Gangliogliomas in the pediatric population.

Autores de IIS La Fe

• Tejada Arnold Rafeal Quiroz

  Autor

• Pablo Miranda Lloret

  Autor

• Margarita Mercedes Llavador Ros

  Autor

• Maria Estela Plaza Ramírez

  Autor

• Amparo Roca Barber

  Autor

• Juan Antonio Simal Julian

  Autor

• Carlos Botella Asuncion

  Autor

Participantes ajenos a IIS La Fe

• Pancucci G

Grupos

• Investigación Clínica y Traslacional en Cáncer

Abstract

Gangliogliomas are neoplastic lesions composed by a mixed population of neoplastic glial and dysplastic neural cells. They represent around 5% of all CNS tumors in the pediatric population. These usually are well-differentiated, slow-growing tumors, meaning that complete resection could cure most of these patients. Although most lesions remain stable over time after incomplete resection, some patients develop progression of the residual lesions: the optimal approach to treat these tumors is still to be defined.

Keywords

• BRAF V600E mutation, Child, Low-grade tumors