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Health-related quality of life, social support, and caregiver burden between six and 120 months after heart transplantation: a Spanish multicenter cross-sectional study

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Delgado JF
  • González-Vilchez F
  • Arizón JM
  • Gómez M
  • Fuente L
  • Brossa V
  • Fernández J
  • Díaz B
  • Pascual D
  • Lage E
  • Sanz M
  • Manito N
  • Crespo-Leiro MG

Grupos

Abstract

A multicenter cross-sectional study was conducted to determine the current heart transplant (HTx) outcomes in Spain. Clinical and functional status, health-related quality of life (HRQoL), social support, and caregiver burden were analyzed in 303 adult transplant recipients (77.9% males) living with one functioning graft. Mean age at time of HTx (SD) was 56.4 (11.4) years, and the reason for transplantation in all patients was congestive heart failure. All patients had received a first heart transplant 6 (+/- 1), 12 (+/- 2), 36 (+/- 6), 60 (+/- 10), or 120 (+/- 20) months previously. Participants completed the Kansas City Cardiomyopathy Questionnaire (KCCQ), the EQ-5D, the Duke-UNC Functional Social Support Questionnaire, and the Zarit Caregiver Burden Scale. Reasonable HRQoL, social support, and caregiver burden levels were found at all time points, although a slight decrease in HRQoL was recorded at 120months (p0.033). Multivariate regression analyses showed that complications, comorbidities, and hospitalizations were associated with HRQoL (EQ-5D: 48.4% of explained variance, F-4,F-164=38.46, p<0.001; KCCQ overall summary score: 45.0%, F-3,F-198=54.073, p<0.001). Patient functional capabilities and complications affected caregiver burden (p<0.05). In conclusion, HTx patients reported reasonable levels of HRQoL with low caregiver burden. Clinical variables related to these outcomes included functional status, complications, and number of admissions.

Datos de la publicación

ISSN/ISSNe:
0902-0063, 1399-0012

CLINICAL TRANSPLANTATION  WILEY-BLACKWELL

Tipo:
Article
Páginas:
771-780
PubMed:
26074358
Factor de Impacto:
0,832 SCImago ℠
Cuartil:
Q2 SCImago ℠

Citas Recibidas en Web of Science: 24

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Keywords

  • caregiver; comorbidity; heart transplantation; outcome assessment; quality of life

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