Drugs in Focus: Octreotide Use in Children With Gastrointestinal Disorders.

Fecha de publicación: 09/09/2021 Fecha Ahead of Print: 09/09/2021

Autores de IIS La Fe

Carmen Ribes Koninckx

Autor

Participantes ajenos a IIS La Fe

Mas E
Borrelli O
Broekaert I
Martin de-Carpi, J
Dolinsek J
Miele E
Pienar C
Thomassen RA
Thomson M
Tzivinikos C
Benninga MA

Grupos

Enfermedad celíaca e Inmunopatología digestiva

Leader

Carmen Ribes Koninckx

Abstract

Octreotide, a somatostatin analogue, has been used for more than 20 years in children with gastrointestinal bleeding, chylothorax or chylous ascites, intestinal lymphangiectasia, pancreatitis, intestinal dysmotility, and severe diarrhoea; however, until now, there is a lack of randomised clinical trials evaluating the efficacy of this compound in childhood. Hence, we aimed to review the literature in order to determine the evidence of its use and safety in children, using PubMed from 2000 to 2021 with the search terms "octreotide" and "children" and "bleeding or chylous ascites or chylothorax or acute pancreatitis or lymphangiectasia or diarrhoea or intestinal dysmotility".

Datos de la publicación

ISSN/ISSNe:: 0277-2116, 1536-4801
Tipo:: Article
Páginas:: 1-6
DOI:: 10.1097/MPG.0000000000003294
Factor de Impacto:: 0,919 SCImago ℠
Cuartil:: Q1 SCImago ℠

Documentos

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Métricas

Filiaciones

Mas E:: 1Unité de Gastroentérologie, Hépatologie, Nutrition, Diabétologie et Maladies Héréditaires du Métabolisme, Hôpital des Enfants, CHU de Toulouse; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France.
Borrelli O:: 2Department of Paediatric Gastroenterology, Neurogastroenterology and Motility Unit, Great Ormond Street Hospital, London, UK.
Broekaert I:: 3Department of Paediatrics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Martin de-Carpi, J:: 4Department of Paediatric Gastroenterology, Hepatology and Nutrition, Hospital Sant Joan de Déu, Barcelona, Spain.
Dolinsek J:: 5Department of Paediatrics, University Medical Centre Maribor, Maribor, Slovenia.
Miele E:: 6Department of Translational Medical Science, Section of Paediatrics, University of Naples "Federico II", Naples Italy.
Pienar C:: 7Department of Paediatrics, 2 Paediatric Clinic, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Koninckx CR:: 8Paediatric Gastroenterology, La Fe University Hospital, Valencia, Spain.
Thomassen RA:: 9Department of Paediatric Medicine, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
Thomson M:: 10Centre for Paediatric Gastroenterology, Sheffield Children's Hospital NHS Foundation Trust, Sheffield, UK.
Tzivinikos C:: 11Department of Paediatric Gastroenterology, Al Jalila Children's Specialty Hospital, Dubai, UAE
Benninga MA:: 12Department of Paediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.