Impact of cardiovascular risk factors and inflammatory status on urinary 8-OHdG in essential hypertension.

Autores de IIS La Fe

• 

  Esther Roselló Lletí

  Autor

• Pedro Jose Morillas Blasco

  Autor

• Raquel Cortes Vergaz

  Autor

• 

  Luis Vicente Martínez Dolz

  Autor

• Luis Almenar Bonet

  Autor

• Placido Orosa Fernandez

  Autor

• Manuel Portoles Sanz

  Autor

• Vicente Bertomeu Martinez

  Autor

• Jose Miguel Rivera Otero

  Autor

Participantes ajenos a IIS La Fe

• de Burgos FG
• Grigorian L

Abstract

The urinary concentrations of 8-hydroxy-2'-deoxyguanosine (8-OHdG) reflect the oxidation status of hypertensive subjects and it can be used for monitoring oxidative stress changes. However, the influence of cardiovascular risk factors and inflammation on the urinary levels of this marker in hypertension (HT) has never evaluated. The purpose of this study was to analyze the impact of cardiovascular risk factors, and established inflammatory markers on 8-OHdG in essential HT.