Clinical evaluation of an evidence-based method based on food characteristics to adjust pancreatic enzyme supplements dose in cystic fibrosis.

Fecha de publicación: 02/12/2020 Fecha Ahead of Print: 02/12/2020

Autores de IIS La Fe

Joaquin Calvo Lerma

Autor
Carmen Ribes Koninckx

Autor

Participantes ajenos a IIS La Fe

Boon, Mieke
Colombo, Carla
de Koning, Barbara
Asseiceira, Ines
Garriga, Maria
Roca, Maria
Claes, Ine
Bulfamante, Anna
Walet, Sylvia
Pereira, Luisa
Ruperto, Mar
Masip, Etna
Asensio-Grau, Andrea
Giana, Arianna
Affourtit, Philine
Heredia, Ana
Vicente, Saioa
Andres, Ana
de Boeck, Kris
Hulst, Jessie

Grupos

Enfermedad celíaca e Inmunopatología digestiva

Leader

Carmen Ribes Koninckx

Abstract

Patients with cystic fibrosis (CF) and pancreatic insufficiency need pancreatic enzyme replacement therapy (PERT) for dietary lipids digestion. There is limited evidence for recommending the adequate PERT dose for every meal, and controlling steatorrhea remains a challenge. This study aimed to evaluate a new PERT dosing method supported by a self-management mobile-app.

Datos de la publicación

ISSN/ISSNe:: 1569-1993, 1873-5010
Tipo:: Article
Páginas:: 33-39
DOI:: 10.1016/j.jcf.2020.11.016
Factor de Impacto:: 2,049 SCImago ℠
Cuartil:: Q1 SCImago ℠

Documentos

No hay documentos

Métricas

Filiaciones

Calvo-Lerma, Joaquim:: Instituto de Investigación. 1Instituto de Investigación Sanitaria La Fe de Valencia. Cystic Fibrosis Unit. 46026 Valencia, Spain; Universitat Politècnica de València, Research Institute of Food Engineering for Development.
Boon, Mieke:: 2 Department of pediatrics, Center for Cystic Fibrosis, University Hospital Leuven. Leuven, Belgium.
Colombo, Carla:: 3 CF Center, Università degli Studi di Milano. Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico. 20122 Milan, Italy.
de Koning, Barbara:: 4 Department of Pediatrics, div of Gastro-Enterology and div of Respiratory Medicine and Allergology, Erasmus MC- Sophia Children's Hospital, University Hospital Rotterdam. Rotterdam, the Netherlands.
Asseiceira, Ines:: 5 Centro de Fibrose Quística, Hospital de Santa Maria, Lisboa. Lisbon, Portugal.
Garriga, Maria:: 6 Hospital Universitario Ramón y Cajal. Cystic Fibrosis Unit. 28034 Madrid, Spain.
Roca, Maria:: Instituto de Investigación. Instituto de Investigación Sanitaria La Fe de Valencia. Cystic Fibrosis Unit. 46026 Valencia, Spain.
Claes, Ine:: 2 Department of pediatrics, Center for Cystic Fibrosis, University Hospital Leuven. Leuven, Belgium.
Bulfamante, Anna:: 3 CF Center, Università degli Studi di Milano. Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico. 20122 Milan, Italy.
Walet, Sylvia:: 4 Department of Pediatrics, div of Gastro-Enterology and div of Respiratory Medicine and Allergology, Erasmus MC- Sophia Children's Hospital, University Hospital Rotterdam. Rotterdam, the Netherlands.
Pereira, Luisa:: 5 Centro de Fibrose Quística, Hospital de Santa Maria, Lisboa. Lisbon, Portugal.
Ruperto, Mar:: 6 Hospital Universitario Ramón y Cajal. Cystic Fibrosis Unit. 28034 Madrid, Spain.
Masip, Etna:: Instituto de Investigación. Instituto de Investigación Sanitaria La Fe de Valencia. Cystic Fibrosis Unit. 46026 Valencia, Spain.
Asensio-Grau, Andrea:: 8 Universitat Politècnica de València, Research Institute of Food Engineering for Development. 46022 Valencia, Spain.
Giana, Arianna:: 3 CF Center, Università degli Studi di Milano. Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico. 20122 Milan, Italy.
Affourtit, Philine:: 4 Department of Pediatrics, div of Gastro-Enterology and div of Respiratory Medicine and Allergology, Erasmus MC- Sophia Children's Hospital, University Hospital Rotterdam. Rotterdam, the Netherlands.
Heredia, Ana:: 8 Universitat Politècnica de València, Research Institute of Food Engineering for Development. 46022 Valencia, Spain.
Vicente, Saioa:: 6 Hospital Universitario Ramón y Cajal. Cystic Fibrosis Unit. 28034 Madrid, Spain.
Andres, Ana:: 8 Universitat Politècnica de València, Research Institute of Food Engineering for Development. 46022 Valencia, Spain.
de Boeck, Kris:: 2 Department of pediatrics, Center for Cystic Fibrosis, University Hospital Leuven. Leuven, Belgium.
Hulst, Jessie:: 9 Department of Pediatrics, div of Gastro-Enterology and div of Respiratory Medicine and Allergology, Erasmus MC- Sophia Children's Hospital, University Hospital Rotterdam. Rotterdam, the Netherlands; Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Canada.
Ribes-Koninckx, Carmen:: Instituto de Investigación. Instituto de Investigación Sanitaria La Fe de Valencia. Cystic Fibrosis Unit. 46026 Valencia, Spain.

Keywords

Coefficient of fat absorption, Cystic fibrosis, Digestion, In vitro digestion, Paediatrics, Pancreatic enzyme replacement therapy, Pancreatic insufficiency