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  3. The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections.

The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections.

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Montaner S
  • Martin-Jaular L
  • Del Portillo HA
  • Bernal D

Grupos

Abstract

Parasites are the cause of major diseases affecting billions of people. As the inflictions caused by these parasites affect mainly developing countries, they are considered as neglected diseases. These parasitic infections are often chronic and lead to significant immunomodulation of the host immune response by the parasite, which could benefit both the parasite and the host and are the result of millions of years of co-evolution. The description of parasite extracellular vesicles (EVs) in protozoa and helminths suggests that they may play an important role in host-parasite communication. In this review, recent studies on parasitic (protozoa and helminths) EVs are presented and their potential use as novel therapeutical approaches is discussed.

Datos de la publicación

ISSN/ISSNe:
1664-3224, 1664-3224

Frontiers in immunology  FRONTIERS MEDIA SA

Tipo:
Article
Páginas:
433-433
PubMed:
25250031
Factor de Impacto:
2,389 SCImago ℠
Cuartil:
Q1 SCImago ℠

Citas Recibidas en Web of Science: 63

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Keywords

  • extracellular vesicles, helminth, immunomodulation, parasite, protozoa

Proyectos y Estudios Clínicos

ENSAYO MULTICENTRICO, ABIERTO, ALEATORIZADO, CONTROLADO, DE 24 MESES DE DURACION PARA EVALUAR LA EFICACIA, SEGURIDAD Y EVOLUCION DE LOS PARAMETROS CARDIOVASCULARES EN PACIENTES RECEPTORES DE UN TRANSPLANTE RENAL DE NOVO DESPUES DE LA CONVERSION TEMPRANA D E UN INHIBIDOR DE LA CALCINEURINA A EVEROLIMUS

Investigador Principal: DAVID RAMOS ESCORIHUELA

CRAD001A2429 . 2011

Cita

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