Effects of Omalizumab Treatment in Patients With Recalcitrant Nasal Polyposis and Mild Asthma: A Multicenter Retrospective Study.

Fecha de publicación: 05/11/2020 Fecha Ahead of Print: 05/11/2020

Autores de IIS La Fe

Miguel Armengot Carceller

Autor
Mª Jose Gomez Gomez

Autor
Noelia Múñoz Fernández

Autor
Alfonso José García Piñero

Autor

Participantes ajenos a IIS La Fe

García-Navalón C
Doménech-Campos E
Miguel AG
Marco-Algarra J
Palop-Cervera M

Grupos

Biomedicina Molecular, Celular y Genómica

Leader

José María Millán Salvador

Abstract

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a clinical entity with specific features that impacts significantly on patient quality of life (QoL). CRSwNP is often associated with asthma and is difficult to control and manage despite pharmacological and/or surgical treatment. Omalizumab, a monoclonal anti-IgE antibody, has emerged as a putative therapeutic option.

Datos de la publicación

ISSN/ISSNe:: 1945-8924, 1945-8932
Tipo:: Article
Páginas:: 516-524
DOI:: 10.1177/1945892420972326
PubMed:: 33153272
Factor de Impacto:: 0,861 SCImago ℠
Cuartil:: Q1 SCImago ℠

Documentos

No hay documentos

Métricas

Filiaciones

Armengot-Carceller M:: Otolaryngology Department, University and Polytechnic La Fe Hospital, Valencia, Spain

Department of Surgery, Valencia University, Valencia, Spain

Instituto de Investigación. Grupo de Biomedicina Molecular, Celular y Genómica (BMCG), Health Research Institute La Fe, Valencia, Spain

CIBER of Respiratory Diseases, Instituto de Salut Carlos III, Ministerio de Ciencia e Innovación, Madrid, Spain
Gómez-Gómez MJ:: Otolaryngology Department, University and Polytechnic La Fe Hospital, Valencia, Spain
García-Navalón C:: Department of Surgery, Valencia University, Valencia, Spain

Otolaryngology Department, University General Hospital of Valencia, University of Valencia, Valencia, Spain
Doménech-Campos E:: Otolaryngology Department, Arnau de Vilanova Hospital, Valencia, Spain
Muñoz-Fernández N:: Otolaryngology Department, University and Polytechnic La Fe Hospital, Valencia, Spain
Miguel AG:: Otolaryngology Department, Manises Hospital, Valencia, Spain
Marco-Algarra J:: Department of Surgery, Valencia University, Valencia, Spain

Otolaryngology Department, University Clinic Hospital of Valencia, Valencia, Spain
Palop-Cervera M:: Pulmonology Department, Sagunto Hospital, Valencia, Spain
Piñero AG:: Otolaryngology Department, University and Polytechnic La Fe Hospital, Valencia, Spain

Keywords

IgE, SNOT-22, aspirin-exacerbated respiratory disease, chronic rhinosinusitis with nasal polyps, mild asthma, nasal polyps, omalizumab, quality of life, tissue eosinophilia, total nasal endoscopic polyp score