunz, Yannic
  • Kato, Yuki
  • Umemoto, Yukihiro
  • Colpi, Giovanni M.
  • Durairajanayagam, Damayanthi
  • Shah, Rupin

Grupos

Abstract

PURPOSE: The success of vasectomy is determined by the outcome of a post-vasectomy semen analysis (PVSA). This article describes a step-by-step procedure to perform PVSA accurately, report data from patients who underwent post vasectomy semen analysis between 2015 and 2021 experience, along with results from an international online survey on clinical practice. MATERIALS AND METHODS: We present a detailed step-by-step protocol for performing and interpretating PVSA testing, along with recommendations for proficiency testing, competency assessment for performing PVSA, and clinical and laboratory scenarios. Moreover, we conducted an analysis of 1,114 PVSA performed at the Cleveland Clinic's Andrology Laboratory and an online survey to understand clinician responses to the PVSA results in various countries. RESULTS: Results from our clinical experience showed that 92.1% of patients passed PVSA, with 7.9% being further tested. A total of 78 experts from 19 countries participated in the survey, and the majority reported to use time from vasectomy rather than the number of ejaculations as criterion to request PVSA. A high percentage of responders reported permitting unprotected intercourse only if PVSA samples show azoospermia while, in the presence of few non-motile sperm, the majority of responders suggested using alternative contraception, followed by another PVSA. In the presence of motile sperm, the majority of participants asked for further PVSA testing. Repeat vasectomy was mainly recommended if motile sperm were observed after multiple PVSA's. A large percentage reported to recommend a second PVSA due to the possibility of legal actions. CONCLUSIONS: Our results highlighted varying clinical practices around the globe, with controversy over the significance of non-motile sperm in the PVSA sample. Our data suggest that less stringent AUA guidelines would help improve test compliance. A large longitudinal multi-center study would clarify various doubts related to timing and interpretation of PVSA and would also help us to understand, and perhaps predict, recanalization and the potential for future failure of a vasectomy.

Copyright © 2022 Korean Society for Sexual Medicine and Andrology.

Datos de la publicación

ISSN/ISSNe:
2287-4208, 2287-4690

WORLD JOURNAL OF MENS HEALTH  KOREAN SOC SEXUAL MEDICINE & ANDROLOGY

Tipo:
Article
Páginas:
425-441
PubMed:
35021311
Factor de Impacto:
0,788 SCImago
Cuartil:
Q1 SCImago

Citas Recibidas en Web of Science: 2

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Keywords

  • Male contraception; Semen; Sperm; Survey; Vasectomy

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