ROSE: radiology, obstruction, symptoms and exposure - a Delphi consensus definition of the association of COPD and bronchiectasis by the EMBARC Airways Working Group.

Fecha de publicación: 22/11/2021 Fecha Ahead of Print: 22/11/2021

Autores de IIS La Fe

Miguel Ángel Martínez García

Autor

Participantes ajenos a IIS La Fe

Traversi L
Miravitlles M
Shteinberg M
Bossios A
Dimakou K
Jacob J
Hurst JR
Paggiaro PL
Ferri S
Hillas G
Vogel-Claussen J
Dettmer S
Aliberti S
Chalmers JD
Polverino E

Grupos

Neumología

Leader

Miguel Ángel Martínez García

Abstract

INTRODUCTION: The coexistence of COPD and bronchiectasis seems to be common and associated with a worse prognosis than for either disease individually. However, no definition of this association exists to guide researchers and clinicians. METHODS: We conducted a Delphi survey involving expert pulmonologists and radiologists from Europe, Turkey and Israel in order to define the "COPD- [bronchiectasis] BE association".A panel of 16 experts from EMBARC selected 35 statements for the survey after reviewing scientific literature. Invited participants, selected on the basis of expertise, geographical and sex distribution, were asked to express agreement on the statements. Consensus was defined as a score of =6 points (scale 0 to 9) in =70% of answers across two scoring rounds. RESULTS: 102 (72.3%) out of 141 invited experts participated in the first round. Their response rate in the second round was 81%. The final consensus definition of "COPD-BE association" was: "The coexistence of (1) specific radiological findings (abnormal bronchial dilatation, airways visible within 1 cm of pleura and/or lack of tapering sign in =1 pulmonary segment and in >1 lobe) with (2) an obstructive pattern on spirometry ([forced expiratory volume in 1 s] FEV(1)/[forced vital capacity] FVC <0.7), (3) at least two characteristic symptoms (cough, expectoration, dyspnoea, fatigue, frequent infections) and (4) current or past exposure to smoke (=10 pack-years) or other toxic agents (biomass, etc.)". These criteria form the acronym "ROSE" (Radiology, Obstruction, Symptoms, Exposure). CONCLUSIONS: The Delphi process formulated a European consensus definition of "COPD-BE association". We hope this definition will have broad applicability across clinical practice and research in the future.

Datos de la publicación

ISSN/ISSNe:: 2312-0541, 2312-0541
Tipo:: Article
Páginas:: -
DOI:: 10.1183/23120541.00399-2021
PubMed:: 34820447
Factor de Impacto:: 0,944 SCImago ℠
Cuartil:: Q2 SCImago ℠

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Métricas

Filiaciones

Traversi L:: Dept of Medicine and Surgery, Respiratory Diseases, Università dell'Insubria, Varese-Como, Italy

Pneumology Dept, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona, Spain
Miravitlles M:: Pneumology Dept, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona, Spain

CIBER de Enfermedades Respiratorias, Barcelona, Spain
Martinez-Garcia MA:: CIBER de Enfermedades Respiratorias, Barcelona, Spain

Respiratory Dept, La Fe University and Polytechnic Hospital, Valencia, Spain
Shteinberg M:: Pulmonology Institute and Cystic Fibrosis Center, Carmel Medical Center, and the Technion - Israel Institute of Technology, the B. Rappaport Faculty of Medicine, Haifa, Israel
Bossios A:: Dept of Respiratory Medicine and Allergy, Karolinska University Hospital and Dept of Medicine, Karolinska Institutet, Stockholm, Sweden
Dimakou K:: 5th Respiratory Department, "SOTIRIA" Hospital for Chest diseases, Athens, Greece
Jacob J:: Centre for Medical Image Computing, University College London, London, UK

UCL Respiratory, University College London, London, UK
Hurst JR:: UCL Respiratory, University College London, London, UK
Paggiaro PL:: Dept of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, Pisa, Italy
Ferri S:: Personalized Medicine, Asthma and Allergy, Humanitas Research Hospital IRCCS, Rozzano, Milan, Italy

Dept of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy
Hillas G:: 5th Respiratory Department, "SOTIRIA" Hospital for Chest diseases, Athens, Greece
Vogel-Claussen J:: Institute of Diagnostic and Interventional Radiology, German Center for Lung Research, Breath, Hannover Medical School, Hannover, Germany
Dettmer S:: Institute of Diagnostic and Interventional Radiology, German Center for Lung Research, Breath, Hannover Medical School, Hannover, Germany
Aliberti S:: Dept of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy

IRCCS Humanitas Research Hospital, Rozzano, Italy
Chalmers JD:: IRCCS Humanitas Research Hospital, Rozzano, Italy

School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
Polverino E:: Pneumology Dept, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona, Spain