Analysis of the perfusion of the optic nerve using angio-OCT in glaucoma.

Autores de IIS La Fe

• Ana Hervás Ontiveros

  Autor

• Salvador García Delpech

  Autor

• Patricia Udaondo Mirete

  Autor

Grupos

• 

  Biomedicina Molecular, Celular y Genómica

Abstract

The introduction of optical coherence tomography angiography (OCT-A) has generated interest in evaluating vascular dysfunctions in the optic nerve head for the diagnosis and monitoring of glaucoma. The purpose of this study is to compare perfusion of the optic disc between normal subjects and subjects with glaucoma using OCT-A in order to detect changes in perfusion of the optic disc. Using the OCT-A AngioVue® system, an examination was performed on 40 eyes of 40 patients (20 with glaucoma and 20 healthy controls). Total radial peripapillary flow density (4.5×4.5mm) was measured at different levels of segmentation. The study demonstrated that the peripapillary vascular flow of OCT-A and exploration of the optic nerve head was better in the normal eyes compared to glaucoma patients. This review provides a comprehensive summary of the most important current and potential applications of OCT-A in glaucoma.

Keywords

• Angiografía por tomografía de coherencia óptica, Capa de fibra nerviosa retiniana peripapilar, Glaucoma, Macula, Mácula, Optical coherence tomography angiography, Perfusion, Perfusión, Peripapillary retinal nerve fibre layer