Circulating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage.

Autores de IIS La Fe

• Pedro Jose Morillas Blasco

  Autor

• Joan Manuel Quiles Izquierdo

  Autor

• Jose Manuel Maroñas Andrade

  Autor

• Estefanía Tarazón Melguizo

  Autor

• 

  Esther Roselló Lletí

  Autor

• Manuel Portoles Sanz

  Autor

• Jose Miguel Rivera Otero

  Autor

• Vicente Bertomeu Martinez

  Autor

Participantes ajenos a IIS La Fe

• Castillo J

Grupos

• Grupo de Investigación Clínica y Traslacional en Cardiología

  

  Investigador Principal

  Esther Roselló Lletí

Abstract

Increasing experimental evidence indicates that alterations in the extracellular matrix are implicated in hypertension and its chronic complications. Selected markers of extracellular matrix metabolism were investigated as potential biomarkers for hypertensive remodelling and correlated with the severity and extent of target organ damage (TOD) in patients with essential hypertension.